CenGEM | Publications

Recent Additions

NEW
Daykin, N., Mansfield, L., Payne, A. et al. (2016). What works for wellbeing in culture and sport? Report of a DELPHI process to support coproduction and establish principles and parameters of an evidence review. Perspectives in Public Health, (2016) doi: 10.1177/1757913916674038
NEW
Ghorbani, M., Payne, A. and Themis, M. (2016). Genome wide classification and characterisation of CpG sites in cancer and normal cells. Computers in Biology and Medicine, 68, pp. 57-66, (2016) doi: 10.1016/j.compbiomed.2015.09.023
NEW
Surendran, P., Drenos, F., Young, R. et al. (2016). Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Surendran, P., Drenos, F., Young, R. et al. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet 48, 1151–1161 (2016). doi: 10.1038/ng.3654
NEW
Morris, R., Cooper, J., Shah, T., ..., Drenos, F. et al. (2016). Marginal role for 53 common genetic variants in cardiovascular disease prediction. Heart, 2016, 102 (20), pp. 1640 - 1647 doi: 10.1136/heartjnl-2016-309298
NEW
Beaney, K., Cooper, J., Drenos, F. and Humphries, S. (2016). Assessment of the clinical utility of adding common single nucleotide polymorphism genetic scores to classical risk factor algorithms in coronary heart disease risk prediction in UK men. Clinical Chemistry and Laboratory Medicine, 2017, 55 (10), pp. 1605 - 1613 doi: 10.1515/cclm-2016-0984
NEW
De, R., Verma, S., Holzinger, E., ..., Drenos, F. et al. (2016). Identifying gene–gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts. Human Genetics, 2017, 136 (2), pp. 165 - 178 doi: 10.1007/s00439-016-1738-7
NEW
Dong, W., Yang, D., Zhou, X., Kastiukas, G. and Zhang, B. (2016). Experimental and numerical investigations on fracture process zone of rock-concrete interface. Dong, W. et al. (2017) 'Experimental and numerical investigations on fracture process zone of rock-concrete interface', Fatigue and Fracture of Engineering Materials and Structures, 40 (5), pp 820 - 835. doi: 10.1111/ffe.12558.
NEW
Ganesan, K., Gokhan, E., De Munter, S., Bollen, M., Vagnarelli, P., Peti, W. and Page, R. (2016). The Ki-67 and Repoman mitotic phosphatases assemble via an identical, yet novel mechanism. Kumar GS, Gokhan E, De Munter S, Bollen M, Vagnarelli P, Peti W, Page R. The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism. Elife. 2016 Aug 30;5:e16539. doi: 10.7554/eLife.16539.001
NEW
Khachatryan, V., Sirunyan, A., Tumasyan, A., ..., Tosi, S. et al. (2016). Search for Narrow Resonances in Dijet Final States at root s=8 TeV with the Novel CMS Technique of Data Scouting.
NEW
Kargaran, P., Yasaei, H., Anjomani-Virmouni, S., Mangiapane, G. and Slijepcevic, P. (2016). Analysis of alternative lengthening of telomere markers in BRCA1 defective cells. Genes Chromosomes and Cancer, 55 (11): pp. 864 - 876, (2016) doi: 10.1002/gcc.22386
NEW
Ehret, G., Ferreira, T., Chasman, D., ..., Drenos, F. et al. (2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Ehret, G., Ferreira, T., Chasman, D. et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet 48, 1171–1184 (2016). doi: 10.1038/ng.3667
NEW
Liu, C., Kraja, A., Smith, J., ..., Drenos, F. et al. (2016). Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nature Genetics, 2016, 48 (10), pp. 1162 - 1170 doi: 10.1038/ng.3660
NEW
Beaney, K., Cooper, J., McLachlan, S., ..., Drenos, F. et al. (2016). Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids. Cardiovascular diabetology, 2016, 15 (1), pp. 115 - 115 doi: 10.1186/s12933-016-0435-0
NEW
Hoefken, T., Kennedy, H., Haack, T., ..., Mackay, R. et al. (2016). Sudden cardiac death due to deficiency of the mitochondrial inorganic pyrophosphatase PPA2. Kennedy H, Haack TB, Hartill V, Mataković L, Baumgartner ER, Potter H, Mackay R, Alston CL, O’Sullivan S, McFarland R, Connolly G. Sudden cardiac death due to deficiency of the mitochondrial inorganic pyrophosphatase PPA2. The American Journal of Human Genetics. 2016 Sep 1;99(3):674-82. doi: 10.1016/j.ajhg.2016.06.027
NEW
Papa, S. and Bubici, C. (2016). Linking apoptosis to cancer metabolism: Another missing piece of JuNK. Salvatore Papa & Concetta Bubici (2016) Linking apoptosis to cancer metabolism: Another missing piece of JuNK, Molecular & Cellular Oncology, 3:2, doi: 10.1080/23723556.2015.1103398
NEW
Tzelepis, K., Koike-Yusa, H., De Braekeleer, E., ..., Pina, C. et al. (2016). A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia. Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M. A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia. Cell reports. 2016 Oct 18;17(4):1193-205. doi: 10.1016/j.celrep.2016.09.079
NEW
Chudasama, D., Freydina, M., Freidin, M., Leung, M., Fernandez, A., Rice, A., Nicholson, A., Karteris, E., Anikin, V. and Lim, E. (2016). Inertia based microfluidic capture and characterisation of circulating tumour cells for the diagnosis of lung cancer. Annals of Translational Medicine, 4 (24), 2016 doi: 10.21037/atm.2016.12.28
NEW
Martin, C., Murray, J., Carroll, P., ..., Vagnarelli, P. et al. (2016). Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis. Genes & Development, 30(19), pp. 2158-72. doi: 10.1101/gad.286351.116.
NEW
Kaur, A., Sultan, S., Murugaiah, V., Pathan, A., Alhamlan, F., Karteris, E. and Kishore, U. (2016). Human C1q Induces Apoptosis in an Ovarian Cancer Cell Line via Tumor Necrosis Factor. Frontiers in Immunology, 7, 599, pp. 1- 13. doi: 10.3389/fimmu.2016.00599.
NEW
Khonsari, H., Schneider, M., Al-Mahdawi, S., Chianea, Y., Themis, M., Parris, C., Pook, M. and Themis, M. (2016). Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblasts. Khonsari, H., Schneider, M., Al-Mahdawi, S. et al. Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblasts. Gene Ther 23, 846–856 (2016). doi: 10.1038/gt.2016.61
NEW
Tulasidas, S., Mackay, R., Hudson, C. and Balachandran, W. (2016). Security Framework for Managing Data Security within Point of Care Tests. Journal of Software Engineering and Applications
NEW
Corda, G., Sala, G., Lattanzio, R., ..., Ermler, S., Silva, E., Vagnarelli, P. et al. (2016). Functional and prognostic significance of the genomic amplification of frizzled receptor 6 ( FZD6 ) in breast cancer. Corda G, Sala G, Lattanzio R, Iezzi M, Sallese M, Fragassi G, Lamolinara A, Mirza H, Barcaroli D, Ermler S, Silva E. Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer. The Journal of pathology. 2017 Feb;241(3):350-61. doi: 10.1002/path.4841
NEW
McLachlan, S., Giambartolomei, C., White, J., ..., Drenos, F. et al. (2016). Replication and characterization of association between ABO SNPs and red blood cell traits by meta-analysis in Europeans. PLoS ONE, 2016, 11 (6), pp. 1 - 18 doi: 10.1371/journal.pone.0156914
NEW
Pondman, K., Paudyal, B., Sim, R., ..., Stenbeck, G. et al. (2016). Pulmonary surfactant protein SP-D opsonises carbon nanotubes and augments their phagocytosis and subsequent pro-inflammatory immune response. Pondman KM, Paudyal B, Sim RB, Kaur A, Kouser L, Tsolaki AG, Jones LA, Salvador-Morales C, Khan HA, ten Haken B, Stenbeck G. Pulmonary surfactant protein SP-D opsonises carbon nanotubes and augments their phagocytosis and subsequent pro-inflammatory immune response. Nanoscale. 2017;9(3):1097-109. doi: 10.1039/C6NR08807D
NEW
Altshuler, D., Durbin, R., Abecasis, G., ..., Sisu, C. et al. (2016). A global reference for human genetic variation. NATURE, 2015, 526 (7571), pp. 68 - + (20) doi: 10.1038/nature15393
NEW
Mankarious, A., Dave, F., Pados, G., Tsolakidis, D., Gidron, Y., Pang, Y., Thomas, P., Hall, M. and Karteris, E. (2016). The pro-social neurohormone oxytocin reverses the actions of the stress hormone cortisol in human ovarian carcinoma cells in vitro. International Journal of Oncology, 48: pp.1805-1814. doi: 10.3892/ijo.2016.3410.
NEW
Rogers-Broadway, K., Chudasama, D., Pados, G., Tsolakidis, D., Goumenou, A., Hall, M. and Karteris, E. (2016). Differential effects of rapalogues, dual kinase inhibitors on human ovarian carcinoma cells in vitro. International Journal of Oncology, 49(1): pp. 133 - 143, (2016) doi: 10.3892/ijo.2016.3531
NEW
Bourton, E. (2016). EP-2069: CDC73 deficiency: a syndrome with multiple tumours is predicted to show excessive radiosensitivity. ESTRO 35, (2016)
NEW
Dimude, J., Midgley-Smith, S., Stein, M. and Rudolph, C. (2016). Replication termination: Containing fork fusion-mediated pathologies in escherichia coli. Genes, 7(8):40, pp. 1-22, (2016) doi: 10.3390/genes7080040
NEW
Cheng, T., Thompson, D., O'Mara, T., ..., Lewis, A. et al. (2016). Five endometrial cancer risk loci identified through genome-wide association analysis. Cheng, T., Thompson, D., O'Mara, T. et al. Five endometrial cancer risk loci identified through genome-wide association analysis. Nat Genet 48, 667–674 (2016). doi: 10.1038/ng.3562
NEW
Lewis, A., Cave, P., Stern, M. et al. (2016). Singing for Lung Health—a systematic review of the literature and consensus statement. Lewis, A., Cave, P., Stern, M. et al. Singing for Lung Health—a systematic review of the literature and consensus statement. npj Prim Care Resp Med 26, 16080 (2016). doi: 10.1038/npjpcrm.2016.80
NEW
Wijesuriya, S., Burugapalli, K., Mackay, R., Ajaezi, G. and Balachandran, W. (2016). Chemically roughened solid silver: A simple, robust and broadband SERS substrate. Sensors, 16(10): 1742, (2016) doi: 10.3390/s16101742
NEW
Silva, E., Ermler, S., Widschwendter, M. and Maund, P. (2016). Abstract P6-05-03: Investigating the effects of low-dose mixtures of environmental contaminants on breast cancer initiation. Poster Session Abstracts, 2017 doi: 10.1158/1538-7445.sabcs16-p6-05-03
NEW
Warren, H., Evangelou, E., Cabrera, C., ..., Drenos, F. et al. (2016). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature Genetics, 2017, 49 (3), pp. 403 - 415 doi: 10.1038/ng.3768
NEW
Seifert, W., Posor, Y., Schu, P., Stenbeck, G., Mundlos, S., Klaassen, S., Nürnberg, P., Haucke, V., Kornak, U. and Kühnisch, J. (2016). The progressive ankyloses protein ANK facilitates clathrin- and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface. Seifert W, Posor Y, Schu P, Stenbeck G, Mundlos S, Klaassen S, Nürnberg P, Haucke V, Kornak U, Kühnisch J. The progressive ankylosis protein ANK facilitates clathrin-and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface. Human molecular genetics. 2016 Sep 1;25(17):3836-48. doi: 10.1093/hmg/ddw230
NEW
Drenos, F., Smith, G., Ala-Korpela, M. et al. (2016). Metabolic characterization of a rare genetic variation within APOC3 and its lipoprotein lipase-independent effects. Drenos F, Davey Smith G, Ala-Korpela M, Kettunen J, Würtz P, Soininen P, Kangas AJ, Dale C, Lawlor DA, Gaunt TR, Casas JP. Metabolic characterization of a rare genetic variation within APOC3 and its lipoprotein lipase–independent effects. Circulation: Cardiovascular Genetics. 2016 Jun;9(3):231-9. doi: 10.1161/CIRCGENETICS.115.001302
NEW
Pednekar, L., Pathan, A., Paudyal, B., ..., Stenbeck, G. et al. (2016). Analysis of the interaction between globular head modules of candidate receptor gC1qR. Pednekar, L., Pathan, A.A., Paudyal, B., Tsolaki, A.G., Kaur, A., Abozaid, S.M., Kouser, L., Khan, H,A., Peerschke, E.I., Shamji, M.H., Stenbeck, G., Ghebrehiwet, B. and Kishore, U. (2016) 'Analysis of the Interaction between Globular Head Modules of Human C1q and Its Candidate Receptor gC1qR', Frontiers in Immunology, 7, 567, pp. 1-12. doi: 10.3389/fimmu.2016.00567.
NEW
de Castro, I., Gokhan, E. and Vagnarelli, P. (2016). Resetting a functional G1 nucleus after mitosis. Chromosoma 125, pp. 607 - 619. doi: 10.1007/s00412-015-0561-6.
NEW
Wang, Q., Niironen, M., Tynkkynen, T., ..., Drenos, F. et al. (2016). Metabolic signatures of birthweight in 18 288 adolescents and adults. International Journal of Epidemiology, 45 (5), pp. 1539 - 1550, doi: 10.1093/ije/dyw255.
NEW
Slijepcevic, P. (2016). Evolutionary Epistemology: Reviewing and Reviving with New Data the Research Programme for Distributed Biological Intelligence. BioSystems
NEW
Motevalli, A., Yasaei, H., Virmouni, S., Mirabdulhagh, M., Slijepcevic, P. and Roberts, T. (2016). Telomere elongation in the breast cancer cell line 21NT after treatment with an epigenetic modifying drug. Journal of Cancer Therapy, 07 (10): pp. 700 - 711,(2016) doi: 10.4236/jct.2016.710072
NEW
Slijepcevic, P. (2016). Mechanisms of the evolutionary chromosome plasticity: Integrating the ‘Centromere-from-Telomere' hypothesis with telomere length regulation. Cytogenetic and Genome Research, 148(4): pp. 268-278, (2016) doi: 10.1159/000447415
NEW
Hill, A., Sullivan, A., Chalmers, J., ..., Harvey, A. et al. (2018). British Thoracic Society guideline for bronchiectasis in adults (BMJ Open). Hill AT, Sullivan AL, Chalmers JD, et al. (2018) 'British Thoracic Society guideline for bronchiectasis in adults', BMJ Open Respiratory Research 5:e000348, pp. 1-16. doi:10.1136/bmjresp-2018-000348
NEW
Hill, A., Sullivan, A., Chalmers, J., ..., Harvey, A. et al. (2018). British Thoracic Society Guideline for bronchiectasis in adults. Hill, A.T., Sullivan, A.L., Chalmers, J.D., De Soyza, A., Elborn, J.S., Floto, R.A., Grillo, L., Gruffydd-Jones, K., Harvey, A., S Haworth, C., Hiscocks, E., R Hurst, J., Johnson, C., Kelleher, W.P., Bedi, P., Payne, K., Saleh, H., Screaton, N.J., Smith, M., Tunney, M., Whitters, D., Wilson, R. and Loebinger, M.R. (2019) 'British Thoracic Society Guideline for bronchiectasis in adults', Thorax, 74 (Suppl 1), pp. 1-69. doi: 10.1136/thoraxjnl-2018-212463.
NEW
Yue, W., Wang, Z., Chen, H., Payne, A. and Liu, X. (2018). Machine Learning with Applications in Breast Cancer Diagnosis and Prognosis. Designs, 2018, 2 (2), pp. 13 - 13 doi: 10.3390/designs2020013
NEW
Mansfield, L., Kay, T., Meads, C., ..., Payne, A. et al. (2018). Sport and dance interventions for healthy young people (15-24 years) to promote subjective wellbeing: A systematic review. Mansfield, L., Kay, T., Meads, C., Grigsby Duffy, L., Lane, J., John, A., Daykin, N., Dolan, P., Testoni, S., Julier, G., Payne, A., Tomlinson, A. and Victor, C. (2018) Sport and dance interventions for healthy young people (15–24 years) to promote subjective well-being: a systematic review BMJ Open 8, e020959, pp. 1-6. doi: 10.1136/bmjopen-2017-020959.
NEW
Vidotto, L., Bigliassi, M., Jones, M., Harvey, A. and Carvalho, C. (2018). Stop Thinking! I Can't! Do Attentional Mechanisms Underlie Primary Dysfunctional Breathing?. Frontiers in Physiology. 9, 782, pp. 1-4. doi: 10.3389/fphys.2018.00782.
NEW
Harvey, A., Domislic, B. and Shannon, H. (2018). Developmental outcome measures in neonatal physiotherapy services of the United Kingdom: a survey of current use, and facilitators and barriers to their implementation. Association of Paediatric Chartered Physiotherapists Journal, 9 (1)
NEW
Aveyard, P., Lindson, N., Tearne, S., ..., Anderson, R. et al. (2018). Nicotine preloading for smoking cessation: the Preloading RCT. Health Technology Assessment, 22(41). doi: 10.3310/hta22410.
NEW
Yang, T., Chong, W., Wang, W., ..., Tanos, B. et al. (2018). Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components. Yang, T.T., Chong, W., Wang, W.-J. Mazo, G., Tanos, B., Chen, Y.D., Weng, R.R., Huang, C.-E., ,Jane, W.N., Tsou, M-F.B. and Liao, J.-C. (2018) 'Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components. Nature Communications, 9 (1), 2023, pp. 1-11.. doi: 10.1038/s41467-018-04469-1.
NEW
Yao, H., Zhang, B., Zhang, P. and Li, M. (2018). A novel kernel for text classification based on semantic and statistical information. Computing and Informatics, 37 (4), pp. 992 - 1010. doi: 10.4149/cai_2018_4_992.
NEW
Dalke, C., Neff, F., Bains, S., ..., Slijepcevic, P. et al. (2018). Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk. Dalke, C., Neff, F., Bains, S.K. et al. Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk. Radiat Environ Biophys doi: 10.1007/s00411-017-0728-z
NEW
Chudasama, D., Aladag, Z., Felicien, M., Hall, M., Beeson, J., Asadi, N., Gidron, Y., Karteris, E. and Anikin, V. (2018). Prognostic value of the DNA integrity index in patients with malignant lung tumors. Oncotarget, 2018, 9 (30), pp. 21281 - 21288 doi: 10.18632/oncotarget.25086
NEW
Lilue, J., Doran, A., Fiddes, I., ..., Sisu, C. et al. (2018). Sixteen diverse laboratory mouse reference genomes define strain specific haplotypes and novel functional loci. Nature Genetics, 2018 doi: 10.1038/s41588-018-0223-8
NEW
Hemani, G., Zheng, J., Elsworth, B., ..., Haberland, V. et al. (2018). The MR-base platform supports systematic causal inference across the human phenome. eLife, 7, e34408, pp. 1 - 29. doi: 10.7554/eLife.34408.
NEW
Karteris, E. (2018). Prognostic value of the DNA Integrity Index in patients with malignant lung tumours.
NEW
Hernandez, V. and Seda, M. (2018). An FDA-Approved Drug Screen for Compounds Influencing Craniofacial Skeletal Development and Craniosynostosis. Seda M, Geerlings M, Lim P, Jeyabalan-Srikaran J, Cichon AC, Scambler PJ, Beales PL, Hernandez-Hernandez V, Stoker AW, Jenkins D. An FDA-Approved Drug Screen for Compounds Influencing Craniofacial Skeletal Development and Craniosynostosis. Molecular syndromology. 2019;10(1-2):98-114.
NEW
Papa, S. and Bubici, C. (2018). Feeding the Hedgehog: A new meaning for JNK signalling in liver regeneration. Journal of Hepatology, 2018 doi: 10.1016/j.jhep.2018.05.026
NEW
Lee, N., Carella, M., Papa, S. and Bubici, C. (2018). High expression of glycolytic genes in Cirrhosis correlates with the risk of developing liver cancer. Frontiers in Cell and Developmental Biology, 2018, 6 (OCT) doi: 10.3389/fcell.2018.00138
NEW
Papa, S., Choy, P. and Bubici, C. (2018). The ERK and JNK pathways in the regulation of metabolic reprogramming. Oncogene doi: 10.1038/s41388-018-0582-8
NEW
Moris, N., Edri, S., Seyres, D., Kulkarni, R., Domingues, A., Balayo, T., Frontini, M. and Pina, C. (2018). Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity. Stem Cells, 36 (12), pp. 1828 - 1838. doi: 10.1002/stem.2919.
NEW
Domingues, A., Kulkarni, R., Giotopoulos, G., ..., Pina, C. et al. (2018). Loss of Kat2A Enhances Transcriptional Noise and Depletes Acute Myeloid Leukemia Stem-Like Cells. bioRxiv, 2018 446096 doi: 10.1101/446096
NEW
Tzelepis, K., De Braekeleer, E., Aspris, D., ..., Pina, C. et al. (2018). SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Tzelepis, K., De Braekeleer, E., Aspris, D. et al. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nat Commun 9, 5378 (2018). doi: 10.1038/s41467-018-07620-0
NEW
Zhang, B., Li, S., Huang, Z., Rahi, B., Wang, Q. and Li, M. (2018). Transfer learning-based online multiperson tracking with Gaussian process regression. Concurrency Computation, 2018, 30 (23):e4917 (11) doi: 10.1002/cpe.4917
NEW
Frankish, A., Diekhans, M., Ferreira, A., ..., Sisu, C. et al. (2018). GENCODE reference annotation for the human and mouse genomes. Nucleic Acids Research, 2018 doi: 10.1093/nar/gky955
NEW
Sirunyan, A., Tumasyan, A., Adam, W., ..., Tosi, S. et al. (2018). Precision measurement of the structure of the CMS inner tracking system using nuclear interactions.
NEW
Roller, M., Navarro, F., Fiddes, I., ..., Sisu, C. et al. (2018). Repeat associated mechanisms of genome evolution and function revealed by theMus caroliandMus paharigenomes. Genome Res, 2018 doi: 10.1101/gr.234096.117
NEW
Bikkul, M., Faragher, R., Worthington, G., ..., Slijepcevic, P., Makarov, E. et al. (2018). Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform. Bikkul, M.U., Faragher, R.G.A., Worthington, G., Meinke, P., Kerr, A.R.W., Sammy, A., Riyahi, K., Horton, D., Schirmer, E.C., Hubank, M., Kill, I.R., Anderson, R.M., Slijepcevic, P., Makarov, E. and Bridger, J.M. (2019) 'Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform', Genes, Chromosomes and Cancer, 58(6), pp. 341-356. doi: 10.1002/gcc.22711.
NEW
Karteris, E., Patel, V., Chen, J. et al. (2018). Functional Cardiac Orexin Receptors: Role of Orexin-B/Orexin 2 Receptor in Myocardial Protection. Clinical Science doi: 10.1042/CS20180150.
NEW
Vagnarelli, P. and Sales Gil, R. (2018). Protein Phosphatases in chromatin structure and function. BBA Molecular Cell Research, 2019, 1866(1): 90 - 101 doi: 10.1016/j.bbamcr.2018.07.016
NEW
Rogers‑Broadway, K., Kumar, J., Sisu, C., ..., Karteris, E. et al. (2018). Differential expression of mTOR components in endometriosis and ovarian cancer: Effects of rapalogues and dual kinase inhibitors on mTORC1 and mTORC2 stoichiometry. International Journal of Molecular Medicine, 2019, 43, pp. 47-56
NEW
Kouser, L., Paudyal, B., Kaur, A., Stenbeck, G., Jones, L., Abozaid, S., Stover, C., Flauhat, E., Sim, R. and Kishore, U. (2018). Human Properdin Opsonizes Nanoparticles and Triggers a Potent Pro-inflammatory Response by Macrophages without Involving Complement Activation. Kouser L, Paudyal B, Kaur A, Stenbeck G, Jones LA, Abozaid SM, Stover CM, Flahaut E, Sim RB and Kishore U (2018) Human Properdin Opsonizes Nanoparticles and Triggers a Potent Pro-inflammatory Response by Macrophages without Involving Complement Activation. Front. Immunol. 9:131. doi: 10.3389/fimmu.2018.00131
NEW
Karteris, E., Kawan, M., Kyrou, I., Ramanjaneya, M., Williams, K., Jeyaneethi, J. and Randeva, H. (2018). Involvement of the glutamine RF-amide peptide (QRFP) and its cognate receptor GPR103 in prostate cancer. Journal of Oncology doi: 10.3892/or.2018.6893
NEW
Dimude, J., Stein, M., Andrzejewska, E., Khalifa, M., Gajdosova, A., Retkute, R., Skovgaard, O. and Rudolph, C. (2018). Origins Left, Right, and Centre: Increasing the Number of Initiation Sites in the Escherichia coli Chromosome. Dimude, J., Stein, M., Andrzejewska, E., Khalifa, M., Gajdosova, A., Retkute, R., Skovgaard, O. and Rudolph, C. (2018) ‘Origins Left, Right, and Centre: Increasing the Number of Initiation Sites in the Escherichia coli Chromosome’, Genes, 9 (8), 376, pp. 1-21. doi: 10.3390/genes9080376.
NEW
Midgley-Smith, S., Dimude, J. and Rudolph, C. (2018). A role for 3’ exonucleases at the final stages of chromosome duplication in Escherichia coli. Nucleic Acids Research
NEW
Quint, J., Moore, E., Lewis, A. et al. (2018). Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research. npj Primary Care Respiratory Medicine, 2018, 28 (1): 21 doi: 10.1038/s41533-018-0089-3
NEW
Lewis, A., Cave, P. and Hopkinson, N. (2018). Singing for Lung Health: service evaluation of the British Lung Foundation programme. Perspectives in Public Health, 2018, 138 (4), pp. 215 - 222 doi: 10.1177/1757913918774079
NEW
Lewis, A., Platt, J., Gent, P., Cave, P. and Young, R. (2018). The Lung Cycle – a day of creative investigation into singing for breathing. [rb&hArts newspaper], 2018, pp. 1 - 8
NEW
Lewis, A. and Thomas, J. (2018). COPD and Singing for Lung Health: A Patient and Clinician Perspective. Pulmonary Therapy, 2018, 4 (2), pp. 121 - 124 doi: 10.1007/s41030-018-0063-9
NEW
Sirunyan, A., Tumasyan, A., Adam, W., ..., Tosi, S. et al. (2018). Observation of the chi(b1)(3P) and chi(b2)(3P) and Measurement of their Masses. PHYSICAL REVIEW LETTERS, 2018, 121 (9), pp. ? - ? (17) doi: 10.1103/PhysRevLett.121.092002
NEW
Themis, M. (2018). Three-dimensional cell culture: From evolution to revolution. Philos Trans R Soc Lond B Biol Sci, 2018, 373 pp. 1750 - 1750 doi: 10.1098/rstb.2017.0216
NEW
Al-Allaf, F., Abduljaleel, Z., Athar, M., ..., Themis, M. et al. (2018). Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia. Non-coding RNA Research, 2018, 4 (1), pp. 1 - 14 doi: 10.1016/j.ncrna.2018.11.005
NEW
Tijani, M., Munis, A., Perry, C., ..., Themis, M. et al. (2018). Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes. Molecular Therapy - Methods and Clinical Development, 2018, 10 pp. 303 - 312 doi: 10.1016/j.omtm.2018.07.013
NEW
Vagnarelli, P. and Alessi, D. (2018). PP1 Phosphatase Complexes: Undruggable No Longer. Cell, 2018, 174 pp. 1049 - 1051 doi: 10.1016/j.cell.2018.08.007
NEW
Vagnarelli, P. and Sales Gil, R. (2018). Ki-67: More Hidden behind a ‘Classic Proliferation Marker. Trends in Biochemical Sciences, 2018, 43(10): 747 - 748 doi: 10.1016/j.tibs.2018.08.004
NEW
Tummala, H., Collopy, L., Walne, A., ..., Tomita, K. et al. (2018). Homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita–like phenotypes. Hemanth Tummala, Laura C. Collopy, Amanda J. Walne, Alicia Ellison, Shirleny Cardoso, Tekin Aksu, Nese Yarali, Deniz Aslan, Rüştü Fikret Akata, Juliana Teo, Zhou Songyang, Nikolas Pontikos, Jude Fitzgibbon, Kazunori Tomita, Tom Vulliamy, Inderjeet Dokal; Homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita–like phenotypes. Blood 2018; 132 (12): 1349–1353. doi: 10.1182/blood-2018-03-837799
NEW
Slijepcevic, P. (2018). Genome dynamics over evolutionary time: “C-value enigma” in light of chromosome structure. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2018 doi: 10.1016/j.mrgentox.2018.05.005
NEW
Suleman, S., Payne, A., Bowden, J., ..., Themis, M. et al. (2021). Lentivirus tethering to the genome is associated with transcription factor binding sites that favour virus survival. Human Gene Therapy, 32 (19-20), pp. A138 - A139. doi: 10.1089/hum.2021.29180.abstracts.
NEW
Hutt, S., Mihaies, D., Karteris, E., Michael, A., Payne, A. and Chatterjee, J. (2021). Statistical Meta-Analysis of Risk Factors for Endometrial Cancer and Development of a Risk Prediction Model Using an Artificial Neural Network Algorithm. Cancers, 13 (15), 3689, pp. 1 - 22. doi: 10.3390/cancers13153689.
NEW
Zhang, B., Nguyen, A., Narayan, R. and Huang, J. (2021). Direct ink writing of vancomycin-loaded polycaprolactone/ polyethylene oxide/ hydroxyapatite 3D scaffolds. Journal of the American Ceramic Society, 105 (3), pp. 1821 - 1840. doi: 10.1111/jace.18048.
NEW
Kerslake, R., Hall, M., Vagnarelli, P., Jeyaneethi, J., Randeva, H., Pados, G., Kyrou, I. and Karteris, E. (2021). A pancancer overview of FBN1, asprosin and its cognate receptor OR4M1 with detailed expression profiling in ovarian cancer. Kerslake, R., Hall, M., Vagnarelli, P., Jeyaneethi, J., Randeva, H.S., Pados, G. ... Karteris, E. (2021). A pancancer overview of FBN1, asprosin and its cognate receptor OR4M1 with detailed expression profiling in ovarian cancer. Oncology Letters, 22, 650. doi: 10.3892/ol.2021.12911
NEW
Tsakaneli, A., Carregari, V., Morini, M., ..., Makarov, E. et al. (2021). MYC regulates metabolism through vesicular transfer of glycolytic kinases. Open Biology, 11(12), 210276, pp. 1-15. doi: 10.1098/rsob.210276.
NEW
Esposito, A. (2021). Cooperation of partially transformed clones: An invisible force behind the early stages of carcinogenesis. Royal Society Open Science, 8 (2), 201532, pp. 1 - 12. doi: 10.1098/rsos.201532.
NEW
Amin, H., Cordell, H., Martin-Ruiz, C., Robinson, L., Kirkwood, T., Blakemore, A. and Drenos, F. (2021). No Evidence That Genetic Variation at the Klotho Locus Is Associated With Longevity in Caucasians from the Newcastle 85+ Study and the UK Biobank. Amin, H.A. et al. (2022) 'No Evidence That Genetic Variation at the Klotho Locus Is Associated With Longevity in Caucasians from the Newcastle 85+ Study and the UK Biobank', The Journals of Gerontology: Series A, 77 (3), pp. 457 - 461. doi: 10.1093/gerona/glab361.
NEW
Slijepcevic, P. (2021). Serial Endosymbiosis Theory: From biology to astronomy and back to the origin of life. BioSystems, 202, 104353, pp. 1 - 9. doi: 10.1016/j.biosystems.2021.104353.
NEW
Beymer, D., Rajan, D., Coy, A., ..., Karteris, E. et al. (2021). Erratum: On the role of artificial intelligence in medical imaging of COVID-19 (Patterns (2021) 2(6), (S2666389921000957), (10.1016/j.patter.2021.100269)). Patterns, 2021, 2 (8), 100330, pp. 1 - 1. doi: 10.1016/j.patter.2021.100330.
NEW
Themis, M., Al-Haque, S., Wang, W. et al. (2021). Application of InGetox to assess the genotoxicity of LV and AAV vectors. Human Gene Therapy, 32 (19-20), pp. A136 - A136. doi: 10.1089/hum.2021.29180.abstracts.
NEW
Yin, S., Liu, Y., Dai, S., Zhang, B., Qu, Y., Zhang, Y., Choe, W. and Bi, J. (2021). Mechanism Study of Thermally Induced Anti-Tumor Drug Loading to Engineered Human Heavy-Chain Ferritin Nanocages Aided by Computational Analysis. Yin, S. et al. (2021) ‘Mechanism Study of Thermally Induced Anti-Tumor Drug Loading to Engineered Human Heavy-Chain Ferritin Nanocages Aided by Computational Analysis’, Biosensors, 11 (11), 444, pp. 1 - 17. doi: 10.3390/bios11110444.
NEW
Katopodis, P., Anikin, V., Kishore, U., Carter, T., Hall, M., Asadi, N., Polychronis, A. and Karteris, E. (2021). Circulating tumour cells and circulating cell-free DNA in lung cancer patients: A comparison between Thoracotomy and Video-Assisted Thoracoscopic Surgery. BMJ Open Respiratory Research 8, e000917, pp. 1 - 10. doi: 10.1136/bmjresp-2021-000917.
NEW
Haas, K., Fries, M., Venkitaraman, A. and Esposito, A. (2021). Single-Cell Biochemical Multiplexing by Multidimensional Phasor Demixing and Spectral Fluorescence Lifetime Imaging Microscopy. Frontiers in Physics, 9, 637123, pp. 1 - 14. doi: 10.3389/fphy.2021.637123.
NEW
Yin, S., Wang, Y., Zhang, B., Qu, Y., Liu, Y., Dai, S., Zhang, Y., Wang, Y. and Bi, J. (2021). Engineered human heavy-chain ferritin with half-life extension and tumor targeting by PAS and RGDK peptide functionalization. Yin, S. et al. (2021) ‘Engineered Human Heavy-Chain Ferritin with Half-Life Extension and Tumor Targeting by PAS and RGDK Peptide Functionalization’, Pharmaceutics, 13 (4), 521, pp. 1 - 16. doi: 10.3390/pharmaceutics13040521.
NEW
Philip, K., Lewis, A., Buttery, S., McCabe, C., Manivannan, B., Fancourt, D., Orton, C., Polkey, M. and Hopkinson, N. (2021). Physiological demands of singing for lung health compared with treadmill walking. BMJ Open Respiratory Research, 8 (1), e000959, pp. 1-7. doi: 10.1136/bmjresp-2021-000959.
NEW
Houlden, A. and Mackay, R. (2021). Can microfluidics be used to create a more realistic in vitro model of the vaginal ectocervix to better understand bacterial vaginosis?. Houlden, A. and Mackay, R. (2022) 'Can microfluidics be used to create a more realistic in vitro model of the vaginal ectocervix to better understand bacterial vaginosis?' Sexually Transmitted Infections, 98, pp. 74 - 74 (1). doi: 10.1136/sextrans-2021-055225.
NEW
Stamatiou, K. and Vagnarelli, P. (2021). Chromosome Clustering in mitosis by the nuclear protein Ki-67. Stamatiou, K. and Vagnarelli, P. (2021) 'Chromosome Clustering in mitosis by the nuclear protein Ki-67;, Biochemical Society Transactions, 49 (6), pp. 2767 - 2776 (10). doi: 10.1042/BST20210717.
NEW
Arede, L., Foerner, E., Wind, S., ..., Pina, C. et al. (2021). KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia. Arede, L., Foerner, E., Sterre Wind, S., Kulkarni, R., Domingues, A.F., Giotopoulos, G., Kleinwächter,S., Mollenhauer-Starkl, M., Davison, H., Chandru, A., Asby, R., Samarista, R., Gupta, S., Forte, D., Curti, A., Scheer, E., James, B., Huntly, P., Tora, L. and Pina, C. (2022) 'KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia', Blood Advances, 6 (1), pp. 165 - 180 (16). doi: 10.1182/bloodadvances.2020002842.
NEW
Slijepcevic, P. and Wickramasinghe, C. (2021). Reconfiguring SETI in the microbial context: Panspermia as a solution to Fermi's paradox. BioSystems, 206, 104441, pp. 1 - 8. doi: 10.1016/j.biosystems.2021.104441.
NEW
Schmidt, A., Hunt, N., Gordillo-Marañón, M., ..., Drenos, F. et al. (2021). Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease. Nature Communications, 12, 5640, pp. 1-10. doi: 10.1038/s41467-021-25703-3.
NEW
Brooke-Hollidge, A., Conway, J. and Lewis, A. (2021). Gender Differences in Non-Cystic Fibrosis Bronchiectasis Severity and Bacterial Load: The Potential Role of Hormones. Brooke-Hollidge, A., Conway, J. and Lewis, A. (2021) ‘Gender differences in non-cystic fibrosis bronchiectasis severity and bacterial load: the potential role of hormones’, Therapeutic Advances in Respiratory Disease, 15, pp. 1-9. doi: 10.1177/17534666211035311.
NEW
Bastiani, I., McMahon, S., Turner, P., Redmond, K., McGarry, C., Cole, A., O'Sullivan, J., Prise, K., Ainsbury, L. and Anderson, R. (2021). Dose estimation after a mixed field exposure: Radium-223 and intensity modulated radiotherapy. Bastiani, I. et al. (2022) 'Dose estimation after a mixed field exposure: Radium-223 and intensity modulated radiotherapy', Nuclear Medicine and Biology, 106-107, pp. 10 - 20. doi: 10.1016/j.nucmedbio.2021.12.002.
NEW
Drenos, F. (2021). Systems epidemiology of metabolomics measures reveals new relationships between lipoproteins and other small molecules. Drenos, F. (2022) 'Systems epidemiology of metabolomics measures reveals new relationships between lipoproteins and other small molecules', Metabolomics 18, 1, pp. 1-11. doi: 10.1007/s11306-021-01856-6.
NEW
Lewis, A., Philip, EJ, P, Lound, A., Cave, P., Russell, J. and Hopkinson, N. (2021). The physiology of singing and implications for 'Singing for Lung Health' as a therapy for individuals with Chronic Obstructive Pulmonary Disease. BMJ Open Respiratory Research 8, e000996, pp. 1 - 7. doi: 10.1136/bmjresp-2021-000996.
NEW
Lewis, A., Pavitt, M., Buttery, S., Fernandez, B., Mikus-Lelinska, M., Banya, W., Feelisch, M., Polkey, M. and Hopkinson, N. (2021). Dietary nitrate supplementation to enhance exercise capacity in hypoxic COPD: EDEN-OX a double-blind, placebo-controlled, randomised crossover study. Pavitt, M.J. et al. (2022) 'Dietary nitrate supplementation to enhance exercise capacity in hypoxic COPD: EDEN-OX, a double-blind, placebo-controlled, randomised cross-over study', Thorax, 77 (10), pp. 968 - 975 (+ 15 suppl. pp.). doi: 10.1136/thoraxjnl-2021-217147
NEW
Philip, K., Lewis, A., Buttery, S., McCabe, C., Fancourt, D., Orton, C., Polkey, M. and Hopkinson, N. (2021). Aerosol transmission of SARS-CoV-2: inhalation as well as exhalation matters. American Journal of Respiratory and Critical Care Medicine, 203 (8), pp. 1041 - 1042. doi: 10.1164/rccm.202012-4445LE.
NEW
Lewis, A., Knight, E., Bland, M., Middleton, J., Mitchell, E., McCrum, K., Conway, J. and Bevan-Smith, E. (2021). The feasibility of an online platform delivery of pulmonary rehabilitation for individuals with chronic respiratory disease. BMJ Open Respiratory Research, 8, e000880, pp. 1-8. doi:10.1136/bmjresp-2021-000880.
NEW
Trinh, A. and Esposito, A. (2021). Biochemical resolving power of fluorescence lifetime imaging: untangling the roles of the instrument response function and photon-statistics. Biomedical Optics Express, 12 (7), 428070, pp. 3775 - 3788. doi: 10.1364/BOE.428070.
NEW
Roa-Díaz, Z., Asllanaj, E., Amin, H., ..., Drenos, F. et al. (2021). Age at natural menopause and blood pressure traits: Mendelian randomization study. Roa-Díaz, Z.M., Asllanaj, E., Amin, H.A., Rojas, L.Z., Nano, J., Ikram, M.A., Drenos, F., Franco, O.H., Pazoki R., Marques-Vidal, P., Voortman, T. and Muka, T. (2021) ‘Age at Natural Menopause and Blood Pressure Traits: Mendelian Randomization Study’, Journal of Clinical Medicine, 10 (19), 4299, pp. 1-13. doi:10.3390/jcm10194299.
NEW
Born, J., Beymer, D., Rajan, D., ..., Karteris, E. et al. (2021). On the role of artificial intelligence in medical imaging of COVID-19. Patterns, 2 (6), pp. 1 - 18. doi: 10.1016/j.patter.2021.100269.
NEW
Liu, Y., Elsworth, B., Erola, P., Haberland, V., Hemani, G., Lyon, M., Zheng, J., Lloyd, O., Vabistsevits, M. and Gaunt, T. (2021). Erratum: EpiGraphDB: A database and data mining platform for health data science (Bioinformatics (2020) DOI: 10.1093/bioinformatics/btaa961). Bioinformatics, 37 (2), pp. 288 - 288. doi: 10.1093/bioinformatics/btab104.
NEW
Amin, H. and Drenos, F. (2021). No evidence that vitamin D is able to prevent or affect severity of COVID-19 in individuals with European ancestry: A Mendelian randomisation study of open data. BMJ Nutrition, Prevention & Health, 4 (1), pp. 42 - 48 (7) + suppl. doi: 10.1136/bmjnph-2020-000151.
NEW
Lau, D., McLean, M., Priest, A., ..., Lewis, A. et al. (2021). Multiparametric MRI of early tumor response to immune checkpoint blockade in metastatic melanoma. Journal for ImmunoTherapy of Cancer, 9 (9), e003125, pp. 1 - 14. doi: 10.1136/jitc-2021-003125.
NEW
Saravi, S., Alizzi, Z., Tosi, S., Hall, M. and Karteris, E. (2021). Preclinical Studies on the Effect of Rucaparib in Ovarian Cancer: Impact of Brca2 Status. Saravi, S., Alizzi, Z., Tosi, S., Hall, M. and Karteris, E. (2021) ‘Preclinical Studies on the Effect of Rucaparib in Ovarian Cancer: Impact of BRCA2 Status’, Cells, 10(9), 2434, pp. 1-13. doi: 10.3390/cells10092434.
NEW
Lewis, A., Conway, J., Middleton, J., Startup, C. and Wyatt, J. (2021). Playing the Harmonica with Chronic Obstructive Pulmonary Disease. A qualitative study. medRxiv 2021.08.01.21261448, pp. 1-22. doi: 10.1101/2021.08.01.21261448.
NEW
Barravecchia, I., De Cesari, C., Forcato, M., ..., Bridger, J. et al. (2021). Microgravity and space radiation inhibit autophagy in human capillary endothelial cells, through either opposite or synergistic effects on specific molecular pathways. Barravecchia, I. et al. (2022) 'Microgravity and space radiation inhibit autophagy in human capillary endothelial cells, through either opposite or synergistic effects on specific molecular pathways', Cellular and Molecular Life Sciences, 79, 28, pp. 1 - 29. doi: 10.1007/s00018-021-04025-z.
NEW
Cullen, S., Mackay, R., Mohagheghi, A. and Du, X. (2021). The use of smartphone photogrammetry to digitise transtibial sockets: Optimisation of method and quantitative evaluation of suitability. Cullen, S. et al. (2021) ‘The Use of Smartphone Photogrammetry to Digitise Transtibial Sockets: Optimisation of Method and Quantitative Evaluation of Suitability’, Sensors, 21 (24), 8405, pp. 1 - 16. doi: 10.3390/s21248405.
NEW
Lepore, A., Choy, P., Lee, N., ..., Bubici, C. et al. (2021). Phosphorylation and stabilization of PIN1 by JNK promote intrahepatic cholangiocarcinoma growth. Hepatology, 74 (5), pp. 2561 - 2579. doi: 10.1002/hep.31983.
NEW
Katopodis, P., Randeva, H., Spandidos, D., Saravi, S., Kyrou, I. and Karteris, E. (2021). Host cell entry mediators implicated in the cellular tropism of SARS‑CoV‑2, the pathophysiology of COVID‑19 and the identification of microRNAs that can modulate the expression of these mediators (Review). Katopodis, P., Randeva, H.S., Spandidos, D.A., Saravi, S., Kyrou, I. and Karteris, E. (2022) 'Host cell entry mediators implicated in the cellular tropism of SARS‑CoV‑2, the pathophysiology of COVID‑19 and the identification of microRNAs that can modulate the expression of these mediators (Review)', International Journal of Molecular Medicine, 49 (2), 20, pp. 1-12. doi: 10.3892/ijmm.2021.5075.
NEW
Papa, S., Bubici, C. and Syn, W. (2021). STARD1: a new rising StAR in cholesterol-mediated hepatocarcinogenesis. Papa S, Bubici C, Syn WK. STARD1: a new rising StAR in cholesterol-mediated hepatocarcinogenesis. HepatoBiliary Surg Nutr 2021;10(6):910-912. doi: 10.21037/ hbsn-21-374
NEW
Erady, C., Boxall, A., Puntambekar, S., ..., Pina, C. et al. (2021). Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions. npj Genomic Medicine, 6 (1), pp. 1-17. doi: 10.1038/s41525-020-00167-4.
NEW
Gupta, S., Dovey, O., Domingues, A., ..., Hernandez, V., Pina, C. et al. (2021). Transcriptional variability accelerates pre-leukemia by cell diversification and 2 perturbation of protein synthesis. Gupta, S., Dovey, O.M., Domingues, A.F., Cyran, O.W., Cash, C.M., Giotopoulos, G., Rak, J., Cooper, J., Gozdecka, M., Asby, R.J., Al-Jabery, N., Hernandez, V., Prabakaran, S., Huntly, B.J., Vassiliou, G.S. and Pina C. (2021) biorXiv preprint, 2021.10.18.464824, pp. 1-15. doi: 10.1101/2021.10.18.464824.
NEW
Zahra, A., Dong, Q., Hall, M., Jeyaneethi, J., Silva, E., Karteris, E. and Sisu, C. (2021). Identification of Potential Bisphenol A (BPA) Exposure Biomarkers in Ovarian Cancer. Zahra, A., Dong, Q., Hall, M., Jeyaneethi, J., Silva, E., Karteris, E. and Sisu, C. (2021) ‘Identification of Potential Bisphenol A (BPA) Exposure Biomarkers in Ovarian Cancer’, Journal of Clinical Medicine, 10(9), 1979, pp. 1-20. doi: 10.3390/jcm10091979.
NEW
Sales Gil, R., Kommer, D., de Castro, I., Amin, H., Vinciotti, V., Sisu, C. and Vagnarelli, P. (2021). Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression. EMBO reports, 22 (11), e52061, pp. 1-18. doi: 10.15252/embr.202052061.
NEW
Gordillo-Marañón, M., Zwierzyna, M., Charoen, P., ..., Drenos, F. et al. (2021). Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics. Nature Communications, 12, 6120, pp. 1-12. doi: 10.1038/s41467-021-25731-z.
NEW
O’Cathail, S., Wu, C., Thomas, R., Hawkins, M., Maughan, T. and Lewis, A. (2021). NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch. O’Cathail, S. M., Wu, C.-H., Thomas, R., Hawkins, M. A., Maughan, T. S. and Lewis, A. (2021) ‘NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch’, Antioxidants, 10 (9), 1380, pp. 1-14. doi: 10.3390/antiox10091380.
NEW
Frankish, A., Diekhans, M., Jungreis, I., ..., Sisu, C. et al. (2021). GENCODE 2021. Nucleic acids research, 2021, 49 (D1), pp. D916 - D923 doi: 10.1093/nar/gkaa1087
NEW
Zhang, B., Gleadall, A., Belton, P., Mcdonagh, T., Bibb, R. and Qi, S. (2021). New insights into the effects of porosity, pore length, pore shape and pore alignment on drug release from extrusionbased additive manufactured pharmaceuticals. Additive Manufacturing, 2021, 46, 102196, pp. 1 - 18. doi: 10.1016/j.addma.2021.102196.
NEW
Roupakia, E., Chavdoula, E., Karpathiou, G., ..., Karteris, E. et al. (2021). Canonical NF-κB promotes lung epithelial cell tumour growth by downregulating the metastasis suppressor CD82 and enhancing epithelial-to-mesenchymal cell transition. Roupakia, E., Chavdoula, E., Karpathiou, G., Vatsellas, G., Chatzopoulos, D., Mela, A., Gillette, J.M., Kriegsmann, K., Kriegsmann, M., Batistatou, A., Goussia, A., Marcu, K.B., Karteris, E., Klinakis, A. and Kolettas, E. (2021) ‘Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition’, Cancers. MDPI AG, 13 (17), 4302, pp. 1-26. doi: 10.3390/cancers13174302.
NEW
Costa, J., Mackay, R., de Aguiar Greca, S., Corti, A., Silva, E., Karteris, E. and Ahluwalia, A. (2021). The Role of the 3Rs for Understanding and Modeling the Human Placenta. Costa, J., Mackay, R., de Aguiar Greca, S.-C., Corti, A., Silva, E., Karteris, E. and Ahluwalia, A. (2021) ‘The Role of the 3Rs for Understanding and Modeling the Human Placenta’, Journal of Clinical Medicine, 10 (15), 10(15), 3444, pP. 1-xx. doi: 10.3390/jcm10153444.
NEW
Kyrou, I., Randeva, H., Spandidos, D. and Karteris, E. (2021). Not only ACE2—the quest for additional host cell mediators of SARS-CoV-2 infection: Neuropilin-1 (NRP1) as a novel SARS-CoV-2 host cell entry mediator implicated in COVID-19. Signal Transduction and Targeted Therapy, 6 (1), 21, pp. 1-3. doi: 10.1038/s41392-020-00460-9.
NEW
Katopodis, P., Kerslake, R., Davies, J., ..., Karteris, E. et al. (2021). COVID‑19 and SARS‑CoV‑2 host cell entry mediators: Expression profiling of TMRSS4 in health and disease. International Journal of Molecular Medicine, 47 (4), 64, pp. 1-7. doi: 10.3892/ijmm.2021.4897.
NEW
Kassotis, C., Hoffman, K., Völker, J., ..., Ermler, S. et al. (2021). Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study. Toxicology, 461, 152900, pp. 1-13. doi: 10.1016/j.tox.2021.152900.
NEW
Mehta, I., Riyahi, K., Torres Pereira, R., Meaburn, K., Figgitt, M., Kill, I., Eskiw, C. and Bridger, J. (2021). Interphase Chromosomes in Replicative Senescence: chromosome positioning as a senescence biomarker and the lack of nuclear motor-driven chromosome repositioning in senescent cells. Frontiers in Cell and Developmental Biology, 9, 640200, pp. 1-18. doi: 10.3389/fcell.2021.640200.
NEW
Federico, C., Bruno, F., Ragusa, D., Clements, C., Brancato, D., Henry, M., Bridger, J., Tosi, S. and Saccone, S. (2021). Chromosomal Rearrangements and Altered Nuclear Organization: Recent Mechanistic Models in Cancer. Federico, C., Bruno, F., Ragusa, D., Clements, C. S., Brancato, D., Henry, M. P., Bridger, J. M., Tosi, S. and Saccone, S. (2021) ‘Chromosomal Rearrangements and Altered Nuclear Organization: Recent Mechanistic Models in Cancer’, Cancers, 13 (22), 5860, pp. 1-13. doi: 10.3390/cancers13225860.
NEW
Garner, J., Biddiscombe, M., Meah, S., Lewis, A., Buttery, S., Hopkinson, N., Kemp, S., Usmani, O., Shah, P. and Verbanck, S. (2021). Endobronchial Valve Lung Volume Reduction and Small Airways Function. Garner J, Biddiscombe MF, Meah S, Lewis A, Buttery SC, Hopkinson NS, Kemp SV, Usmani OS, Shah PL, Verbanck S. Endobronchial Valve Lung Volume Reduction and Small Airways Function. American Journal of Respiratory and Critical Care Medicine. doi: 10.1164/rccm.202010-3939le
NEW
Osório, L., Silva, E. and Mackay, R. (2021). A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip (OOAC) Systems. Osório, L. A., Silva, E. and Mackay, R. E. (2021) ‘A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip (OOAC) Systems’, Bioengineering, 8(8), 113, p. 1-.31 doi: 10.3390/bioengineering8080113.
NEW
Sirunyan, A., Tumasyan, A., Adam, W., ..., Tosi, S. et al. (2021). Measurements of pp -> ZZ production cross sections and constraints on anomalous triple gauge couplings at root s=13 TeV. Sirunyan, A.M., Tumasyan, A., Adam, W. et al. Measurements of pp→ZZ production cross sections and constraints on anomalous triple gauge couplings at s√=13TeV. Eur. Phys. J. C 81, 200 (2021). https://doi.org/10.1140/epjc/s10052-020-08817-8
NEW
Azizi Machekposhti, S., Zhang, B., Sachan, R., Vanderwal, L., Stafslien, S. and Narayan, R. (2021). Patterned surfaces with the controllable drug doses using inkjet printing. Journal of Materials Research, 36 (19), pp. 3865 - 3876. doi: 10.1557/s43578-021-00135-3.
NEW
Zagkos, L., Drenos, F., Emmett, P., Blakemore, A., Nordstrom, T., Hurtig, T., Jarvelin, M. and Dovey, T. (2021). Adolescents’ dietary habits and meal patterns influence school performance in the Northern Finland Birth Cohort 1986: mendelian randomisation study. Zagkos L, Drenos F, Emmett P, Blakemore AI, Nordstrom T, Hurtig T, Jarvelin MR, Dovey TM. Adolescents’ dietary habits and meal patterns influence school performance in the Northern Finland Birth Cohort 1986: mendelian randomisation study. bioRxiv. 2021 Jan 1. doi: 10.1101/2021.04.30.442179
NEW
Zhang, B., Nasereddin, J., McDonagh, T., von Zeppelin, D., Gleadall, A., Alqahtani, F., Bibb, R., Belton, P. and Qi, S. (2021). Effects of porosity on drug release kinetics of swellable and erodible porous pharmaceutical solid dosage forms fabricated by hot melt droplet deposition 3D printing. Zhang, B. et al. (2021) ‘Effects of porosity on drug release kinetics of swellable and erodible porous pharmaceutical solid dosage forms fabricated by hot melt droplet deposition 3D printing’, International Journal of Pharmaceutics. 604, 120626, pp.1-11. https://doi.org/10.1016/j.ijpharm.2021.120626.
NEW
Vagnarelli, P. (2021). Back to the new beginning: Mitotic exit in space and time. Seminars in Cell & Developmental Biology, 117, pp. 140 - 148. doi: 10.1016/j.semcdb.2021.03.010
NEW
Gulino, G., Bruno, F., Sturiale, V., Brancato, D., Ragusa, D., Tosi, S., Saccone, S. and Federico, C. (2021). From FISH to Hi-C: the chromatin architecture of the chromosomal region 7q36.3, frequently rearranged in leukemic cells, is evolutionary conserved. Gulino, G. M., Bruno, F., Sturiale, V., Brancato, D., Ragusa, D., Tosi, S., Saccone, S. and Federico, C. (2021) ‘From FISH to Hi-C: The Chromatin Architecture of the Chromosomal Region 7q36.3, Frequently Rearranged in Leukemic Cells, Is Evolutionary Conserved’, International Journal of Molecular Sciences, 22(5), 2338, pp. 1-16. doi: 10.3390/ijms22052338.
NEW
Suleman, S., Schrubaji, K., Filippou, C., Ignatova, S., Hewitson, P., Huddleston, J., Karda, R., Waddington, S. and Themis, M. (2021). Rapid and inexpensive purification of adenovirus vectors using an optimised aqueous two-phase technology. Suleman, S., Schrubaji, K., Filippou, C., Ignatova, S., Hewitson, P., Huddleston, J., Karda, R., Waddington, S.N. and Themis, M. (2022) 'Rapid and inexpensive purification of adenovirus vectors using an optimised aqueous two-phase technology', Journal of Virological Methods, 299, 114305, pp. 1-9. doi: 10.1016/j.jviromet.2021.114305.
NEW
Collett, G., Young, W., Martin, W. and Anderson, R. (2021). Exposure Worry: The Psychological Impact of Perceived Ionizing Radiation Exposure in British Nuclear Test Veterans. Collett, G., Young, W.R., Martin, W. and Anderson, R.M. (2021) ‘Exposure Worry: The Psychological Impact of Perceived Ionizing Radiation Exposure in British Nuclear Test Veterans’, International Journal of Environmental Research and Public Health, 18 (22), 12188, pp. 1-xx. doi: 10.3390/ijerph182212188.
NEW
Scott, D., Francis-Newton, N., Marsh, M., ..., Esposito, A. et al. (2021). A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death. Cell Chemical Biology, 28 (6), pp. 835 - 847 (+ e1 - e5). doi: 10.1016/j.chembiol.2021.02.006.
NEW
Suleman, S., Payne, A., Bowden, J., ..., Themis, M. et al. (2022). HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival. Gene Therapy, 29 (12), pp. 720 - 729 (10). doi: 10.1038/s41434-022-00335-4.
NEW
Suleman, S., Payne, A., Bowden, J., ..., Themis, M. et al. (2022). HIV-1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival. Human Gene Therapy, 33 (23-24), pp. A48 - A48. doi: 10.1089/hum.2022.29225.abstracts.
NEW
Karkia, R., Wali, S., Payne, A., Karteris, E. and Chatterjee, J. (2022). Diagnostic Accuracy of Liquid Biomarkers for the Non-Invasive Diagnosis of Endometrial Cancer: A Systematic Review and Meta-Analysis. Cancers, 2022, 14 (19), pp. 1 - 28. doi: 10.3390/cancers14194666.
NEW
Payoe, S., Safa, A., Payne, A. and Stenbeck, G. (2022). Identification of differentially expressed immune receptor genes in osteosarcoma. Bone Reports, 16 (Supplement), 101489, pp. 78 - 78. doi: 10.1016/j.bonr.2022.101489.
NEW
Perera, M., Suleman, S., Al Haque, S., ..., Payne, A., Themis, M. et al. (2022). Development of a human-based platform to assess adeno-associated viral vector genotoxicity. Human Gene Therapy, 33 (23-24), pp. A39 - A40. doi: 10.1089/hum.2022.29225.abstracts.
NEW
Burmi, R., Box, G., Wazir, U., Hussain, H., Davies, J., William, C., Eccles, S., Jiang, W., Mokbel, K. and Harvey, A. (2022). Breast Tumour Kinase (Brk/PTK6) Contributes to Breast Tumour Xenograft Growth and Modulates Chemotherapeutic Responses In Vitro. Genes, 13, 402, pp. 1 - 13.. doi: 10.3390/genes13030402.
NEW
Houghton-Gisby, J., Kerslake, R., Karteris, E., Mokbel, K. and Harvey, A. (2022). ACBD3 bioinformatic analysis and protein expression in breast cancer cells. International Journal of Molecular Sciences. 23 (16), 8881, pp. 1 - 22. doi: 10.3390/ijms23168881.
NEW
Ermler, S. and Kortenkamp, A. (2022). Declining semen quality and polybrominated diphenyl ethers (PBDEs): Review of the literature to support the derivation of a reference dose for a mixture risk assessment. Ermler, S. and Kortenkamp, A. (2022) ‘Declining semen quality and polybrominated diphenyl ethers (PBDEs): Review of the literature to support the derivation of a reference dose for a mixture risk assessment’, International Journal of Hygiene and Environmental Health, 242, 113953, pp. 1-10. doi: 10.1016/j.ijheh.2022.113953.
NEW
Lewis, A., Kal, E., Nolan, C., Cave, P., Grillo, L., Conway, J. and Jones, M. (2022). Pilot study of physiotherapist-led versus music therapist-led breathing control exercises for young adults living with breathing pattern disorder: a randomised controlled trial protocol. BMJ Open Respiratory Research, 9, e001414, pp. 1 - 7. doi: 10.1136/bmjresp-2022-001414.
NEW
Steele, E., Gorczynski, R., Lindley, R., ..., Slijepcevic, P. et al. (2022). Overview SARS-CoV-2 Pandemic as January-February 2022: Likely Cometary Origin, Global Spread, Prospects for Future Vaccine Efficacy. Infectious Diseases and Therapeutics, 3 (1), pp. 260 - 275. doi: 10.31038/IDT.2022311.
NEW
Valls, P. and Esposito, A. (2022). Signalling dynamics, cell decisions, and homeostatic control in health and disease. Current Opinion in Cell Biology, 75, 102066, pp. 1 - 9. doi: 10.1016/j.ceb.2022.01.011.
NEW
Lewis, A. and Osadnik, C. (2022). changing practice by changing pressures: A role for oscillating positive expiratory pressure in chronic obstructive pulmonary disease. Thorax, 78 (2), pp. 113 - 115. doi: 10.1136/thorax-2022-219451.
NEW
Bridger, J., Torres Pereira, R., Pina, C., Tosi, S. and Lewis, A. (2022). Alterations to Genome Organisation in Stem Cells, their Differentiation and Associated Diseases. in: Kloc, M. and Kubiak, J.Z. (eds.) Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine (Results and Problems in Cell Differentiation, vol. 70). Cham, Switzerland: Springer Nature, pp. 71 - 102. doi: 10.1007/978-3-031-06573-6_3.
NEW
Lewis, A., Conway, J., Middleton, J., Startup, C. and Wyatt, J. (2022). Playing the Harmonica with Chronic Obstructive Pulmonary Disease. A qualitative study. Chronic Respiratory Disease, 19 (1), pp. 1-9. doi: 10.1177/14799731221083315.
NEW
Frankish, A., Carbonell-Sala, S., Diekhans, M., ..., Sisu, C. et al. (2022). GENCODE: reference annotation for the human and mouse genomes in 2023. Frankish, A. et al. (2023) 'GENCODE: reference annotation for the human and mouse genomes in 2023', Nucleic acids research, 51 (D1), pp. D942 - D949. doi: 10.1093/nar/gkac1071.
NEW
Meier, S., Seddon, J., Maasdorp, E., ..., Roberts, T. et al. (2022). Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis. PLoS ONE, 17 (12), e0278295, pp. 1 - 24. doi: 10.1371/journal.pone.0278295.
NEW
Rake, C., Gilham, C., Scholze, M., Bukasa, L., Stephens, J., Simpson, J., Peto, J. and Anderson, R. (2022). British nuclear test veteran family trios for the study of genetic risk. Journal of Radiological Protection, 42, 021528, pp. 1-11. doi: 10.1088/1361-6498/ac6e10.
NEW
Buhigas, C., Warren, A., Leung, W., ..., Haberland, V. et al. (2022). The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates. Molecular Cancer, 21 (1), 183, pp. 1 - 13. doi: 10.1186/s12943-022-01644-3.
NEW
Gomes, S., Baltazar, F., Silva, E. and Preto, A. (2022). Microbiota-Derived Short-Chain Fatty Acids: New Road in Colorectal Cancer Therapy. Gomes S. et. al.(2022) 'Microbiota-Derived Short-Chain Fatty Acids: New Road in Colorectal Cancer Therapy' in Pharmaceutics, 14 (11), 2359, pp. 1 - 22. doi: 10.3390/pharmaceutics14112359.
NEW
Kerslake, R., Randeva, H., Jonigk, D., Werlein, C., Robertus, J., Katopodis, P., Jasker, P., Spandidos, D., Kyrou, I. and Karteris, E. (2022). Protein expression of transmembrane protease serine 4 in the gastrointestinal tract and in healthy, cancer, and SARS‑CoV‑2 infected lungs. Molecular medicine reports, 25 (4), 138, pp. 1 - 6. doi: 10.3892/mmr.2022.12654.
NEW
Zhang, B., Mi, Y., Zhang, L., Zhang, Y., Li, M., Zhai, Q. and Li, M. (2022). Dynamic Community Detection Method of a Social Network Based on Node Embedding Representation. Mathematics, 10 (24), 4738, pp. 1 - 22. doi: 10.3390/math10244738.
NEW
Steinmann, J., Lewis, A., Ellmers, T., Jones, M., MacBean, V. and Kal, E. (2022). The validity and reliability of the Breathing Vigilance Questionnaire (Breathe-VQ). Thorax, 77 (Suppl 1), pp. A12 - A13. doi: 10.1136/thorax-2022-BTSabstracts.19.
NEW
Shabir, K., Gharanei, S., Orton, S., Patel, V., Chauhan, P., Karteris, E., Randeva, H., Brown, J. and Kyrou, I. (2022). Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway. Shabir, K. et al. (2023) 'Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway', International Journal of Molecular Sciences, 24 (1), 227, pp. 1 - 16. doi: 10.3390/ijms24010227.
NEW
Wang, R., Lei, T., Cui, R., Zhang, B., Meng, H. and Nandi, A. (2022). Medical Image Segmentation Using Deep Learning: A Survey. IET Image Processing, 16 (5), pp. 1243 - 1267. doi: 10.1049/ipr2.12419.
NEW
Abascal, F., Acosta, R., Addleman, N., ..., Sisu, C. et al. (2022). Author Correction: Perspectives on ENCODE (Nature, (2020), 583, 7818, (693-698), 10.1038/s41586-020-2449-8). Nature, 605 (7909), E4, pp.1 - 1. doi: 10.1038/s41586-021-04213-8.
NEW
Abdelhalim, M., Patel, A., Moquet, J., Saha, P., Smith, A., Badie, C., Anderson, R., Ainsbury, E. and Modarai, B. (2022). A higher incidence of chromosomal aberrations in operators performing a large volume of endovascular procedures. Abdelhalim, M.A., Patel, A., Moquet, J., Saha, P., Smith, A., Badie, C., Anderson, R., Ainsbury, E.A., and Modarai, B. (2022). 'A higher incidence of chromosomal aberrations in operators performing a large volume of endovascular procedures', Circulation., 145 (24), pp. 1808-1810. doi: 10.1161/CIRCULATIONAHA.121.058139.
NEW
Ragusa, D., Suen, C., Torregrosa, G., ..., Pina, C. et al. (2022). Haemogenic Gastruloids Recapitulate Developmental Haematopoiesis and Provide an Ontogeny-Relevant Context to Dissect the Origins of Infant Leukemia. Blood, 140 (Supplement 1), pp. 1684 - 1685. doi: 10.1182/blood-2022-169733.
NEW
Zagkos, L., Dib, M., Pinto, R., ..., Drenos, F. et al. (2022). Associations of genetically predicted fatty acid levels across the phenome: A mendelian randomisation study. PLoS Medicine, 19 (12), e1004141, pp. 1 - 20. doi: 10.1371/journal.pmed.1004141.
NEW
Nsamba, J., Eroju, P., Drenos, F. and Mathews, E. (2022). Body Composition Characteristics of Type 1 Diabetes Children and Adolescents: A Hospital-Based Case-Control Study in Uganda. Children, 9 (11), 1720, pp. 1 - 12. doi: 10.3390/children9111720.
NEW
Suleman, S., Fawaz, S., Roberts, T., Bigger, B., Ellison, S. and Themis, M. (2022). An optimised protocol to generate high titre lentiviral vectors by extended HEK293T culture following transient transfection and suspension culture. Human Gene Therapy, 33 (23-24), pp. A103 - A103. doi: 10.1089/hum.2022.29225.abstracts
NEW
Nsamba, J., Nabirye, G., Hense, S., Drenos, F. and Mathews, E. (2022). Lived Experiences of Newly Diagnosed Type 1 Diabetes Mellitus Children and Adolescents in Uganda. Journal of Multidisciplinary Healthcare, 15, pp. 2647 - 2665. doi: 10.2147/jmdh.s389265.
NEW
Grillo, L., Lewis, A., Shannon, H. and Russell, A. (2022). Physiotherapists’ opinions of the physiotherapy assessment of Breathing Pattern Dysfunction: a qualitative study. Thorax, 77 (Suppl. 1), pp. A13 - A13. doi: 10.1136/thorax-2022-BTSabstracts.20.
NEW
Ragusa, D., Tosi, S. and Sisu, C. (2022). Pan-Cancer Analysis Identifies MNX1 and Associated Antisense Transcripts as Biomarkers for Cancer. Cells, 11 (22), 3577, pp. 1 - 21. doi: 10.3390/cells11223577.
NEW
Huguet, F., Gokhan, E., Foster, H., Amin, H. and Vagnarelli, P. (2022). Repo-Man/PP1 SUMOylation mediates binding to lamin A and Serine 22 dephosphorylation. Open Biology, 12 (4), 220017, pp. 1-12. doi: 10.1098/rsob.220017.
NEW
Kerslake, R., Panfilov, S., Mustafa, N., Hall, M., Kyrou, I., Randeva, H., Karteris, E. and Godfrey, R. (2022). Elevated Circulating Lactate Levels and Widespread Expression of Its Cognate Receptor, Hydroxycarboxylic Acid Receptor 1 (HCAR1), in Ovarian Cancer. Journal of Clinical Medicine, 12 (1), 217, pp. 1 - 13. doi: 10.3390/jcm12010217.
NEW
Philip, K., Owles, H., McVey, S., ..., Lewis, A. et al. (2022). An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms following COVID-19: a parallel-group, single-blind, randomised controlled trial. The Lancet Respiratory Medicine, 10 (9), pp. 851 - 862. doi: 10.1016/S2213-2600(22)00125-4.
NEW
Kerslake, R., Belay, B., Panfilov, S., Hall, M., Kyrou, I., Randeva, H., Hyttinen, J., Karteris, E. and Sisu, C. (2022). A Meta-analysis of 2D vs. 3D Ovarian Cancer Cellular Models. bioRxiv, (preprint), pp. 1 - 31. doi: 10.1101/2022.12.05.519144.
NEW
Kerslake, R., Sisu, C., Panfilov, S., Hall, M., Khan, N., Jeyaneethi, J., Randeva, H., Kyrou, I. and Karteris, E. (2022). Differential Regulation of Genes by the Glucogenic Hormone Asprosin in Ovarian Cancer. Journal of Clinical Medicine, 11 (19), 5942, pp. 1 - 18. doi: 10.3390/jcm11195942.
NEW
Kortenkamp, A., Martin, O., Ermler, S., Baig, A. and Scholze, M. (2022). Bisphenol A and declining semen quality: A systematic review to support the derivation of a reference dose for mixture risk assessments. Journal of Hygiene and Environmental Health, 241, 113942, pp. 1 - 12. doi: 10.1016/j.ijheh.2022.113942.
NEW
Ragusa, D., Suen, C., Torregrosa Cortes, G., ..., Pina, C. et al. (2022). Dissecting infant leukemia developmental origins with a hemogenic gastruloid model. bioRxiv, [preprint]. 2022.10.07.511362, pp. 1 - 43. doi: 10.1101/2022.10.07.511362.
NEW
Ragusa, D., Cicirò, Y., Federico, C., Saccone, S., Bruno, F., Saeedi, R., Sisu, C., Pina, C., Sala, A. and Tosi, S. (2022). Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles. Oncogenesis, 11 (1), 50, pp. 1-7. doi: 10.1038/s41389-022-00426-2.
NEW
Gupta, S., Dovey, O., Domingues, A., ..., Hernandez, V., Pina, C. et al. (2022). Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis. Science Advances, 8, eabn4886, pp. 1 - 15. doi: 10.1126/sciadv.abn4886.
NEW
Kortenkamp, A., Scholze, M., Ermler, S., Priskorn, L., Jørgensen, N., Andersson, A. and Frederiksen, H. (2022). Combined exposures to bisphenols, polychlorinated dioxins, paracetamol, and phthalates as drivers of deteriorating semen quality. Environment International, 165, 107322, pp. 1 - 14. doi: 10.1016/j.envint.2022.107322.
NEW
Gharanei, S., Ramanjaneya, M., Patel, A., Patel, V., Shabir, K., Auld, C., Karteris, E., Kyrou, I. and Randeva, H. (2022). NUCB2/Nesfatin-1 Reduces Obesogenic Diet Induced Inflammation in Mice Subcutaneous White Adipose Tissue. Nutrients, 2022, 14 (7), 1409, pp. 1-17. doi: 10.3390/nu14071409.
NEW
Jiang, X., Anasanti, M., Drenos, F., Blakemore, A. and Pazoki, R. (2022). Urinary Sodium Excretion Enhances the Effect of Alcohol on Blood Pressure. Jiang, X., Anasanti, M.D., Drenos, F., Blakemore, A.J. and Pazoki, R. (2022) ''Urinary Sodium Excretion Enhances the Effect of Alcohol on Blood Pressure, Healthcare, 10 (7), 1296, pp. 1 - 13. doi: 10.3390/healthcare10071296.
NEW
Panraksa, P., Zhang, B., Rachtanapun, P., Jantanasakulwong, K., Qi, S. and Jantrawut, P. (2022). ‘Tablet-in-Syringe’: A Novel Dosing Mechanism for Dysphagic Patients Containing Fast-Disintegrating Tablets Fabricated Using Semisolid Extrusion 3D Printing. Pharmaceutics, 14 (2), 443, pp. 1-18. doi: 10.3390/pharmaceutics14020443.
NEW
Filipe, A., Chudasama, D., Kerslake, R., Jeyaneethi, J., Anikin, V., Kyrou, I., Randeva, H., Sisu, C., Hall, M. and Karteris, E. (2022). Differential Expression of RAD51AP1 in Ovarian Cancer: Effects of siRNA In Vitro. Journal of Personalized Medicine, 12 (2), 201, pp. 1-13. doi: 10.3390/jpm12020201.
NEW
Anas, S., Kyrou, I., Rand-Weaver, M. and Karteris, E. (2022). The effect of online and in-person team-based learning (TBL) on undergraduate endocrinology teaching during COVID-19 pandemic. BMC Medical Education, 22 (1), 120, pp. 1-9. doi: 10.1186/s12909-022-03173-5.
NEW
Zahra, A., Kerslake, R., Kyrou, I., Randeva, H., Sisu, C. and Karteris, E. (2022). Impact of environmentally relevant concentrations of Bisphenol A (BPA) on the gene expression profile in an in vitro model of the normal human ovary. Zahra, A., Kerslake, R., Kyrou, I., Randeva, H.S., Sisu, C. and Karteris. E. (2022) ‘Impact of Environmentally Relevant Concentrations of Bisphenol A (BPA) on the Gene Expression Profile in an In Vitro Model of the Normal Human Ovary’, International Journal of Molecular Sciences, 23(10), 5334, pp. 1 - 14. doi:10.3390/ijms23105334.
NEW
Amin, H., Kaewsri, P., Yiorkas, A., Cooke, H., Blakemore, A. and Drenos, F. (2022). Mendelian randomisation analyses of UK Biobank and published data suggest that increased adiposity lowers risk of breast and prostate cancer. Scientific Reports, 12 (1), 909, pp. 1-10. doi: 10.1038/s41598-021-04401-6.
NEW
Zahra, A., Hall, M., Chatterjee, J., Sisu, C. and Karteris, E. (2022). In Silico Study to predict the structural and functional consequences of SNPs on biomarkers of ovarian cancer (OC) and BPA exposure-associated OC. Zahra, A., Hall, M, Chatterjee, J., Sisu, C. and Karteris, E. (2022) ‘In Silico Study to Predict the Structural and Functional Consequences of SNPs on Biomarkers of Ovarian Cancer (OC) and BPA Exposure-Associated OC’, International Journal of Molecular Sciences, 23 (3), 1725, p. 1-14. doi: 10.3390/ijms23031725.
NEW
Zhang, B., Teoh, X., Yan, J., Gleadall, A., Belton, P., Bibb, R. and Qi, S. (2022). Development of combi-pills using the coupling of semi-solid syringe extrusion 3D printing with fused deposition modelling. Zhang, B. et al. (2022) ‘Development of combi-pills using the coupling of semi-solid syringe extrusion 3D printing with fused deposition modelling’, International Journal of Pharmaceutics, 625, 122140, pp. 1 - 14, doi: 10.1016/j.ijpharm.2022.122140.
NEW
Steinmann, J., Lewis, A., Ellmers, T., Jones, M., MacBean, V. and Kal, E. (2022). Validating the Breathing Vigilance Questionnaire for use in Dysfunctional Breathing. medRxiv, (preprint), pp. 1 - 24. doi:10.1101/2022.07.11.22277501.
NEW
Teoh, X., Zhang, B., Belton, P., Chan, S. and Qi, S. (2022). The Effects of Solid Particle Containing Inks on the Printing Quality of Porous Pharmaceutical Structures Fabricated by 3D Semi-Solid Extrusion Printing. Qi, S. et al. (2022) The Effects of Solid Particle Containing Inks on the Printing Quality of Porous Pharmaceutical Structures Fabricated by 3D Semi-Solid Extrusion Printing. Pharm Res., vol. 39 (6), pp. 1267 - 1279. https://doi.org/10.1007/s11095-022-03299-7
NEW
Moorhouse, A., Scholze, M., Sylvius, N., Gilham, C., Rake, C., Peto, J., Anderson, R. and Dubrova, Y. (2022). No evidence of increased mutations in the germline of a group of British nuclear test veterans. Scientific Reports, 12, 10830, pp. 1-8. doi: 10.1038/s41598-022-14999-w.
NEW
Ermler, S. and Kortenkamp, A. (2022). Systematic review of associations of polychlorinated biphenyl (PCB) exposure with declining semen quality in support of the derivation of reference doses for mixture risk assessments. Ermler, S., Kortenkamp, A. (2022) Systematic review of associations of polychlorinated biphenyl (PCB) exposure with declining semen quality in support of the derivation of reference doses for mixture risk assessments. Environ Health Vol. 21. https://doi.org/10.1186/s12940-022-00904-5
NEW
Karkia, R., MacCarthy, G., Payne, A., Karteris, E., Pazoki, R. and Chatterjee, J. (2025). The Association Between Metabolic Syndrome and the Risk of Endometrial Cancer in Pre- and Post-Menopausal Women: A UK Biobank Study. Journal of Clinical Medicine, 14 (3), 751, pp. 1 - 15. doi: 10.3390/jcm14030751.
NEW
Suleman, S., Alhaque, S., Guo, A., ..., Payne, A., Themis, M. et al. (2025). hInGeTox: a human-based in vitro platform to evaluate lentivirus/host interactions that contribute to genotoxicity. Gene Therapy, 32 (6), pp. 641 - 656. doi: 10.1038/s41434-025-00550-9.
NEW
Ryan, J., Burke, J., Byrne, R., Capellari, E., Harvey, A., O'Connell, N., Omichinski, D., Rodby-Bousquet, E., Peterson, M. and The Adult CP Clinical Practice Guideline Working Group (2025). Pain in adults with cerebral palsy: A systematic review. Developmental Medicine and Child Neurology, 67 (7), pp. 854 - 874. doi: 10.1111/dmcn.16254.
NEW
Tree, D., Harvey, A. and Rand-Weaver, M. (2025). Integrated Programme Assessment: 10 years on. Open Scholarship of Teaching and Learning, 2025, 4 (1), pp. 166 - 180 doi: 10.56230/osotl.128
NEW
Harvey, A. and Tree, D. (2025). From silos to synthesis: ensuring interdisciplinary education through synoptic assessment. Biochemist, 47 (1), pp. 27 - 34. doi: 10.1042/bio_2025_104.
NEW
Kabella, N., Bayer, F., Stamatiou, K., ..., Vagnarelli, P. et al. (2025). Proteomic analyses identify targets, pathways, and cellular consequences of oncogenic KRAS signaling. Science Signaling, 18 (897), eadt6552, pp. 1 - 51. doi: 10.1126/scisignal.adt6552.
NEW
Panraksa, P., Jantrawut, P., Teoh, X., Sengtakdaed, K., Pornngam, P., Chaiwarit, T., Chantadee, T., Jantanasakulwong, K., Udomsom, S. and Zhang, B. (2025). Formulation and Structural Optimisation of PVA-Fibre Biopolymer Composites for 3D Printing in Drug Delivery Applications. Polymers, 17 (18), 2502, pp. 1 - 24. doi: 10.3390/polym17182502.
NEW
Mokbel, R., Kodresko, A., Mokbel, K., Ghazal, H., Trembley, J. and Jouhara, H. (2025). Cutaneous Cryosurgery in Dermatology: Evolving Principles and Clinical Applications for Benign, Premalignant, and Malignant Lesions. Mokbel, R. et al. (2025) ‘Cutaneous Cryosurgery in Dermatology: Evolving Principles and Clinical Applications for Benign, Premalignant, and Malignant Lesions’, In Vivo, 39 (2), pp. 577 - 612. doi: 10.21873/invivo.13865.
NEW
Clarkson, E. and Lewis, A. (2025). BMP antagonist CHRDL2 enhances the cancer stem-cell phenotype and increases chemotherapy resistance in colorectal cancer. Molecular Oncology, 0 (ahead of print), pp. 1 - 21. doi: 10.1002/1878-0261.70064.
NEW
Chen, L., Zhang, Y., Chen, G., Li, J., Zhang, B. and Wang, M. (2025). Influence of typical technological parameters on the processing quality of laser surface texturing technology for finger sealing. Surface Topography: Metrology and Properties, 13 (1), 015008, pp. 1 - 18. doi: 10.1088/2051-672X/ad993e.
NEW
Al-dulaimi, S., Thomas, R., Matta, S. and Roberts, T. (2025). Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity. Biogerontology, 26 (5), 178, pp. 1 - 14. doi: 10.1007/s10522-025-10315-x.
NEW
Payoe, K., Gadar, K., Flahaut, E., McCarthy, R. and Stenbeck, G. (2025). Nanoparticle-induced systemic toxicity and immune response in Galleria mellonella larvae. Frontiers in Pharmacology, 16, 1625472, pp. 1 - 14. doi: 10.3389/fphar.2025.1625472.
NEW
Clarkson, E. and Lewis, A. (2025). BMP signalling in colorectal cancer; the yin to WNTs yang. Journal of Pathology, 266 (3), pp. 280 - 291. doi: 10.1002/path.6428.
NEW
Ahmed, O., Wang, M., Zhang, B., Irving, R., Begg, P. and Du, X. (2025). Robotic Systems for Cochlear Implant Surgeries: A Review of Robotic Design and Clinical Outcomes. Electronics, 14 (13), 2685, pp. 1 - 27. doi: 10.3390/electronics14132685.
NEW
Futema, M., Ingegneri, T., Sharifi, M., Drenos, F. and Humphries, S. (2025). Polygenic predisposition to increased LDL-cholesterol concentration and Carotid Artery Intima Media Thickness in childhood and early adulthood. Atherosclerosis Plus, 62 (Supplement), pp. 3 - 3. doi: 10.1016/j.athplu.2025.10.004.
NEW
Hashimi, M., Amin, H., Day, A. and Drenos, F. (2025). Exploring the causal relationship between vitamin D levels and deficiency with the risk of cataract: A Mendelian Randomisation study. Ophthalmic Research, 0 (ahead of print), pp. 1 - 18. doi: 10.1159/000545332.
NEW
Ber, S., Yang, M., Sciacovelli, M., ..., Esposito, A. et al. (2025). FOXO1 links KRAS G12D and G12V alleles to glutamine and nitrogen metabolism in colorectal cancer. EMBO Reports, 0 (early online), pp. 1 - 21. doi: 10.1038/s44319-025-00641-z.
NEW
Poonawala, K. and Zhang, B. (2025). Influence of 3D printing process parameters and design on mechanical properties of tissue scaffolds. MATEC Web of Conferences, 413, 08003, pp. 1 - 5. doi: 10.1051/matecconf/202541308003.
NEW
Karkia, R., Sisu, C., Saravi, S., Kyrou, I., Randeva, H., Chatterjee, J. and Karteris, E. (2025). Effects of Asprosin and Role of TLR4 as a Biomarker in Endometrial Cancer. Molecules, 30 (16), 3410, pp. 1 - 27. doi: 10.3390/molecules30163410.
NEW
Collinson, R. and Tanos, B. (2025). Primary cilia and cancer: a tale of many faces. Oncogene, 44 (21), pp. 1551 - 1566. doi: 10.1038/s41388-025-03416-x.
NEW
Cullen, S., Mohagheghi, A. and Mackay, R. (2025). Investigating the accuracy of smartphone photogrammetry for remote 3D scanning transtibial amputees. Journal of Medical Engineering and Technology, 0 (ahead of print), pp. 1 - 11. doi: 10.1080/03091902.2025.2540096.
NEW
Zhang, B., da Silva, M., Johnston, I., Aspinall, S. and Cook, M. (2025). Poly(vinyl alcohol)‐Agar Double Network Hydrogels: Linking Formulation to Mechanical and Rheological Properties. Macromolecular Chemistry and Physics, 226 (24), e00257, pp. 1 - 9. doi: 10.1002/macp.202500257.
NEW
Suleman, S., Alhaque, S., Guo, A., Zhang, A., Fawaz, S., Perera, S., Khalifa, M., Rashidi, H., Hay, D. and Themis, M. (2025). Transcriptomic Profiling of iPS Cell-Derived Hepatocyte-like Cells Reveals Their Close Similarity to Primary Liver Hepatocytes. Cells, 14 (12), 925, pp. 1 - 19. doi: 10.3390/cells14120925.
NEW
Filipe, A., Saravi, S., Mustafov, D., ..., Drenos, F., Sisu, C., Karteris, E. et al. (2025). Emerging roles of the cancerous inhibitor of protein phosphatase 2A (CIP2A) in ovarian cancer. Scientific Reports, 15, 22382, pp. 1 - 15. doi: 10.1038/s41598-025-05013-0.
NEW
Sammy, A., Karteris, E., Riyahi, K. and Bridger, J. (2025). Alterations in Interphase Chromosome Positioning and Nuclear Myosin Iβ and VI in Ovarian Cancer Cells, and the Reversal of Cisplatin Chemo resistance upon knock-down of Nuclear Myosin Iβ. Chromosome Research, 0 (in submission).
NEW
James, E., Teh, M., Li, Y., ..., Roberts, T., Lewis, A. et al. (2025). Membrane transporter progressive ankylosis protein homologue (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation, and ageing. Frontiers in Aging, 6, 1583288, pp. 1 - 28. doi: 10.3389/fragi.2025.1583288.
NEW
Esentürk, E., Sahli, A., Haberland, V. et al. (2025). Causes of evolutionary divergence in prostate cancer. arXiv preprint, arXiv:2503.13189v1 [q-bio.GN, pp. 1 - 23. doi: 10.48550/arXiv.2503.13189.
NEW
Suleman, S., Khalifa, M., Fawaz, S., Alhaque, S., Chinea, Y. and Themis, M. (2025). Analysis of HIV-1 based lentiviral vector particle composition by PacBio long-read nucleic acid sequencing. Human Gene Therapy, 0 (accepted, in press), pp. 1 - 9. doi: 10.1089/hum.2024.121.
NEW
Vagnarelli, P. (2025). The 10th Nuclear Envelope and Chromatin Organisation UK meeting. 3–4 October 2024, Brunel University London. Biochemist, 47 (1), pp. 59 - 59. doi: 10.1042/bio_2024_938.
NEW
Kabella, N., Bayer, F., Stamatiou, K., ..., Vagnarelli, P. et al. (2025). Illuminating oncogenic KRAS signaling by multi-dimensional chemical proteomics. bioRxiv preprint, pp. 1 - 27. doi: 10.1101/2025.01.30.635627.
NEW
Daykin, N., Mansfield, L., Meads, C., ..., Payne, A. et al. (2017). What Works for Wellbeing? A systematic review of wellbeing outcomes for music and singing in adults. Daykin N. et al. (2018) 'What works for wellbeing? A systematic review of wellbeing outcomes for music and singing in adults', Perspectives in Public Health, 138 (1), pp. 39 - 46. doi: 10.1177/1757913917740391.
NEW
Thain, A., Silva Vidotto, L., Harvey, A. and Jones, M. (2017). The Prevalence of Dysfunctional Breathing and its Association with Personality Type in a University Population. Thorax 72, pp. A161-A162. doi: 10.1136/thoraxjnl-2017-210983.286.
NEW
Aubert, B., Barate, R., Bona, M., ..., Tosi, S. et al. (2017). Study of the D*(sJ)(2317)(+) and D-sJ(2460)(+) mesons in inclusive cc(-) production near root s=10.6 GeV. Physical Review D, 2006, 74 (3) doi: 10.1103/PhysRevD.74.032007
NEW
Linne, H., Yasaei, H., Marriott, A., Harvey, A., Mokbel, K., Newbold, R. and Roberts, T. (2017). Functional role of SETD2, BAP1, PARP-3 and PBRM1 candidate genes on the regulation of hTERT gene expression. Linne H, Yasaei H, Marriott A, Harvey A, Mokbel K, Newbold R, Roberts T. Functional role of SETD2, BAP1, PARP-3 and PBRM1 candidate genes on the regulation of hTERT gene expression. Oncotarget. 2017 Sep 5;8(37):61890. doi: 10.18632/oncotarget.18712
NEW
Chudasama, D., Bo, V., Hall, M., ..., Harvey, A., Karteris, E. et al. (2017). Identification of novel cancer biomarkers of prognostic value using specific gene regulatory networks (GRN): a novel role of RAD51AP1 for ovarian and lung cancers. Chudasama D, Bo V, Hall M, Anikin V, Jeyaneethi J, Gregory J, Pados G, Tucker A, Harvey A, Pink R, Karteris E. Identification of cancer biomarkers of prognostic value using specific gene regulatory networks (GRN): a novel role of RAD51AP1 for ovarian and lung cancers. Carcinogenesis. 2018 Mar 8;39(3):407-17. doi: 10.1093/carcin/bgx122
NEW
de Castro, I., Amin, H., Vinciotti, V. and Vagnarelli, P. (2017). Network of phosphatases and HDAC complexes at repressed chromatin. Cell Cycle, 16 (21), pp. 2011-2017. doi: 10.1080/15384101.2017.1371883.
NEW
Tumasyan, A., Adam, W., Asilar, E., ..., Tosi, S. et al. (2017). Measurements of the pp -> W gamma gamma and pp -> Z gamma gamma cross sections and limits on anomalous quartic gauge couplings at root s=8 TeV. JOURNAL OF HIGH ENERGY PHYSICS, 2017, (10), pp. ? - ? (36) doi: 10.1007/JHEP10(2017)072
NEW
Chudasama, D., Burnside, N., Beeson, J., Karteris, E., Rice, A. and Anikin, V. (2017). Perioperative detection of circulating tumour cells in patients with lung cancer. Oncology Letters, 2017, 14(2), pp. 1281 - 1286 doi: 10.3892/ol.2017.6366
NEW
Vagnarelli, P., Zhiteneva, A., Bonfiglio, J., Makarov, A., Colby, T., Schirmer, E., Matic, I. and Earnshaw, W. (2017). Mitotic post-translational modifications of histones promote chromatin compaction in vitro. Open Biology
NEW
Kortenkamp, A., Martin, O., Baynes, A., Silva, E., Petersen, M. and Hass, U. (2017). Supporting the organisation of a workshop on thyroid disruption – final report. Kortenkamp, A., Martin, O., Baynes, A., Silva, E., Petersen, M.A. and Hass, U. (2017) Supporting the organisation of a workshop on thyroid disruption – final report. Luxembourg : Publications Office of the European Union, 162 pp. ISBN: 978-92-79-73427-4. doi: 10.2779/921523
NEW
Holzinger, E., Verma, S., Moore, C., ..., Drenos, F. et al. (2017). Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals. BioData Mining, 2017, 10 (1) doi: 10.1186/s13040-017-0145-5
NEW
Irshad, S., Bansal, M., Guarnieri, P., ..., Lewis, A. et al. (2017). Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer. Irshad S, Bansal M, Guarnieri P, Davis H, Al Haj Zen A, Baran B, Pinna CM, Rahman H, Biswas S, Bardella C, Jeffery R. Bone morphogenetic protein and Notch signalling crosstalk in poor‐prognosis, mesenchymal‐subtype colorectal cancer. The Journal of pathology. 2017 Jun;242(2):178-92. doi: 10.1002/path.4891
NEW
Vasu, V., Turner, K., George, S., Greenall, J., Slijepcevic, P. and Griffin, D. (2017). Preterm infants have significantly longer telomeres than their term born counterparts. PLOS ONE, 12(6), e0180082, pp. 1-16, doi: 10.1371/journal.pone.0180082.
NEW
de Castro, I., Budzak, J., Di Giacinto, M., ..., Vagnarelli, P. et al. (2017). Repo-Man/PP1 regulates heterochromatin formation in interphase. de Castro, I., Budzak, J., Di Giacinto, M. et al. Repo-Man/PP1 regulates heterochromatin formation in interphase. Nat Commun 8, 14048 doi: 10.1038/ncomms14048
NEW
Federico, C., Leotta, C., Bruno, F., Longo, A., Owoka, T., Tosi, S. and Saccone, S. (2017). Nuclear repositioning of the non-translocated HLXB9 allele in the leukaemia cell line GDM-1 harbouring a t(6;7)(q23;q36). Cytogenetic and Genome Research
NEW
Wagner, R., Stubiger, G., Veigel, D., ..., Karteris, E. et al. (2017). Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells. Oncotarget, 2017
NEW
Moiseeva, V., Amelina, H., Collopy, L., Armstrong, C., Pearson, S. and Tomita, K. (2017). The telomere bouquet facilitates meiotic prophase progression and exit in fission yeast. Cell Discovery, 2017, 3 doi: 10.1038/celldisc.2017.41
NEW
Federico, C., Pappalardo, A., Ferrito, V., Tosi, S. and Saccone, S. (2017). Genomic properties of chromosomal bands are linked to evolutionary rearrangements and new centromere formation in primates. Chromosome Research, (2017)
NEW
Marouli, E., Graff, M., Medina-Gomez, C., ..., Drenos, F. et al. (2017). Rare and low-frequency coding variants alter human adult height. Nature, 2017, 542 (7640), pp. 186 - 190 doi: 10.1038/nature21039
NEW
Baker, A., Huang, W., Wang, X., ..., Lewis, A. et al. (2017). Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Baker, A., Huang, W., Wang, X.M. et al. Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Nat Commun 8, 1998 (2017). https://doi.org/10.1038/s41467-017-02295-5
NEW
Turcot, V., Lu, Y., Highland, H., ..., Drenos, F. et al. (2017). Protein-altering Variants Associated with Body Mass Index Implicate Pathways that Control Energy Intake and Expenditure in Obesity. Nature genetics, 2018, 50 (1), pp. 26 - 41 doi: 10.1038/s41588-017-0011-x
NEW
Lewis, A., Cave, P. and Hopkinson, N. (2017). Singing for Lung Health: a qualitative assessment of a British Lung Foundation programme for group leaders. BMJ Open Respiratory Research, 2017, 4 (1), pp. e000216 - e000216 doi: 10.1136/bmjresp-2017-000216
NEW
Russell, A., Cave, P., Taylor, K., Lewis, A., Hopkinson, N. and Wells, A. (2017). Rhythm and song: Breath management in Idiopathic Interstitial Pneumonias (IIP's). Pilot study. Physiotherapists, 2017 doi: 10.1183/1393003.congress-2017.pa2536
NEW
Makarov, E., Shtam TA, Kovalev RA, Pantina RA, Varfolomeeva EY and Filatov MV (2017). The rare nonsense mutation in p53 triggers alternative splicing to produce a protein capable of inducing apoptosis. Makarov EM, Shtam TA, Kovalev RA, Pantina RA, Varfolomeeva EY, et al. (2017) The rare nonsense mutation in p53 triggers alternative splicing to produce a protein capable of inducing apoptosis. PLOS ONE 12(9): e0185126. doi: 10.1371/journal.pone.0185126
NEW
Buttery, S., Lewis, A., Oey, I., Hargrave, J., Waller, D., Steiner, M., Shah, P., Kemp, S., Jordan, S. and Hopkinson, N. (2017). Patient experience of lung volume reduction procedures for emphysema: a qualitative service improvement project. ERJ Open Research, 2017, 3 (3): 00031 (7 pp.) doi: 10.1183/23120541.00031-2017
NEW
Tumasyan, A., Adam, W., Asilar, E., ..., Tosi, S. et al. (2017). Particle-flow reconstruction and global event description with the CMS detector. Journal of Instrumentation, 2017, 12 (10), pp. P10003 - P10003 doi: 10.1088/1748-0221/12/10/P10003
NEW
Maund, P., Ermler, S., Widschwendter, M. and Silva, E. (2017). Abstract P1-04-09: The missing link: Chemicals, epigenetics and breast cancer. Poster Session Abstracts, 2017 doi: 10.1158/1538-7445.sabcs16-p1-04-09
NEW
Kraja, A., Cook, J., Warren, H., ..., Drenos, F. et al. (2017). New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circulation. Cardiovascular genetics, 10 (5), (2017) doi: 10.1161/circgenetics.117.001778
NEW
van der Laan, S., Fall, T., Soumaré, A., ..., Drenos, F. et al. (2017). Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. Journal of the American College of Cardiology, 2016, 68 (9), pp. 934 - 945 doi: 10.1016/j.jacc.2016.05.092
NEW
Castro, I., Sales Gil, R., Ligammari, L., Di Giacinto, M. and Vagnarelli, P. (2017). CDK1 and PLK1 co-ordinate the disassembly and re-assembly of the Nuclear Envelope in vertebrate mitosis. Castro I. et al. (20180 'CDK1 and PLK1 coordinate the disassembly and reassembly of the nuclear envelope in vertebrate mitosis', Oncotarget, 9, pp. 7763-7773. doi: 10.18632/oncotarget.23666.
NEW
Sales Gil, R., Castro, I., Berihun, J. and Vagnarelli, P. (2017). Protein Phosphatases at the Nuclear Envelope. Sales Gil, R. et al. (2018 ) 'Protein phosphatases at the nuclear envelope', Biochemical Society Transactions, 46(1), pp. 173 - 182. doi: 10.1042/BST20170139.
NEW
Cantarella, C., Ragusa, D., Giammanco, M. and Tosi, S. (2017). Folate deficiency as predisposing factor for childhood leukaemia: A review of the literature.
NEW
Abbasi, M., Vassilopoulou, P., Stergioulas, L., Matich, M., Payne, A. and Smith, C. (2015). Use of creative tools, technologies, processes and practices in the sectors of Art, Media, and Architecture: State-of the-Art and desired future scenarios. Proceedings of the Digital Research in the Humanities and Arts conference, DRHA2014, London
NEW
Davies, J., Chen, J., Pink, R., ..., Payne, A., Karteris, E. et al. (2015). (Under review) Orexin receptors exert a neuroprotective effect in Alzheimer's disease (AD) via heterodimerization with GPR103. Scientific Reports: Nature, 2015, Under review
NEW
Davies, J., Chen, J., Pink, R., ..., Payne, A., Karteris, E. et al. (2015). Orexin receptors exert a neuroprotective effect in Alzheimer's disease (AD) via heterodimerization with GPR103. Scientific Reports, 5: 12584, (2015) doi: 10.1038/srep12584
NEW
Beaney, K., Cooper, J., Shahid, S., Ahmed, W., Qamar, R., Drenos, F., Crockard, M. and Humphries, S. (2015). Clinical utility of a coronary heart disease risk prediction gene score in UK healthy middle aged men and in the Pakistani population. Beaney, K.E., Cooper, J.A., Shahid, S.U., Ahmed, W., Qamar, R., Drenos, F., Crockard, M.A. and Humphries, S.E. (2015) PLoS ONE, 10 (7), e0130754, pp. 1-13. doi: 10.1371/journal.pone.0130754.
NEW
Iansante, V., Choy, P., Fung, S., ..., Bubici, C. et al. (2015). PARP14 promotes the warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation. Nature Communications, ARTN 7882, 6, (2015) doi: 10.1038/ncomms8882
NEW
Oldoni, F., Palmen, J., Giambartolomei, C., Howard, P., Drenos, F., Plagnol, V., Humphries, S., Talmud, P. and Smith, A. (2015). Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3. Oldoni, F., Palmen, J., Giambartolomei, C., Howard, P., Drenos, F., Plagnol, V., Humphries, S.E., Talmud, P.J. and Smith, A.J.P. (2016) 'Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3', Atherosclerosis, 246, pp. 193-201. doi: 10.1016/j.atherosclerosis.2015.12.009.
NEW
Iansante, V., Choy, P., Chokshi, S., Williams, R., Anders, R., Bubici, C. and Papa, S. (2015). Increased aerobic glycolysis is associated with poor outcome and suppression of apoptosis in human liver cirrhosis and hcc. Journal Of Hepatology,62: pp. S427 - S427 (1),(2015)
NEW
Choy, P., Sufi, J., Glaser, S., Alpini, G., Heaton, N., Williams, R., Quaglia, A., Syn, W., Bubici, C. and Papa, S. (2015). Inhibition of mapk signalling promotes cell cycle arrest and sensitises intrahepatic cholangiocarcinoma cells to chemotherapy. GUT, 64: pp. A458 - A458 (1),(2015) doi: 10.1136/gutjnl-2015-309861.1003
NEW
Iansante, V., Choy, P., Chokshi, S., Williams, R., Anders, R., Bubici, C. and Papa, S. (2015). Addressing the interplay between apoptosis and glucose metabolism in liver cirrhosis and hcc. GUT, 64: pp. A12 - A12 (1),(2015) doi: 10.1136/gutjnl-2015-309861.22
NEW
Drenos, F., Grossi, E., Buscema, M. and Humphries, S. (2015). Networks in coronary heart disease genetics as a step towards systems epidemiology. PLoS ONE, 2015, 10 (5) doi: 10.1371/journal.pone.0125876
NEW
Yan, K., Sisu, C., Cheng, C., Rozowsky, J., Meyerson, W. and Gerstein, M. (2015). Loregic: A Method to Characterize the Cooperative Logic of Regulatory Factors. PLOS COMPUTATIONAL BIOLOGY, 2015, 11 (4), pp. ? - ? (21) doi: 10.1371/journal.pcbi.1004132
NEW
Rogers-Broadway, K. and Karteris, E. (2015). Amplification efficiency and thermal stability of qPCR instrumentation: Current landscape and future perspectives. Experimental and Therapeutic Medicine, 10: pp. 1261-1264, (2015) doi: 10.3892/etm.2015.2712
NEW
Sotiriadis, G., Dodagatta-Marri, E., Kouser, L., Alhamlan, F., Kishore, U. and Karteris, E. (2015). Surfactant proteins SP-A and SP-D modulate uterine contractile events in ULTR myometrial cell line. PLoS ONE, 10(12): pp 1-18, (2015) doi: 10.1371/journal.pone.0143379
NEW
Nüesch, E., Dale, C., Palmer, T., ..., Drenos, F. et al. (2015). Adult height, coronary heart disease and stroke: A multi-locus Mendelian randomization meta-analysis. International Journal of Epidemiology, 2016, 45 (6), pp. 1927 - 1937 doi: 10.1093/ije/dyv074
NEW
Makarov, E. and Makarova, O. (2015). The 35S U5 snRNP is generated from the activated spliceosome during In vitro splicing. PLoS One, 10(5): e0128430, (2015) doi: 10.1371/journal.pone.0128430
NEW
Gérard, C., Mestdagt, M., Tskitishvili, E., ..., Silva, E. et al. (2015). Combined estrogenic and anti-estrogenic properties of estetrol on breast cancer may provide a safe therapeutic window for the treatment of menopausal symptoms. Oncotarget, 2015, 6 (19), pp. 17621 - 17636
NEW
Beaney, K., Cooper, J., Shahid, S., Ahmed, W., Qamar, R., Drenos, F., Crockard, M. and Humphries, S. (2015). Correction: Clinical utility of a coronary heart disease risk prediction gene score in UK healthy middle aged men and in the Pakistani population PLoS ONE 10 (7). doi: 10.1371/journal.pone.0130754. PLoS ONE, 10 (9), pp. 1-1. doi: 10.1371/journal.pone.0139651.
NEW
Rinaldi, G., Yan, H., Nacif-Pimenta, R., Matchimakul, P., Bridger, J., Mann, V., Smout, M., Brindley, P. and Knight, M. (2015). Cytometric analysis, genetic manipulation and antibiotic selection of the snail embryonic cell line Bge from Biomphalaria glabrata, the intermediate host of Schistosoma mansoni. International Journal of Parasitology Research, 2015, 45 (8), pp. 527 - 535
NEW
Bikkul, M., Slijepcevic, P., Anderson, R., Faragher, R., Kill, I. and Bridger, J. (2015). Genome Organisation is affected in immortalised control and Hutchinson-Gilford Progeria Cells. 20th International Chromosome Conference (ICC), Canterbury, Kent University, England, 23, (2): pp. 392 - 393, 1-4 Septemebr 2015
NEW
Pondman, K., Pednekar, L., Paudyal, B., ..., Stenbeck, G. et al. (2015). Innate immune humoral factors, C1q and factor H, with differential pattern recognition properties, alter macrophage response to carbon nanotubes.
NEW
Castro, I., Budzak, J., Di Giacinto, M. and Vagnarelli, P. (2015). Repo-Man as a chromatin organiser in the interphase nuclei. Gordon Reseach conference on Genome Architecture in Cell Fate & Disease, Hong Kong, 7-12 Jun 2015
NEW
Amelina, H., Subramaniam, S., Moiseeva, V., Armstrong, C., Pearson, S. and Tomita, K. (2015). Telomere protein Rap1 is a charge resistant scaffolding protein in chromosomal bouquet formation. BMC Biology, 2015, 13 (1), 37 (9 pp.) doi: 10.1186/s12915-015-0149-x
NEW
Fennell, A., Fernández-Álvarez, A., Tomita, K. and Cooper, J. (2015). Telomeres and centromeres have interchangeable roles in promoting meiotic spindle formation. Journal of Cell Biology, 2015, 208 (4), pp. 415 - 428 doi: 10.1083/jcb.201409058
NEW
Anjomani-Virmouni, S., Al-Mahdawi, S., Sandi, C., Yasaei, H., Slijepcevic, P. and Pook, M. (2015). Identification of telomere dysfunction in Friedreich ataxia. EMBO Conference on Telomeres, Telomerase and Disease, Brussels, Belgium, 1-4 May, pp. 1-1.
NEW
Anjomani-Virmouni, S., Al-Mahdawi, S., Sandi, C., Yasaei, H., Giunti, P., Slijepcevic, P. and Pook, M. (2015). Identification of telomere dysfunction in Friedreich ataxia. Molecular Neurodegeneration, 10, 22, pp. 1-11. doi: 10.1186/s13024-015-0019-6.
NEW
Kugathas, S., Audouze, K., Ermler, S., Orton, F., Rosivatz, E., Scholze, M. and Kortenkamp, A. (2015). Effects of common pesticides on prostaglandin D2 (PGD2) inhibition in SC5 mouse sertoli cells, evidence of binding at the cox-2 active site, and implications for endocrine disruption. Environmental Health Perspectives,124, (4): pp. 452 - 459, (2015) doi: 10.1289/ehp.1409544
NEW
Gravells, P., Ahrabi, S., Vangala, R., ..., Tomita, K. et al. (2015). Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.
NEW
Burugapalli, K., Wijesuriya, S., Mackay, R. and Balachandran, W. (2015). Insoluble electrospun membranes for analyte pre-concentration in saliva. Proc. ESA Annual Meeting on Electrostatics 2015
NEW
Owoka, T., Vetter, M., Federico, C., Saccone, S. and Tosi, S. (2015). Detection of t(7;12)(q36;p13) in paediatric leukaemia using dual colour fluorescence in situ hybridisation. Hematology and Leukemia, 3:4, (2015) doi: 10.7243/2052-434X-3-4
NEW
Tosi, S., Mostafa Kamel, Y., Owoka, T., Federico, C., Truong, T. and Saccone, S. (2015). Paediatric acute myeloid leukaemia with the t(7;12)(q36;p13) rearrangement: a review of the biological and clinical management aspects. Biomarker Research, 3(1),21, (2015) doi: 10.1186/s40364-015-0041-4
NEW
Sanghera, S., Frew, E. and Roberts, T. (2015). Adapting the CHEERS statement for reporting cost-benefit analysis. Pharmacoeconomics, 33(5): 533-534, (May 2015) doi: 10.1007/s40273-015-0265-z
NEW
Tomlinson, A., Lane, J., Julier, G., ..., Payne, A. et al. (2020). Qualitative findings from a systematic review: Visual arts engagement for adults with mental health conditions. Journal of Applied Arts & Health, 11 (3), pp. 281-297. doi: 10.1386/jaah_00042_1.
NEW
Corner, E., Zhang, X., Van Willigan, Z., ..., Harvey, A. et al. (2020). Mixed methods evaluation of the impact of the COVID-19 ICU remote-learning rehabilitation course for frontline health professionals during the COVID-19 pandemic in the UK. Corner, E.J. et al. (2022) ‘Mixed methods evaluation of the impact of the COVID-19 ICU remote-learning rehabilitation course for frontline health professionals during the COVID-19 pandemic in the UK’, Journal of the Intensive Care Society, 23 (4), pp. 485 - 491. doi: 10.1177/17511437211043043.
NEW
Jones, M., Moffatt, F., Harvey, A. and Ryan, J. (2020). Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis. Cochrane Database of Systematic Reviews, 2020 (5), Article no. CD013610, pp. 1 - 11. doi: 10.1002/14651858.CD013610.
NEW
Bomer, M., Perez Salamo, I., Florance, H., Salmon, D., Dudenhoffer, J., Finch, P., Cinar, A., Smirnoff, N., Harvey, A. and Devoto, A. (2020). Jasmonates induce Arabidopsis bioactivities selectively inhibiting the growth of breast cancer cells through CDC6 and mTOR. New Phytologist, in press, pp. 1-15. doi:10.1111/nph.17031.
NEW
Camilleri, M., Zhang, X., Norris, M., ..., Harvey, A. et al. (2020). Covid-19 ICU Remote-Learning Course (CIRLC): Rapid ICU remote training for frontline health professionals during the COVID-19 pandemic in the UK. Camilleri, M. et al. (2022) ‘Covid-19 ICU remote-learning course (CIRLC): Rapid ICU remote training for frontline health professionals during the COVID-19 pandemic in the UK’, Journal of the Intensive Care Society, 23 (2), pp. 183 - 190. doi: 10.1177/1751143720972630.
NEW
Snyder, M., Gingeras, T., Abascal, F., ..., Sisu, C. et al. (2020). Perspectives on ENCODE. Nature, 2020, 583 (7818), pp. 693 - 698. doi:10.1038/s41586-020-2449-8.
NEW
Martin, O., Ermler, S., Baynes, A. and McPhie, J. (2020). Data collection in support of the Endocrine Disruption (ED) assessment for non-target vertebrates. EFSA supporting publication, 17 (5), EN-1849, pp. 1 - 131. doi: 10.2903/sp.efsa.2020.EN-1849.
NEW
Zhang, B., Cristescu, R., Chrisey, D. and Narayan, R. (2020). Solvent-based extrusion 3D printing for the fabrication of tissue engineering scaffolds. International Journal of Bioprinting, 6 (1), pp. 28 - 42. doi: 10.18063/ijb.v6i1.211.
NEW
Lewis, A., Nolan, C., Man, W., Kon, S. and Conway, J. (2020). Prognostication in COPD using physical function measures: Let's walk before we run away with conclusions. Respiratory Medicine, 167, 105942, pp. 1 - 2. doi 10.1016/j.rmed.2020.105942. doi: 10.1016/j.rmed.2020.105942
NEW
Zahra, A., Sisu, C., Silva, E., De Aguiar Greca, S., Randeva, H., Chatha, K., Kyrou, I. and Karteris, E. (2020). Is there a link between bisphenol A (BPA), a key endocrine disruptor, and the risk for SARS-CoV-2 infection and severe COVID-19?. Zahra, A., Sisu, C., Silva, E., De Aguiar Greca, S.-C., Randeva, H. S., Chatha, K., Kyrou, I. and Karteris, E. (2020) ‘Is There a Link between Bisphenol A (BPA), a Key Endocrine Disruptor, and the Risk for SARS-CoV-2 Infection and Severe COVID-19?’, Journal of Clinical Medicine. MDPI AG, 9(10), 3296, pp. 1-15. doi: 10.3390/jcm9103296.
NEW
Scholze, M., Taxvig, C., Kortenkamp, A., ..., Ermler, S. et al. (2020). Quantitative in Vitro to in Vivo Extrapolation (QIVIVE) for Predicting Reduced Anogenital Distance Produced by Anti-Androgenic Pesticides in a Rodent Model for Male Reproductive Disorders. Environmental health perspectives, 2020, 128 (11), 117005, pp. 1-17. doi: 10.1289/EHP6774.
NEW
Goncalves, T., Zoumpoulidou, G., Alvarez-Mendoza, C., Mancusi, C., Collopy, L., Strauss, S., Mittnacht, S. and Tomita, K. (2020). Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by ATR Inhibitors. ACS Pharmacology and Translational Science, 3(6): 1253–1264. doi: 10.1021/acsptsci.0c00125.
NEW
Penn-Nicholson, A., Mbandi, S., Thompson, E., ..., Roberts, T. et al. (2020). RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response. Scientific Reports, 10 (1), 8629, pp. 1 - 21. doi: 10.1038/s41598-020-65043-8.
NEW
Surendran, P., Feofanova, E., Lahrouchi, N., ..., Drenos, F. et al. (2020). Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nature Genetics 52, pp. 1314 - 1332. doi: 10.1038/s41588-020-00713-x.
NEW
Buttery, S., Lewis, A., Kemp, S., Banya, W., Quint, J., Steiner, M. and Hopkinson, N. (2020). Lung volume reduction eligibility in patients with COPD completing pulmonary rehabilitation: results from the UK National Asthma and COPD Audit Programme. BMJ Open, 10 (11), e040942, pp. 1-5. doi: 10.1136/bmjopen-2020-040942.
NEW
Domingues, A., Kulkarni, R., Giotopoulos, G., ..., Pina, C. et al. (2020). Loss of Kat2a Enhances Transcriptional Noise and depletes Acute Myeloid Leukaemia Stem-like Cells. Elife, 9, e51754, pp. 1-29. doi: 10.7554/eLife.51754.
NEW
Zheng, J., Haberland, V., Baird, D. et al. (2020). Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases. Nature Genetics, 52 (10), pp. 1122 - 1131. doi: 10.1038/s41588-020-0682-6.
NEW
Philip, K., Lewis, A., Jeffery, E. et al. (2020). Moving singing for lung health online in response to COVID-19: experience from a randomised controlled trial. BMJ Open Respiratory Research, 2020, 7 (1), e000737, pp. 1 - 11. doi:10.1136/bmjresp-2020-000737.
NEW
O'Cathail, S., Wu, C., Lewis, A., Holmes, C., Hawkins, M. and Maughan, T. (2020). NRF2 metagene signature is a novel prognostic biomarker in colorectal cancer. Cancer Genetics, 248-249 pp. 1 - 10. doi: 10.1016/j.cancergen.2020.08.006.
NEW
Philip, K., Lewis, A., Williams, S., Buttery, S., Polkey, M., Man, W., Fancourt, D. and Hopkinson, N. (2020). Dance for people with chronic respiratory disease: A qualitative study. Philip KEJ, Lewis A, Williams S, et alDance for people with chronic respiratory disease: a qualitative studyBMJ Open 2020;10:e038719. doi: 10.1136/bmjopen-2020-038719
NEW
Martin, O., Scholze, M., Ermler, S., McPhie, J., Bopp, S., Kienzler, A., Parissis, N. and Kortenkamp, A. (2020). Ten years of research on synergisms and antagonisms in chemical mixtures: A systematic review and quantitative reappraisal of mixture studies. Martin, O. et al. (2021) 'Ten years of research on synergisms and antagonisms in chemical mixtures: A systematic review and quantitative reappraisal of mixture studies', Environment international, 146, 106206, pp. 1 - 17. doi:10.1016/j.envint.2020.106206.
NEW
Axson, E., Lewis, A., Potts, J., Pang, M., Dickinson, S., Vioix, H. and Quint, J. (2020). Inhaled therapies for chronic obstructive pulmonary disease: a systematic review and meta-analysis. BMJ Open 10 (9), e036455, pp. 1 - 11. doi: 10.1136/bmjopen-2019-036455.
NEW
Collett, G., Kai, C., William, Y., Mary, G. and Anderson, R. (2020). The psychological consequences of (perceived) ionizing radiation exposure: a review on its role in radiation-induced cognitive dysfunction. International Journal of Radiation Biology, 96 (9), pp. 1104 - 1118, doi: 10.1080/09553002.2020.1793017.
NEW
Liu, Y., Elsworth, B., Erola, P., Haberland, V., Hemani, G., Lyon, M., Zheng, J., Lloyd, O., Vabistsevits, M. and Gaunt, T. (2020). EpiGraphDB: A database and data mining platform for health data science. Liu, Y. et al. (2021) 'EpiGraphDB: A database and data mining platform for health data science', Bioinformatics, 37 (9), pp. 1304 - 1311. doi: 10.1093/bioinformatics/btaa961.
NEW
de Aguiar Greca, S., Kyrou, I., Pink, R., Randeva, H., Grammatopoulos, D., Silva, E. and Karteris, E. (2020). Involvement of the Endocrine-Disrupting Chemical Bisphenol A (BPA) in Human Placentation. de Aguiar Greca, S.-C.; Kyrou, I.; Pink, R.; Randeva, H.; Grammatopoulos, D.; Silva, E.; Karteris, E. Involvement of the Endocrine-Disrupting Chemical Bisphenol A (BPA) in Human Placentation. J. Clin. Med. 2020, 9, 405. doi: 10.3390/jcm9020405
NEW
The ENCODE Project Consortium, Moore, J., Weng, Z. and Sisu, C. (2020). Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature,, 583, pp. 699 - 710. doi: 10.1038/s41586-020-2493-4.
NEW
Li, J., Dong, W., Zhang, B. and Zhou, X. (2020). Effects of creep recovery on the fracture properties of concrete. Theoretical and Applied Fracture Mechanics, 109, 102694, pp. 1 - 9. doi: 10.1016/j.tafmec.2020.102694.
NEW
Goncalves, T., Zoumpoulidou, G., Alvarez-Mendoza, C., Mancusi, C., Collopy, L., Strauss, S., Mittnacht, S. and Tomita, K. (2020). Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by ATR Inhibitors. ACS Pharmacology & Translational Science, in press (12 pp.). doi: 10.1021/acsptsci.0c00125.
NEW
Davies, J., Randeva, H., Chatha, K., Hall, M., Spandidos, D., Karteris, E. and Kyrou, I. (2020). Neuropilin‑1 as a new potential SARS‑CoV‑2 infection mediator implicated in the neurologic features and central nervous system involvement of COVID‑19. Molecular Medicine Reports, 22 (5), pp. 4221 - 4226. doi: 10.3892/mmr.2020.11510.
NEW
Zhang, B., Chung, S., Barker, S., Craig, D., Narayan, R. and Huang, J. (2020). Direct ink writing of polycaprolactone / polyethylene oxide based 3D constructs. Zhang, B. et al. (2021) 'Direct ink writing of polycaprolactone / polyethylene oxide based 3D constructs', Progress in Natural Science: Materials International, 31 (2), pp. 180 - 191. doi: 10.1016/j.pnsc.2020.10.001.
NEW
Slijepcevic, P. (2020). Natural Intelligence and Anthropic Reasoning. . Biosemiotics, 13, pp. 285 - 307. doi: 10.1007/s12304-020-09388-7.
NEW
Chong, W., Wang, W., Lo, C., ..., Tanos, B. et al. (2020). Super-resolution microscopy reveals coupling between mammalian centriole subdistal appendages and distal appendages. eLife, 9, e53580, pp. 1-xx. doi: 10.7554/eLife.53580.
NEW
Arede, L. and Pina, C. (2020). Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and development. Arede, L. and Pina, C. (2021) 'Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and development', Experimental hematology, 93, pp. 25-37. doi: 10.1016/j.exphem.2020.10.003.
NEW
Saravi, S., Katsuta, E., Jeyaneethi, J., Amin, H., Kaspar, M., Takabe, K., Pados, G., Drenos, F. and Hall, M. (2020). H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival. Saravi, S., Katsuta, E., Jeyaneethi, J., Amin, H. A., Kaspar, M., Takabe, K., Pados, G., Drenos, F., Hall, M. and Karteris, E. (2020) ‘H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival’, Journal of Clinical Medicine. MDPI AG, 9(9), 2844, pp. 1-14. doi: 10.3390/jcm9092844.
NEW
Katopodis, P., Dong, Q., Halai, H., Fratila, C., Polychronis, A., Anikin, V., Sisu, C. and Karteris, E. (2020). In silico and in vitro analysis of lncRNA XIST reveals a panel of possible lung cancer regulators and a five-gene diagnostic signature. Katopodis, P., Dong, Q., Halai, H., Fratila, C. I., Polychronis, A., Anikin, V., Sisu, C. and Karteris, E. (2020) ‘In Silico and In Vitro Analysis of lncRNA XIST Reveals a Panel of Possible Lung Cancer Regulators and a Five-Gene Diagnostic Signature’, Cancers, 12 (12), 3499 , pp. 1 - 16. doi: 10.3390/cancers12123499.
NEW
Sisu, C., Muir, P., Frankish, A. et al. (2020). Transcriptional activity and strain-specific history of mouse pseudogenes. Nature Communications, 11, 3695, pp. 1-14. doi: 10.1038/s41467-020-17157-w.
NEW
Klonos, E., Katopodis, P., Karteris, E., Papanikolaou, E., Tarlatzis, B. and Pados, G. (2020). Endometrial changes in estrogen and progesterone receptor expression during implantation in an oocyte donation program. Klonos, E., Katopodis, P., Karteris, E., Papanikolaou, E., Tarlatzis, B., & Pados, G. (2020). Endometrial changes in estrogen and progesterone receptor expression during implantation in an oocyte donation program. Experimental and Therapeutic Medicine, 20, 178. doi: 10.3892/etm.2020.9308
NEW
Carter, T., Jeyaneethi, J., Kumar, J., Karteris, E., Glynne-Jones, R. and Hall, M. (2020). Identification of Cancer-Associated Circulating Cells in Anal Cancer Patients. Carter, T.J.; Jeyaneethi, J.; Kumar, J.; Karteris, E.; Glynne-Jones, R.; Hall, M. Identification of Cancer-Associated Circulating Cells in Anal Cancer Patients. Cancers 2020, 12, 2229. doi: 10.3390/cancers12082229
NEW
Murugaiah, V., Agostinis, C., Varghese, P., ..., Roberts, T. et al. (2020). Hyaluronic Acid Present in the Tumor Microenvironment Can Negate the Pro-apototic Effect of a Recombinant Fragment of Human Surfactant Protein D on Breast Cancer Cells. Frontiers in Immunology, 11, 1171, pp. 1-17. doi: 10.3389/fimmu.2020.01171.
NEW
Katopodis, P., Anikin, V., Randeva, H., Spandidos, D., Chatha, K., Kyrou, I. and Karteris, E. (2020). Pan‑cancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARS‑CoV‑2 infection leading to COVID-19. International Journal of Oncology, 2020, 57(2): 533 - 539 doi: 10.3892/ijo.2020.5071
NEW
Philip, K., Lewis, A., Buttery, S., McCabe, C., Manivannan, B., Fancourt, D., Orton, C., Polkey, M. and Hopkinson, N. (2020). The physiological demands of Singing for Lung Health compared to treadmill walking. Philip, K.E.J., Lewis, A., Buttery, S.C., McCabe, C., Manivannan, B., Fancourt, D., Orton, C., Polkey, M.I. and Hopkinson, N.S. 'The physiological demands of Singing for Lung Health compared to treadmill walking', medRxiv, in press, pp. 1-17. doi: 10.1101/2020.12.08.20245746.
NEW
Barr, J., Chudasama, D., Rice, A., Karteris, E. and Anikin, V. (2020). Lack of association between screencell-detected circulating tumour cells and long-term survival of patients undergoing surgery for non-small cell lung cancer: A pilot clinical study. Barr, J., Chudasama, D., Rice, A., Karteris, E., & Anikin, V. (2020). Lack of association between Screencell-detected circulating tumour cells and long‑term survival of patients undergoing surgery for non‑small cell lung cancer: A pilot clinical study. Molecular and Clinical Oncology, 12, 191-195. https://doi.org/10.3892/mco.2020.1981
NEW
Kerslake, R., Hall, M., Randeva, H., Spandidos, D., Chatha, K., Kyrou, I. and Karteris, E. (2020). Co‑expression of peripheral olfactory receptors with SARS‑CoV‑2 infection mediators: Potential implications beyond loss of smell as a COVID‑19 symptom. International Journal of Molecular Medicine doi: 10.3892/ijmm.2020.4646
NEW
Kyrou, I., Karteris, E., Robbins, T., Chatha, K., Drenos, F. and Randeva, H. (2020). Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic. Kyrou, I., Karteris, E., Robbins, T. et al. Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic. BMC Med 18, 220 (2020). https://doi.org/10.1186/s12916-020-01697-5
NEW
Syeda, A., Dimude, J., Skovgaard, O. and Rudolph, C. (2020). Too much of a good thing: how ectopic DNA replication affects bacterial replication dynamics. Frontiers in Microbiology, 11, 534, pp. 1-21. doi: 10.3389/fmicb.2020.00534.
NEW
Pavitt, M., Tanner, R., Lewis, A. et al. (2020). Oral nitrate supplementation to enhance pulmonary rehabilitation in COPD: ON-EPIC a multi-centre, double-blind, placebo-controlled, randomised parallel group study. Thorax
NEW
Lewis, A., Russell, H., Kedzierska, K. et al. (2020). The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability. Clinical Epigenetics 12, 102, pp. 1-9. https://doi.org/10.1186/s13148-020-00889-3
NEW
Balogh, E., Chandler, J., Varga, M., ..., Tomita, K. et al. (2020). Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. Eszter Balogh, Jennifer C. Chandler, Máté Varga, Mona Tahoun, Dóra K. Menyhárd, Gusztáv Schay, Tomas Goncalves, Renáta Hamar, Regina Légrádi, Ákos Szekeres, Olivier Gribouval, Robert Kleta, Horia Stanescu, Detlef Bockenhauer, Andrea Kerti, Hywel Williams, Veronica Kinsler, Wei-Li Di, David Curtis, Maria Kolatsi-Joannou, Hafsa Hammid, Anna Szőcs, Kristóf Perczel, Erika Maka, Gergely Toldi, Florentina Sava, Christelle Arrondel, Magdolna Kardos, Attila Fintha, Ahmed Hossain, Felipe D’Arco, Mario Kaliakatsos, Jutta Koeglmeier, William Mifsud, Mariya Moosajee, Ana Faro, Eszter Jávorszky, Gábor Rudas, Marwa H. Saied, Salah Marzouk, Kata Kelen, Judit Götze, George Reusz, Tivadar Tulassay, François Dragon, Géraldine Mollet, Susanne Motameny, Holger Thiele, Guillaume Dorval, Peter Nürnberg, András Perczel, Attila J. Szabó, David A. Long, Kazunori Tomita, Corinne Antignac, Aoife M. Waters, Kálmán Tory; Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis; Proceedings of the National Academy of Sciences Jun 2020, 202002328; doi: 10.1073/pnas.2002328117
NEW
Legler, J., Zalko, D., Jourdan, F., ..., Ermler, S. et al. (2020). The goliath project: Towards an internationally harmonised approach for testing metabolism disrupting compounds. Legler, J., Zalko, D., Jourdan, F., Jacobs, M., Fromenty, B., Balaguer, P., Bourguet, W., Munic Kos, V., Nadal, A., Beausoleil, C., Cristobal, S., Remy, S., Ermler, S., Margiotta-Casaluci, L., Griffin, J. L., Blumberg, B., Chesné, C., Hoffmann, S., Andersson, P. L. and Kamstra, J. H. (2020) ‘The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds’, International Journal of Molecular Sciences, 21(10), 3480, pp. 1-18. doi: 10.3390/ijms21103480.
NEW
Sales Gil, R. and Vagnarelli, P. (2020). How HP1 post-translational modifications regulate heterochromatin formation and maintenance. Cells, 9 (6), 1460, pp. 1-13. doi: 10.3390/cells9061460.
NEW
Ghorbani, M., Pousset, F., Tucker, A., Swift, S., Giunti, P., Parkinson, M., Gilbert, D., Liu, X. and Payne, A. (2019). Analysis of Friedreich's ataxia patient clinical data reveals importance of accurate GAA repeat determination in disease prognosis and gender differences in cardiac measures. Ghorbani, Mohammadmersad; Pousset, Françoise; Tucker, Allan; Swift, Stephen; Giunti, Paola; Parkinson, Michael; Gilbert, David; Liu, XiaoHui; Payne, Annette; Analysis of Friedreich's ataxia patient clinical data reveals importance of accurate GAA repeat determination in disease prognosis and gender differences in cardiac measures, Informatics in Medicine Unlocked, 17, 2019, 100266 doi: 10.1016/j.imu.2019.100266
NEW
Gruffydd-Jones, K., Keeley, D., Knowles, V., ..., Harvey, A. et al. (2019). Primary care implications of the British Thoracic Society Guidelines for bronchiectasis in adults 2019. npj Primary Care Respiratory Medicine, 2019, pp. 1 - 7 doi: 10.1038/s41533-019-0136-8
NEW
Mansell, S., Harvey, A. and Thomas, A. (2019). An exploratory study considering the potential impacts of high-fidelity simulation training on self-evaluated confidence of non-respiratory physiotherapists providing an on-call respiratory physiotherapy service - a mixed methods study. Mansell, S.K., Harvey, A. and Thomas, A.J. (2020) 'An exploratory study considering the potential impacts of high-fidelity simulation training on self-evaluated confidence of non-respiratory physiotherapists providing an on-call respiratory physiotherapy service - a mixed methods study', BMJ Simulation and Technology Enhanced Learning, 6 (4), pp. 199 - 205 (7). doi: 10.1136/bmjstel-2019-000444.
NEW
Vidotto, L., Carvalho, C., Harvey, A. and Jones, M. (2019). Dysfunctional breathing: what do we know?. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2019, 45 (1), pp. 1 - 9 doi: 10.1590/1806-3713/e20170347
NEW
Zhang, B., Huang, Z., Rahi, B., Wang, Q. and Li, M. (2019). Online semi-supervised multi-person tracking with gaussian process regression. (from the Proceedings of the 2018 International Joint Conference on Metallurgical and Materials Engineering (JCMME 2018), Wellington, New Zealand, 10-12 December 2018) MATEC Web of Conferences, 277, 01003, pp. 1-8. doi: 10.1051/matecconf/201927701003.
NEW
Lightbody, G., Haberland, V., Browne, F., Taggart, L., Zheng, H., Parkes, E. and Blayney, J. (2019). Review of applications of high-throughput sequencing in personalized medicine: Barriers and facilitators of future progress in research and clinical application. Briefings in Bioinformatics, 20 (5), pp. 1795 - 1811. doi: 10.1093/bib/bby051.
NEW
Ingold, N., Amin, H. and Drenos, F. (2019). Alcohol causes an increased risk of head and neck but not breast cancer in individuals from the UK Biobank study: A Mendelian randomisation analysis. medRxiv, 19002832, pp. 1 - 20. doi: 10.1101/19002832.
NEW
Justice, A., Karaderi, T., Highland, H., ..., Drenos, F. et al. (2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics, 51, pp. 452 - 469. doi: 10.1038/s41588-018-0334-2.
NEW
Deelen, J., Kettunen, J., Fischer, K., ..., Drenos, F. et al. (2019). A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals. Nature Communications, 2019, 10 (1), 3346, pp. 1 - 6. doi: 10.1038/s41467-019-11311-9.
NEW
Thomas, R., Trapani, D., Goodyer-Sait, L., ..., Lewis, A. et al. (2019). The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression. Scientific Reports, 2019, 9 (1), Article number: 13463 (10) doi: 10.1038/s41598-019-49952-x
NEW
Lewis, A., Dullaghan, D., Townes, H., Green, A., Potts, J. and Quint, J. (2019). An observational cohort study of exercise and education for people with chronic obstructive pulmonary disease not meeting criteria for formal pulmonary rehabilitation programmes. Chronic Respiratory Disease, 2019, 16: (12) doi: 10.1177/1479973119838283
NEW
Tachmazidou, I., Hatzikotoulas, K., Southam, L., ..., Haberland, V. et al. (2019). Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.
NEW
Clements, C., Bikkul, M., Ofosu, W., Eskiw, C., Tree, D., Makarov, E., Kill, I. and Bridger, J. (2019). Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways. Biogerontology 20 (3), pp. 337 - 358. doi: 10.1007/s10522-019-09807-4.
NEW
Karteris, E., Nieddu, V., Piredda, R., Bexel, D., Barton, J., Anderson, J., Sebire, N., Kolluri, K., Janes, S. and Sala, A. (2019). Engineered human mesenchymal stem cells for neuroblastoma therapeutics. Oncology Reports
NEW
Bubici, C., Lepore, A. and Papa, S. (2019). ASKing No More: The Emerging Role of Dual-Specific Phosphatase 12 in the Regulation of Hepatic Lipid Metabolism. Hepatology, 2019, 70 (4), pp. 1091 - 1094 doi: 10.1002/hep.30851
NEW
Bubici, C. and Papa, S. (2019). Editorial: The Warburg effect regulation under siege: The intertwined pathways in health and disease. Frontiers in Cell and Developmental Biology, 2019, 7 (May) doi: 10.3389/fcell.2019.00080
NEW
Lewis, A. and Hopkinson, N. (2019). Tai Chi Movements for Wellbeing – evaluation of a British Lung Foundation pilot. Perspectives in Public Health, 2019, 20 (11), pp. 1 - 9 doi: 10.1177/1757913919872515
NEW
Meagher, N., Wang, L., Rambau, P., ..., Zhang, B. et al. (2019). A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases. Modern Pathology, 32 (12), pp. 1834 - 1846. doi: 10.1038/s41379-019-0302-0.
NEW
Chudasama, D., Katopodis, P., Stone, N., ..., Sisu, C., Karteris, E. et al. (2019). Liquid biopsies in lung cancer: Four emerging technologies and potential clinical applications. Cancers doi: 10.3390/cancers11030331
NEW
Al-Qahtani, A., Murugaiah, V., Bashir, H., Pathan, A., Abozaid, S., Makarov, E., Nal, B., Kishore, U. and Al-Ahdal, M. (2019). Full-length human Surfactant Protein A inhibits Influenza A Virus infection of A549 lung epithelial cells: a recombinant form containing neck and lectin domains promotes infectivity. Immunobiology
NEW
Kumar, J., Chudasama, D., Charlotee, R., Kubista, M., Sjoback, R., Chatterjee, J., Anikin, V., Karteris, E. and Hall, M. (2019). Detection of Abundant Non-Haematopoietic Circulating Cancer-Related Cells in Patients with Advanced Epithelial Ovarian Cancer. Cells, 2019
NEW
Karteris, E., Kumar, J., Murugaiah, V. et al. (2019). Surfactant Protein D as a Potential Biomarker and Therapeutic Target in Ovarian Cancer. Frontiers in Oncology, 9, 542, pp. 1-14. doi: 10.3389/fonc.2019.00542
NEW
Federico, C., Owoka, T., Ragusa, D., ..., Sisu, C. et al. (2019). Deletions of Chromosome 7q Affect Nuclear Organization and HLXB9Gene Expression in Hematological Disorders. Federico, C., Owoka, T., Ragusa, D., Sturiale, V., Caponnetto, D., Leotta, C. G., Bruno, F., Foster, H. A., Rigamonti, S., Giudici, G., Cazzaniga, G., Bridger, J. M., Sisu, C., Saccone, S. and Tosi, S. (2019) ‘Deletions of Chromosome 7q Affect Nuclear Organization and HLXB9Gene Expression in Hematological Disorders’, Cancers, 11(4), 585, pp. 1-19. doi: 10.3390/cancers11040585.
NEW
Apps, M., Pavitt, M., Lewis, A., Orton, C., Sadaka, A., Garner, J., Hind, M., Hopkinson, N., Polkey, M. and Hull, J. (2019). Increasing CPAP (continuous positive airway pressure) leads to increasing transpulmonary pressure with increased activity of the abdominal wall muscles to aid expiration. European Respiratory Society International Congress. Madrid, Spain, 28 September - 2 October 2019.
NEW
Katopodis, P., Chudasama, D., Wander, G., Sales, L., Kumar, J., Pandhal, M., Anikin, V., Chatterjee, J., Hall, M. and Karteris, E. (2019). Kinase inhibitors and ovarian cancer. Cancers, 2019, 11 (9), 1357 (17) doi: 10.3390/cancers11091357
NEW
Rudolph, C., Corocher, T., Grainge, I. and Duggin, I. (2019). Termination of DNA Replication in Prokaryotes. eLS, 2019 doi: 10.1002/9780470015902.a0001056.pub3
NEW
Lewis, A., Bruton, A. and Donovan-Hall, M. (2019). Uncertainty prior to pulmonary rehabilitation in primary care. Chronic Respiratory Disease, 2014, 11 (3), pp. 173 - 180 doi: 10.1177/1479972314539981
NEW
Lewis, A. (2019). CRISPR-Cas9 causes chromosomal instability and re-arrangements in cancer cell lines, detectable by cytogenetic methods. The CRISPR-Journal
NEW
Philip, K., Lewis, A. and Hopkinson, N. (2019). Music and dance in chronic lung disease. Breathe, 2019, 15 (2), pp. 116 - 120 doi: 10.1183/20734735.0007-2019
NEW
Lewis, A., Axson, E., Potts, J., Tarnowska, R., Vioix, H. and Quint, J. (2019). Protocol for a systematic literature review and network meta-analysis of the clinical benefit of inhaled maintenance therapies in chronic obstructive pulmonary disease. BMJ Open, 9 (2), e025048, pp. 1 - 7. doi: 10.1136/bmjopen-2018-025048.
NEW
Ragusa, D., Makarov, E., Britten, O., Moralli, D., Green, C. and Tosi, M. (2019). The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): revised characterisation of cytogenetic features. Cancer Reports doi: 10.1002/cnr2.1207
NEW
Slijepcevic, P. (2019). Principles of information processing and natural learning in biological systems. Journal for General Philosophy of Science, 2019, pp. 1 - 19 (19) doi: 10.1007/s10838-019-09471-9
NEW
Britten, O., Ragusa, D., Tosi, S. and Kamel, Y. (2019). MLL-rearranged acute leukemia with t(4;11)(q21;q23) - current treatment options. Is there a role for CAR-T cell therapy?. Britten, O., Ragusa, D., Tosi, S. and Kamel, Y.M. (2019) ‘MLL-Rearranged Acute Leukemia with t(4;11)(q21;q23)—Current Treatment Options. Is There a Role for CAR-T Cell Therapy?’, Cells, 8 (11), 1341, p. 1-22. doi: 10.3390/cells8111341.
NEW
Amin, H., Drenos, F. and Blakemore, A. (2019). Variation at the Klotho gene locus does not affect cognitive function in up to 335,074 British Caucasians in the UK Biobank. bioRxiv, 838409, pp. 1 - 24. doi: 10.1101/838409.
NEW
Barravecchia, I., De Cesari, C., Pyankova, O., Scebba, F., Pè, M., Forcato, M., Bicciato, S., Foster, H., Bridger, J. and Angeloni, D. (2019). A comprehensive molecular and morphological study of the effects of space flight on human capillary endothelial cells: sample quality assessment and preliminary results. Frontiers in Physiology. Conference Abstract: 39th ISGP Meeting & ESA Life Sciences Meeting. abstract 50, pp. [1-2]. doi: 10.3389/conf.fphys.2018.26.00050.
NEW
Lucendo-Villarin, B., Rashidi, H., Alhaque, S., Fischer, L., Meseguer-Ripolles, J., Wang, Y., O'Farrelly, C., Themis, M. and Hay, D. (2019). Serum free production of three-dimensional human hepatospheres from pluripotent stem cells. Journal of visualized experiments : JoVE, 149, e59965, pp. 1-8. doi: 10.3791/59965.
NEW
Huguet, F., Flynn, S. and Vagnarelli, P. (2019). The Role of Phosphatases in Nuclear Envelope Disassembly and Reassembly and Their Relevance to Pathologies. Cells, 8 (7), pp. 687 - 687 doi: 10.3390/cells8070687
NEW
Box, C., Pennington, C., Hare, S., Porter, S., Edwards, D., Eccles, S., Crompton, M. and Harvey, A. (2023). Brk/PTK6 and Involucrin Expression May Predict Breast Cancer Cell Responses to Vitamin D. International Journal of Molecular Sciences, 2023, 24, 10757, pp. 1 - 14. doi: 10.3390/ijms241310757.
NEW
McAuley, H., Evans, R., Brightling, C., ..., Harvey, A. et al. (2023). Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study. eClinicalMedicine, 57, 101896, pp. 1 - x. doi: 10.1016/j.eclinm.2023.101896.
NEW
Jerin, S., Harvey, A. and Lewis, A. (2023). Therapeutic Potential of Protein Tyrosine Kinase 6 in Colorectal Cancer. Cancers, 15 (14), 3703, pp. 1 - 17. doi: 10.3390/cancers15143703.
NEW
Jones, M., Moffatt, F., Harvey, A. and Ryan, J. (2023). Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis. Cochrane Database of Systematic Reviews, 2023 (7), Art. No.: CD013610, pp. 1 - 53. doi: 10.1002/14651858.CD013610.pub2.
NEW
Pairo-Castineira, E., Rawlik, K., Bretherick, A., ..., Harvey, A., Lewis, A. et al. (2023). GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19. Nature, 617 (7962), pp. 764 - 768. doi: 10.1038/s41586-023-06034-3.
NEW
Drenos, F., Emmett, P., Blakemore, A., Nordström, T., Hurtig, T., Jarvelin, M. and Dovey, T. (2023). Associations of adolescents’ diet and meal patterns with school performance in the Northern Finland Birth Cohort 1986: A Mendelian randomisation study. Appetite, 190, 107036, pp. 1 - 10. doi: 10.1016/j.appet.2023.107036.
NEW
Buttery, S., Banya, W., Boyd, E., ..., Lewis, A. et al. (2023). Lung volume reduction surgery versus endobronchial valves: a randomised controlled trial. European Respiratory Journal, 61 (4), 2202063, pp. 1 - 14. doi: 10.1183/13993003.02063-2022.
NEW
Lepore, A., Kaci, F., Bubici, C. and Papa, S. (2023). An Integrated Methodology to Quantify the Glycolytic Stress in Plasma Cell Myeloma in Response to Cytotoxic Drugs. in Papa, S. and Bubici, C. (eds.) Methods in Molecular Biology, 2675, pp. 285 - 296. doi: 10.1007/978-1-0716-3247-5_21.
NEW
Grillo, L., Russell, A., Shannon, H., Cullinan, P. and Lewis, A. (2023). The Physiotherapy Assessment of Breathing Pattern Disorder: A Qualitative evaluation. BMJ Open Respiratory Research, 10 (1), e001395, pp.1-9. doi: 10.1136/bmjresp-2022-001395.
NEW
Schreglmann, S., Goncalves, T., Grant‐Peters, M., Kia, D., Soreq, L., Ryten, M., Wood, N., Bhatia, K. and Tomita, K. (2023). Age‐related telomere attrition in the human putamen. Aging Cell, 0 (ahead-of-print), e13861, pp. 1 - 14. doi: 10.1111/acel.13861.
NEW
Alizzi, Z., Roxburgh, P., Cartwright, D., ..., Karteris, E. et al. (2023). Description of a Retrospective Cohort of Epithelial Ovarian Cancer Patients with Brain Metastases: Evaluation of the Role of PARP Inhibitors in this Setting. Journal of Clinical Medicine, 12 (7), 2497, pp. 1 - 13. doi: 10.3390/jcm12072497.
NEW
Ragusa, D., Dijkhuis, L., Pina, C. and Tosi, S. (2023). Mechanisms associated with t(7;12) acute myeloid leukaemia: from genetics to potential treatment targets. Bioscience Reports, 43 (1), BSR20220489, pp. 1 - 17. doi: 10.1042/bsr20220489.
NEW
Mustafov, D., Karteris, E. and Braoudaki, M. (2023). Deciphering the Role of microRNA Mediated Regulation of Coronin 1C in Glioblastoma Development and Metastasis. Non-coding RNA, 9 (1), pp. 1 - 18. doi: 10.3390/ncrna901000.4.
NEW
Ragusa, D. and Vagnarelli, P. (2023). Contribution of histone variants to aneuploidy: a cancer perspective. Ragusa, D. and Vagnarelli, P. (2023) ‘Contribution of histone variants to aneuploidy: a cancer perspective’, Frontiers in Genetics, 14, 1290903, pp. 1 - 17. doi: 10.3389/fgene.2023.1290903.
NEW
Eastwood, M., Marc, S., Gao, X., ..., Karteris, E. et al. (2023). Malignant Mesothelioma subtyping via sampling driven multiple instance prediction on tissue image and cell morphology data. Artificial Intelligence in Medicine, 143, 102628, pp. 1 - 7. doi: 10.1016/j.artmed.2023.102628.
NEW
Zhang, B., Belton, P., Teoh, X., Gleadall, A., Bibb, R. and Qi, S. (2023). An investigation into the effects of ink formulations of semi-solid syringe extrusion 3D printing on the performance of the printed solid dosage forms. Zhang, B. et al. (2023) ‘An investigation into the effects of ink formulations of semi-solid syringe extrusion 3D printing on the performance of the printed solid dosage forms', Journal of Materials Chemistry B, 12 (1)., pp. 131 - 144. doi: 10.1039/d3tb01868g.
NEW
Freke, G., Martins, T., Davies, R., ..., Hernandez, V. et al. (2023). De-Suppression of Mesenchymal Cell Identities and Variable Phenotypic Outcomes Associated with Knockout of Bbs1. Cells, 12 (22), 2662, pp. 1 - 21. doi: 10.3390/cells12222662.
NEW
James, E., Sagi-Kiss, V., Bennett, M., Mycielska, M., Karen-Ng, L., Roberts, T., Matta, S., Dokal, I., Bundy, J. and Parkinson, E. (2023). Dyskeratosis Congenita links telomere attrition to age-related systemic energetics. The Journals of Gerontology: Series A, 78 (5), pp. 780 - 789. doi: 10.1093/gerona/glad018.
NEW
Mokbel, K., Kodresko, A., Ghazal, H., Mokbel, R., Trembley, J. and Jouhara, H. (2023). The Evolving Role of Cryosurgery in Breast Cancer Management: A Comprehensive Review. Cancers, 15 (17), 4272, pp. 1 - 13. doi: 10.3390/cancers15174272.
NEW
Zeka, K., Taylor, A., Samarista, R., ..., Pina, C. et al. (2023). MAT2A inhibition in AML unveils therapeutic potential of combining DNA demethylating agents with UPR targeting. bioRxiv, [preprint], 2023.06.05.543499, pp. 1 - 20. doi: 10.1101/2023.06.05.543499.
NEW
Ahmed, A., Amin, H., Drenos, F., Sattar, N. and Yaghootkar, H. (2023). Genetic Evidence Strongly Supports Managing Weight and Blood Pressure in Addition to Glycemic Control in Preventing Vascular Complications in People With Type 2 Diabetes. Diabetes Care, 2023, 46 (10), pp. 1783 - 1791. doi: 10.2337/dc23-0855.
NEW
Alizzi, Z., Gogbashian, A., Karteris, E. and Hall, M. (2023). Development of a dual energy CT based model to assess response to treatment in patients with high grade serous ovarian cancer: a pilot cohort study. Alizzi, Z. et al. (2023) ‘Development of a dual energy CT based model to assess response to treatment in patients with high grade serous ovarian cancer: a pilot cohort study’, Cancer Imaging, 23 (62), pp.1 - 11. doi: 10.1186/s40644-023-00579-2.
NEW
Zhang, B., Lu, Y., Yong, R., Zou, G., Yang, R., Pan, J. and Li, M. (2023). A spatial correlation prediction model of urban PM2.5 concentration based on deconvolution and LSTM. Neurocomputing, 0 (accepted, in press), pp. [1] - [15].
NEW
Musvosvi, M., Huang, H., Wang, C., ..., Roberts, T. et al. (2023). T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection. Nature Medicine, 29 (1), pp. 258 - 269. doi: 10.1038/s41591-022-02110-9.
NEW
Steinmann, J., Lewis, A., Ellmers, T., Jones, M., MacBean, V. and Kal, E. (2023). Validating the Breathing Vigilance Questionnaire for use in Dysfunctional Breathing. European Respiratory Journal, 61 (6), 2300031 (23 pp.). doi: 10.1183/13993003.00031-2023.
NEW
Dijkhuis, L., Johns, A., Ragusa, D., van den Brink, S. and Pina, C. (2023). Haematopoietic development and HSC formation in vitro: promise and limitations of gastruloid models. Dijkhuis, L. et al. (2024) ‘M-FISH evaluation of chromosome aberrations to examine for historical exposure to ionising radiation due to participation at British nuclear test sites’ in Journal of Radiological Protection, 7 (4), pp. 439 - 454. doi: 10.1042/ETLS20230091.
NEW
Brown, M., Leon, A., Kedzierska, K., ..., Lewis, A. et al. (2023). Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis. EMBO Molecular Medicine, 15 (10), e17094, pp. 1 - 18. doi: 10.15252/emmm.202217094.
NEW
Kaci, F., Lepore, A., Papa, S. and Bubici, C. (2023). Screening Kinase-Dependent Phosphorylation of Key Metabolic Reprogramming Regulators.
NEW
Zhang, B. (2023). Computational fluid dynamics analysis of the fluid environment of 3D printed tissue scaffolds within a perfusion bioreactor: the effect of pore shape. Procedia Structural Integrity, 49, pp. 3 - 9. doi: 10.1016/j.prostr.2023.10.002.
NEW
Stamatiou, K., Chmielewska, A., Ohta, S., Earnshaw, W. and Vagnarelli, P. (2023). CCDC86 is a novel Ki-67-interacting protein important for cell division. Journal of Cell Science, 136 (2), pp. 1 - 13. doi: 10.1242/jcs.260391.
NEW
Eastwood, M., Sailem, H., Tudor, S., ..., Karteris, E. et al. (2023). MesoGraph: Automatic Profiling of Malignant Mesothelioma Subtypes from Histological Images. arXiv:2302.12653v1 [cs.CV], pp. 1 - 20. doi: 10.48550/arXiv.2302.12653.
NEW
Kerslake, R., Belay, B., Panfilov, S., Hall, M., Kyrou, I., Randeva, H., Hyttinen, J., Karteris, E. and Sisu, C. (2023). Transcriptional Landscape of 3D vs. 2D Ovarian Cancer Cell Models. Cancers, 15 (13), 3350, pp. 1 - 21. doi: 10.3390/cancers15133350.
NEW
Cullen, S., Mackay, R., Mohagheghi, A. and Du, X. (2023). 3D Motion Analysis for the Assessment of Dynamic Coupling in Transtibial Prosthetics: A Proof of Concept. IEEE Open Journal of Engineering in Medicine and Biology, 4, pp. 141 - 147. doi: 10.1109/ojemb.2023.3296978.
NEW
Ramzi, N., Auvinen, J., Veijola, J., ..., Drenos, F. et al. (2023). Depression mediates the relationship between alexithymia and obesity in the Northern Finland Birth Cohort 1966 (NFBC1966). Journal of Affective Disorders, 331, pp. 1 - 7. doi: 10.1016/j.jad.2023.03.026.
NEW
Alizzi, Z., Saravi, S., Khalique, S., Mcdonald, T., Karteris, E. and Hall, M. (2023). Identification of RAD51 foci in cancer-associated circulating cells of patients with high-grade serous ovarian cancer: Association with treatment outcomes. International Journal of Gynecological Cancer, 33 (9), pp. 1427 - 1433. doi: 10.1136/ijgc-2023-004483.
NEW
D’Avino, P., Vagnarelli, P. and Wilde, A. (2023). Editorial: Mechanics and regulation of mitotic exit and cytokinesis. Frontiers in Cell and Developmental Biology, 11, 1191987, pp. 1 - 3. doi: 10.3389/fcell.2023.1191987.
NEW
Eastwood, M., Sailem, H., Marc, S., ..., Karteris, E. et al. (2023). MesoGraph: Automatic profiling of mesothelioma subtypes from histological images. Cell Reports Medicine, 2023, 4 (10), 101226, pp. 1 - 16. doi: 10.1016/j.xcrm.2023.101226.
NEW
Cullen, S., Mackay, R., Mohagheghi, A. and Du, X. (2023). Low-Cost Smartphone Photogrammetry Accurately Digitises Positive Socket and Limb Casts. Prosthesis, 5 (4), pp. 1382 - 1392. doi: 10.3390/prosthesis5040095.
NEW
Knight, M., Pels, N., Yadav, S., Elhelu, O., Parn, S., Rinaldi, G., Grigoriadis, D., Mann, V., Brindley, P. and Bridger, J. (2023). The human pathogen, Schistosoma mansoni, lacks the cognate sequence for human telomerase reverse transcriptase (hTERT) and relies on the snail host, Biomphalaria glabrata homologous enzyme for its intra-molluscan development. Research Square preprint, pp. 1 - xx. doi: 10.21203/rs.3.rs-3069723/v1.
NEW
Mo, Z., Wang, Q., Shi, H., Zhang, B. and Sui, W. (2023). Pointhuman: Reconstructing Clothed Human From Point Cloud Of Parametric Model. Computing and Informatics, 42 (2), pp. 457 - 479. doi: 10.31577/cai_2023_2_457.
NEW
Schmidt, A., Joshi, R., Gordillo-Marañón, M., ..., Drenos, F. et al. (2023). Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes. Schmidt, A.F., et al. (2023). 'Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes' in Communications Medicine., Vol. 3 (9)., pp.1 - 10. https://doi.org/10.1038/s43856-022-00234-0.
NEW
Rodrigues, A., Silva, S., Dias, I., ..., Pina, C. et al. (2024). Piplartine eliminates CD34+ AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling. Cell Death Discovery, 10, 147, pp. 1 - 16. doi: 10.1038/s41420-024-01909-4..
NEW
Pina, C. (2024). Contributions of transcriptional noise to leukaemia evolution: KAT2A as a case-study. Philosophical Transactions of the Royal Society B: Biological Sciences, 379 (1900), 20230052., pp. 1 - 11. doi: 10.1098/rstb.2023.0052.
NEW
Mudge, J., Carbonell-Sala, S., Diekhans, M., ..., Sisu, C. et al. (2024). GENCODE 2025: reference gene annotation for human and mouse. Mudge, J.M. et al (2025) 'GENCODE 2025: reference gene annotation for human and mouse', Nucleic Acids Research, 53 (D1), pp. D966 - D975. doi: 10.1093/nar/gkae1078.
NEW
Ogene, L., Woods, S., Hetmanski, J., Lozano, N., Karakasidi, A., Caswell, P., Kostarelos, K., Domingos, M., Vranic, S. and Kimber, S. (2024). Graphene oxide activates canonical TGFβ signalling in a human chondrocyte cell line via increased plasma membrane tension. Nanoscale, 16 (11), pp. 5653 - 5664. doi: 10.1039/d3nr06033k.
NEW
Amrenova, A., Baudin, C., Ostroumova, E., Stephens, J., Anderson, R. and Laurier, D. (2024). Intergenerational effects of ionizing radiation: review of recent studies from human data (2018–2021). International Journal of Radiation Biology, 100 (9), pp. 1253 - 1263. doi: 10.1080/09553002.2024.2309917.
NEW
Zagkos, L., Schwinges, A., Amin, H., Dovey, T. and Drenos, F. (2024). Exploring the contribution of lifestyle to the impact of education on the risk of cancer through Mendelian randomization analysis. Scientific Reports, 14 (1), 6074, pp. 1 - 10. doi: 10.1038/s41598-024-54259-7.
NEW
Lewis, A., Venugopal, B., Gandhi, V., Gibson, O., Swanton, L., Green, M., Bowen, J. and Polkey, M. (2024). Remote Vision-Based Digital Patient Monitoring of Pulse and Respiratory rates in Acute Medical Wards. Thorax, 0 (ahead of print), pp. 1 - 3. doi: 10.1136/thorax-2023-220968.
NEW
Orton, S., Karkia, R., Mustafov, D., ..., Karteris, E. et al. (2024). In Silico and In Vitro Mapping of Receptor-Type Protein Tyrosine Phosphatase Receptor Type D in Health and Disease: Implications for Asprosin Signalling in Endometrial Cancer and Neuroblastoma. Cancers, 16 (3), 582, pp. 1 - 19. doi: 10.3390/cancers16030582.
NEW
Mohamed, A., Fan, M., Bertolesi, E., Chen, H., Fu, Z. and Roberts, T. (2024). Microbial loading and self-healing in cementitious materials: A review of immobilisation techniques and materials. Materials and Design, 249, 113249, pp. 1 - 14. doi: 10.1016/j.matdes.2024.113249.
NEW
Britten, O. and Tosi, S. (2024). The role of diet in cancer: the potential of shaping public policy and clinical outcomes in the UK. Genes & Nutrition, 19, 15, pp. 1 - 15. doi: 10.1186/s12263-024-00750-9.
NEW
Philip, K., Buttery, S., Bowen, S., ..., Lewis, A. et al. (2024). Singing for lung health in COPD: a multicentre randomised controlled trial of online delivery. BMJ Open Respiratory Research, 11 (1), e002365, pp. 1 - 12. doi: 10.1136/bmjresp-2024-002365.
NEW
Al-dulaimi, S., Matta, S., Slijepcevic, P. and Roberts, T. (2024). 5-aza-2′-deoxycytidine induces telomere dysfunction in breast cancer cells. Al-dulaimi, S. et al. (2024) ‘5-aza-2′-deoxycytidine induces telomere dysfunction in breast cancer cells’, Biomedicine and Pharmacotherapy, 178, 117173, pp. 1 - 10. doi:https://doi.org/10.1016/j.biopha.2024.117173.
NEW
Klapwijk, J., Del Rio Espinola, A., Libertini, S., ..., Themis, M. et al. (2024). Improving the assessment of risk factors relevant to potential carcinogenicity of gene therapies: a consensus paper. Human Gene Therapy, 35 (15-16), pp. 527 - 542. doi: 10.1089/hum.2024.033.
NEW
Buttery, S., Lewis, A., Alzetani, A. et al. (2024). Survival following lung volume reduction procedures: results from the UK Lung Volume Reduction (UKLVR) registry. BMJ Open Respiratory Research, 11 (1), e002092, pp. 1 - 10 (+ 9 pp. of supplementary materials). doi: 10.1136/bmjresp-2023-002092.
NEW
Kaci, F., Lepore, A., Mohammad, A., Almarzouq, A., Craghill, I., Driessen, C., Besse, L., Bubici, C. and Papa, S. (2024). Targeting Fatty Acid Oxidation Pathways to Overcome Proteasome Inhibitor Resistance in Multiple Myeloma. Abstract book of the Josep Carreras Leukaemia Research Institute Symposium 2024: Updates on Genetics and Epigenetics of Haematological Malignancies: From Knowledge to Applications, Badalona, Barcelona, Spain, 20-22 November, pp. 73 - 73. Available at: https://www.carrerasresearch.org/rails/active_storage/blobs/redirect/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaHBBZ1VjIiwiZXhwIjpudWxsLCJwdXIiOiJibG9iX2lkIn19--119e85525af77eb3ffe663cb80141fe11890d039/Abstract%20Book_IJC%20Symposium%202024_compressed.pdf (accessed: 11 December 2024).
NEW
Stamatiou, K., Huguet, F., Serapinas, L., Spanos, C., Rappsilber, J. and Vagnarelli, P. (2024). Ki-67 is necessary during DNA replication for fork protection and genome stability. Genome Biology, 25 (1), pp. 1 - 33. doi: 10.1186/s13059-024-03243-5.
NEW
Stordal, B., Harvie, M., Antoniou, M., ..., Silva, E. et al. (2024). Breast cancer risk and prevention in 2024: An overview from the Breast Cancer UK - Breast Cancer Prevention Conference. Cancer Medicine, 2024, 13 (18), e70255, pp. 1 - 11. doi: 10.1002/cam4.70255.
NEW
Suleman, S., Fawaz, S., Roberts, T., Ellison, S., Bigger, B. and Themis, M. (2024). Optimised protocols to generate high titre lentiviral vectors using a novel transfection agent enabling extended HEK293T culture following transient transfection and suspension culture. Journal of Virological Methods, 325, 114884, pp. 1 - 9. doi: 10.1016/j.jviromet.2024.114884.
NEW
Kaur, G., Perteghella, T., Carbonell-Sala, S., ..., Sisu, C. et al. (2024). GENCODE: massively expanding the lncRNA catalog through capture long-read RNA sequencing. BioXriv [preprint] 2024.10.29.620654; doi: 10.1101/2024.10.29.620654.
NEW
Lawrence, K., Scholze, M., Seixo, J., Daley, F., Al-Haddad, E., Craenen, K., Gillham, C., Rake, C., Peto, J. and Anderson, R. (2024). M-FISH evaluation of chromosome aberrations to examine for historical exposure to ionising radiation due to participation at British nuclear test sites. Lawrence, K.J. et al. (2024) ‘M-FISH evaluation of chromosome aberrations to examine for historical exposure to ionising radiation due to participation at British nuclear test sites’, Journal of Radiological Protection, 44 (1), 011501, pp. 1 - 18. doi: 10.1088/1361-6498/ad1743.
NEW
Chen, H., Zhang, B. and Huang, J. (2024). Recent advances and applications of artificial intelligence in 3D bioprinting. Biophysics Reviews, 5 (3), 031301. doi: 10.1063/5.0190208.
NEW
Kanso, N., Hashimi, M., Amin, H., Day, A. and Drenos, F. (2024). No Evidence That Vitamin D Levels or Deficiency Are Associated with the Risk of Open-Angle Glaucoma in Individuals of European Ancestry: A Mendelian Randomisation Analysis. Genes, 15 (8), 1084, pp. 1 - 12. doi: 10.3390/genes15081084.
NEW
Stephens, J., Moorhouse, A., Craenen, K., Schroeder, E., Drenos, F. and Anderson, R. (2024). A systematic review of human evidence for the intergenerational effects of exposure to ionizing radiation. International Journal of Radiation Biology, 100 (9), pp. 1330 - 1363. doi: 10.1080/09553002.2024.2306328.
NEW
Osório, L., Naveenathayalan, A., Silva, E. and Mackay, R. (2024). Fibroblastic tissue growth on polymeric electrospun membranes: a feasibility study. Discover Applied Sciences, 6, 350, pp. 1 - 21. doi: 10.1007/s42452-024-06038-2.
NEW
Hablase, R., Kyrou, I., Randeva, H., Karteris, E. and Chatterjee, J. (2024). The “Road” to Malignant Transformation from Endometriosis to Endometriosis-Associated Ovarian Cancers (EAOCs): An mTOR-Centred Review. Cancers, 16 (11), 2160, pp. 1 - 28. doi: 10.3390/cancers16112160.
NEW
Garimberti, E., Federico, C., Ragusa, D., Bruno, F., Saccone, S., Bridger, J. and Tosi, S. (2024). Alterations in Genome Organization in Lymphoma Cell Nuclei due to the Presence of the t(14;18) Translocation.
NEW
Mokbel, K., Kodresko, A., Trembley, J. and Jouhara, H. (2024). Therapeutic Effect of Superficial Scalp Hypothermia on Chemotherapy-Induced Alopecia in Breast Cancer Survivors. Journal of Clinical Medicine, 13 (18), 5397, pp. 1 - 17. doi: 10.3390/jcm13185397.
NEW
Beausoleil, C., Thébault, A., Andersson, P., ..., Ermler, S. et al. (2024). Weight of evidence evaluation of the metabolism disrupting effects of triphenyl phosphate using an expert knowledge elicitation approach. Toxicology and Applied Pharmacology, 489, 116995, pp. 1 - 16. doi: 10.1016/j.taap.2024.116995.
NEW
Morea, A., Saravi, S., Sisu, C., Hall, M., Tosi, S., Karteris, E. and Storlazzi, C. (2024). Effect of MYC and PARP Inhibitors in Ovarian Cancer Using an In Vitro Model. Anticancer Research: international journal of cancer research and treatment, 44 (5) pp. 1817 - 1827. doi: 10.21873/anticanres.16983.
NEW
Zhang, B., Morgan, M., Teoh, X., Mackay, R., Ermler, S. and Narayan, R. (2024). Recent Advances in 3D printing for in vitro cancer models. Zhang, B. et al. (2024). ‘Recent advances in 3D printing for in vitro cancer models’ in Journal of Applied Physics. Vol.135 (14)., pp.1 - 19. DOI:https://doi.org/10.1063/5.0200726.
NEW
Zhang, B., Xu, L., Liu, K., Yang, R., Li, M. and Guo, X. (2024). Piecewise convolutional neural network relation extraction with self-attention mechanism. Pattern Recognition, 159, 111083, pp. 1 - 10. doi: 10.1016/j.patcog.2024.111083.
NEW
Lewis, A., Turner, L., Fryer, S., Smith, R., Dillarstone, H., Patrick, Y. and Bevan-Smith, E. (2024). The acceptability, practicality, implementation and efficacy of a physical and social activity intervention ‘BreatheHappy’ for people with long-term respiratory conditions: A feasibility study. Chronic Respiratory Disease, 21, pp. 1 - 15. doi: 10.1177/14799731241238435.
NEW
Clarkson, E. and Lewis, A. (2024). BMP antagonist CHRDL2 enhances the cancer stem cell phenotype and increases chemotherapy resistance in Colorectal Cancer. bioRxiv [preprint], 2024.01.23.576664, pp. 1 - [38]. doi: 10.1101/2024.01.23.576664.
NEW
Hashimi, M., Amin, H., Zagkos, L., Day, A. and Drenos, F. (2024). Using genetics to investigate the association between lanosterol and cataract. Frontiers in Genetics, 15, 1231521, pp. 1 - 8. doi: 10.3389/fgene.2024.1231521.
NEW
Mokbel, K., Kodresko, A., Ghazal, H., Mokbel, R., Trembley, J. and Jouhara, H. (2024). Cryogenic Media in Biomedical Applications: Current Advances, Challenges, and Future Perspectives. Mokbel, K. et al (2023) 'Cryogenic Media in Biomedical Applications: Current Advances, Challenges, and Future Perspectives', In Vivo, 38 (1), pp. 1 - 39. doi: 10.21873/invivo.13407.
NEW
Baines, S., Otermans, P., Tree, D. and Worsfold, N. (2024). Measuring and mapping authentic assessment with a novel quantitative typology. Baines, S. et al. (2025) 'Measuring and mapping authentic assessment with a novel quantitative typology', Teaching in Higher Education, 30 (3), pp. 663 - 682. doi: 10.1080/13562517.2024.2424823.
NEW
Wang, Z., Zhang, B., Yang, R., Guo, C. and Li, M. (2024). DAGCN: Distance-based and Aspect-oriented Graph Convolutional Network for Aspect-based Sentiment Analysis. in Duh, K., Gomez, H. and Bethard, S. (eds.) Findings of the Association for Computational Linguistics: NAACL 2024 - Findings, Mexico City, Mexico, 16-21 June, pp. 1863 - 1876. Available at: https://aclanthology.org/2024.findings-naacl.120/ (Accessed: 26 July 2024).
NEW
Mustafov, D., Siddiqui, S., Klena, L., Karteris, E. and Braoudaki, M. (2024). SV2B/miR-34a/miR-128 axis as prognostic biomarker in glioblastoma multiforme. Scientific Reports, 14 (1), 6647, pp. 1 - 13. doi: 10.1038/s41598-024-55917-6.
NEW
Perira Torres, R., Samarakone, C., Bridger, J. and de Castro, I. (2024). Pushing the envelope – How the genome interacts with the nuclear envelope in health and disease. Perira Torres, R. et al. (2025) 'Pushing the envelope – How the genome interacts with the nuclear envelope in health and disease', in R. Donev (ed.) Advances in Protein Chemistry and Structural Biology: Nuclear Proteins. Amsterdam: Academic Press, pp. 155 - 190. doi: 10.1016/bs.apcsb.2024.09.007.
NEW
Zhang, B., Sui, W., Huang, Z., Li, M. and Qi, M. (2024). Normalizing flow based uncertainty estimation for deep regression analysis. Neurocomputing, 585, 127645, pp. 1 - 9. doi: 10.1016/j.neucom.2024.127645.
NEW
Tree, D. and Worsfold, N. (2026). Do Synoptic Assessments Lead to Authentic Learning? A Critical Perspective on Integration and Intentionality in Higher Education Assessment Design. Education Sciences, 16 (2), 187, pp. 1–15. doi: 10.3390/educsci16020187.
NEW
Pereira, A., Moetazedian, A., Taylor, M., Longbottom, F., Ghazal, H., Han, J. and Zhang, B. (2026). Design and Material Characterisation of Additively Manufactured Polymer Scaffolds for Medical Devices. Journal of Manufacturing and Materials Processing, 10 (1), 39, pp. 1 - 21. doi: 10.3390/jmmp10010039.
NEW
Stephens, J., Ermler, S., Rake, C., Sisu, C., Scholze, M. and Anderson, R. (2026). Limited evidence for transgenerational chromosomal instability in families with elevated mutation pattern SBS16 in the germline. International Journal of Radiation Biology, 0 (ahead of print), pp. 1 - 10. doi: 10.1080/09553002.2026.2618529.
NEW
Lewis, A., Jung, P., Williams, P. et al. (2026). Singing for lung health following completion of pulmonary rehabilitation: feasibility of a randomised controlled trial. BMJ Open Respiratory Research, 13 (1), e003236, pp. 1 - 13. doi: 10.1136/bmjresp-2025-003236.

2026

NEW Pereira, A., Moetazedian, A., Taylor, M., Longbottom, F., Ghazal, H., Han, J. and Zhang, B. (2026). Design and Material Characterisation of Additively Manufactured Polymer Scaffolds for Medical Devices. Journal of Manufacturing and Materials Processing, 10 (1), 39, pp. 1 - 21. doi: 10.3390/jmmp10010039.

DOI BRAD record
NEW Tree, D. and Worsfold, N. (2026). Do Synoptic Assessments Lead to Authentic Learning? A Critical Perspective on Integration and Intentionality in Higher Education Assessment Design. Education Sciences, 16 (2), 187, pp. 1–15. doi: 10.3390/educsci16020187.

DOI BRAD record
NEW Stephens, J., Ermler, S., Rake, C., Sisu, C., Scholze, M. and Anderson, R. (2026). Limited evidence for transgenerational chromosomal instability in families with elevated mutation pattern SBS16 in the germline. International Journal of Radiation Biology, 0 (ahead of print), pp. 1 - 10. doi: 10.1080/09553002.2026.2618529.

DOI BRAD record
NEW Lewis, A., Jung, P., Williams, P. et al. (2026). Singing for lung health following completion of pulmonary rehabilitation: feasibility of a randomised controlled trial. BMJ Open Respiratory Research, 13 (1), e003236, pp. 1 - 13. doi: 10.1136/bmjresp-2025-003236.

DOI BRAD record

2025

NEW Sammy, A., Karteris, E., Riyahi, K. and Bridger, J. (2025). Alterations in Interphase Chromosome Positioning and Nuclear Myosin Iβ and VI in Ovarian Cancer Cells, and the Reversal of Cisplatin Chemo resistance upon knock-down of Nuclear Myosin Iβ. Chromosome Research, 0 (in submission).

BRAD record
NEW Suleman, S., Khalifa, M., Fawaz, S., Alhaque, S., Chinea, Y. and Themis, M. (2025). Analysis of HIV-1 based lentiviral vector particle composition by PacBio long-read nucleic acid sequencing. Human Gene Therapy, 0 (accepted, in press), pp. 1 - 9. doi: 10.1089/hum.2024.121.

DOI BRAD record
NEW Clarkson, E. and Lewis, A. (2025). BMP antagonist CHRDL2 enhances the cancer stem-cell phenotype and increases chemotherapy resistance in colorectal cancer. Molecular Oncology, 0 (ahead of print), pp. 1 - 21. doi: 10.1002/1878-0261.70064.

DOI BRAD record
NEW Clarkson, E. and Lewis, A. (2025). BMP signalling in colorectal cancer; the yin to WNTs yang. Journal of Pathology, 266 (3), pp. 280 - 291. doi: 10.1002/path.6428.

DOI BRAD record
NEW Esentürk, E., Sahli, A., Haberland, V. et al. (2025). Causes of evolutionary divergence in prostate cancer. arXiv preprint, arXiv:2503.13189v1 [q-bio.GN, pp. 1 - 23. doi: 10.48550/arXiv.2503.13189.

DOI BRAD record
NEW Mokbel, R., Kodresko, A., Mokbel, K., Ghazal, H., Trembley, J. and Jouhara, H. (2025). Cutaneous Cryosurgery in Dermatology: Evolving Principles and Clinical Applications for Benign, Premalignant, and Malignant Lesions. Mokbel, R. et al. (2025) ‘Cutaneous Cryosurgery in Dermatology: Evolving Principles and Clinical Applications for Benign, Premalignant, and Malignant Lesions’, In Vivo, 39 (2), pp. 577 - 612. doi: 10.21873/invivo.13865.

DOI BRAD record
NEW Karkia, R., Sisu, C., Saravi, S., Kyrou, I., Randeva, H., Chatterjee, J. and Karteris, E. (2025). Effects of Asprosin and Role of TLR4 as a Biomarker in Endometrial Cancer. Molecules, 30 (16), 3410, pp. 1 - 27. doi: 10.3390/molecules30163410.

DOI BRAD record
NEW Filipe, A., Saravi, S., Mustafov, D., ..., Drenos, F., Sisu, C., Karteris, E. et al. (2025). Emerging roles of the cancerous inhibitor of protein phosphatase 2A (CIP2A) in ovarian cancer. Scientific Reports, 15, 22382, pp. 1 - 15. doi: 10.1038/s41598-025-05013-0.

DOI BRAD record
NEW Al-dulaimi, S., Thomas, R., Matta, S. and Roberts, T. (2025). Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity. Biogerontology, 26 (5), 178, pp. 1 - 14. doi: 10.1007/s10522-025-10315-x.

DOI BRAD record
NEW Hashimi, M., Amin, H., Day, A. and Drenos, F. (2025). Exploring the causal relationship between vitamin D levels and deficiency with the risk of cataract: A Mendelian Randomisation study. Ophthalmic Research, 0 (ahead of print), pp. 1 - 18. doi: 10.1159/000545332.

DOI BRAD record
NEW Ber, S., Yang, M., Sciacovelli, M., ..., Esposito, A. et al. (2025). FOXO1 links KRAS G12D and G12V alleles to glutamine and nitrogen metabolism in colorectal cancer. EMBO Reports, 0 (early online), pp. 1 - 21. doi: 10.1038/s44319-025-00641-z.

DOI BRAD record
NEW Panraksa, P., Jantrawut, P., Teoh, X., Sengtakdaed, K., Pornngam, P., Chaiwarit, T., Chantadee, T., Jantanasakulwong, K., Udomsom, S. and Zhang, B. (2025). Formulation and Structural Optimisation of PVA-Fibre Biopolymer Composites for 3D Printing in Drug Delivery Applications. Polymers, 17 (18), 2502, pp. 1 - 24. doi: 10.3390/polym17182502.

DOI BRAD record
NEW Harvey, A. and Tree, D. (2025). From silos to synthesis: ensuring interdisciplinary education through synoptic assessment. Biochemist, 47 (1), pp. 27 - 34. doi: 10.1042/bio_2025_104.

DOI BRAD record
NEW Kabella, N., Bayer, F., Stamatiou, K., ..., Vagnarelli, P. et al. (2025). Illuminating oncogenic KRAS signaling by multi-dimensional chemical proteomics. bioRxiv preprint, pp. 1 - 27. doi: 10.1101/2025.01.30.635627.

DOI BRAD record
NEW Poonawala, K. and Zhang, B. (2025). Influence of 3D printing process parameters and design on mechanical properties of tissue scaffolds. MATEC Web of Conferences, 413, 08003, pp. 1 - 5. doi: 10.1051/matecconf/202541308003.

DOI BRAD record
NEW Chen, L., Zhang, Y., Chen, G., Li, J., Zhang, B. and Wang, M. (2025). Influence of typical technological parameters on the processing quality of laser surface texturing technology for finger sealing. Surface Topography: Metrology and Properties, 13 (1), 015008, pp. 1 - 18. doi: 10.1088/2051-672X/ad993e.

DOI BRAD record
NEW Tree, D., Harvey, A. and Rand-Weaver, M. (2025). Integrated Programme Assessment: 10 years on. Open Scholarship of Teaching and Learning, 2025, 4 (1), pp. 166 - 180 doi: 10.56230/osotl.128

DOI BRAD record
NEW Cullen, S., Mohagheghi, A. and Mackay, R. (2025). Investigating the accuracy of smartphone photogrammetry for remote 3D scanning transtibial amputees. Journal of Medical Engineering and Technology, 0 (ahead of print), pp. 1 - 11. doi: 10.1080/03091902.2025.2540096.

DOI BRAD record
NEW James, E., Teh, M., Li, Y., ..., Roberts, T., Lewis, A. et al. (2025). Membrane transporter progressive ankylosis protein homologue (ANKH/Ank) partially mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation, and ageing. Frontiers in Aging, 6, 1583288, pp. 1 - 28. doi: 10.3389/fragi.2025.1583288.

DOI BRAD record
NEW Payoe, K., Gadar, K., Flahaut, E., McCarthy, R. and Stenbeck, G. (2025). Nanoparticle-induced systemic toxicity and immune response in Galleria mellonella larvae. Frontiers in Pharmacology, 16, 1625472, pp. 1 - 14. doi: 10.3389/fphar.2025.1625472.

DOI BRAD record
NEW Ryan, J., Burke, J., Byrne, R., Capellari, E., Harvey, A., O'Connell, N., Omichinski, D., Rodby-Bousquet, E., Peterson, M. and The Adult CP Clinical Practice Guideline Working Group (2025). Pain in adults with cerebral palsy: A systematic review. Developmental Medicine and Child Neurology, 67 (7), pp. 854 - 874. doi: 10.1111/dmcn.16254.

DOI BRAD record
NEW Zhang, B., da Silva, M., Johnston, I., Aspinall, S. and Cook, M. (2025). Poly(vinyl alcohol)‐Agar Double Network Hydrogels: Linking Formulation to Mechanical and Rheological Properties. Macromolecular Chemistry and Physics, 226 (24), e00257, pp. 1 - 9. doi: 10.1002/macp.202500257.

DOI BRAD record
NEW Futema, M., Ingegneri, T., Sharifi, M., Drenos, F. and Humphries, S. (2025). Polygenic predisposition to increased LDL-cholesterol concentration and Carotid Artery Intima Media Thickness in childhood and early adulthood. Atherosclerosis Plus, 62 (Supplement), pp. 3 - 3. doi: 10.1016/j.athplu.2025.10.004.

DOI BRAD record
NEW Collinson, R. and Tanos, B. (2025). Primary cilia and cancer: a tale of many faces. Oncogene, 44 (21), pp. 1551 - 1566. doi: 10.1038/s41388-025-03416-x.

DOI BRAD record
NEW Kabella, N., Bayer, F., Stamatiou, K., ..., Vagnarelli, P. et al. (2025). Proteomic analyses identify targets, pathways, and cellular consequences of oncogenic KRAS signaling. Science Signaling, 18 (897), eadt6552, pp. 1 - 51. doi: 10.1126/scisignal.adt6552.

DOI BRAD record
NEW Ahmed, O., Wang, M., Zhang, B., Irving, R., Begg, P. and Du, X. (2025). Robotic Systems for Cochlear Implant Surgeries: A Review of Robotic Design and Clinical Outcomes. Electronics, 14 (13), 2685, pp. 1 - 27. doi: 10.3390/electronics14132685.

DOI BRAD record
NEW Vagnarelli, P. (2025). The 10th Nuclear Envelope and Chromatin Organisation UK meeting. 3–4 October 2024, Brunel University London. Biochemist, 47 (1), pp. 59 - 59. doi: 10.1042/bio_2024_938.

DOI BRAD record
NEW Karkia, R., MacCarthy, G., Payne, A., Karteris, E., Pazoki, R. and Chatterjee, J. (2025). The Association Between Metabolic Syndrome and the Risk of Endometrial Cancer in Pre- and Post-Menopausal Women: A UK Biobank Study. Journal of Clinical Medicine, 14 (3), 751, pp. 1 - 15. doi: 10.3390/jcm14030751.

DOI BRAD record
NEW Suleman, S., Alhaque, S., Guo, A., Zhang, A., Fawaz, S., Perera, S., Khalifa, M., Rashidi, H., Hay, D. and Themis, M. (2025). Transcriptomic Profiling of iPS Cell-Derived Hepatocyte-like Cells Reveals Their Close Similarity to Primary Liver Hepatocytes. Cells, 14 (12), 925, pp. 1 - 19. doi: 10.3390/cells14120925.

DOI BRAD record
NEW Suleman, S., Alhaque, S., Guo, A., ..., Payne, A., Themis, M. et al. (2025). hInGeTox: a human-based in vitro platform to evaluate lentivirus/host interactions that contribute to genotoxicity. Gene Therapy, 32 (6), pp. 641 - 656. doi: 10.1038/s41434-025-00550-9.

DOI BRAD record

2024

NEW Al-dulaimi, S., Matta, S., Slijepcevic, P. and Roberts, T. (2024). 5-aza-2′-deoxycytidine induces telomere dysfunction in breast cancer cells. Al-dulaimi, S. et al. (2024) ‘5-aza-2′-deoxycytidine induces telomere dysfunction in breast cancer cells’, Biomedicine and Pharmacotherapy, 178, 117173, pp. 1 - 10. doi:https://doi.org/10.1016/j.biopha.2024.117173.

DOI BRAD record
NEW Stephens, J., Moorhouse, A., Craenen, K., Schroeder, E., Drenos, F. and Anderson, R. (2024). A systematic review of human evidence for the intergenerational effects of exposure to ionizing radiation. International Journal of Radiation Biology, 100 (9), pp. 1330 - 1363. doi: 10.1080/09553002.2024.2306328.

DOI BRAD record
NEW Garimberti, E., Federico, C., Ragusa, D., Bruno, F., Saccone, S., Bridger, J. and Tosi, S. (2024). Alterations in Genome Organization in Lymphoma Cell Nuclei due to the Presence of the t(14;18) Translocation.

BRAD record
NEW Clarkson, E. and Lewis, A. (2024). BMP antagonist CHRDL2 enhances the cancer stem cell phenotype and increases chemotherapy resistance in Colorectal Cancer. bioRxiv [preprint], 2024.01.23.576664, pp. 1 - [38]. doi: 10.1101/2024.01.23.576664.

DOI BRAD record
NEW Stordal, B., Harvie, M., Antoniou, M., ..., Silva, E. et al. (2024). Breast cancer risk and prevention in 2024: An overview from the Breast Cancer UK - Breast Cancer Prevention Conference. Cancer Medicine, 2024, 13 (18), e70255, pp. 1 - 11. doi: 10.1002/cam4.70255.

DOI BRAD record
NEW Pina, C. (2024). Contributions of transcriptional noise to leukaemia evolution: KAT2A as a case-study. Philosophical Transactions of the Royal Society B: Biological Sciences, 379 (1900), 20230052., pp. 1 - 11. doi: 10.1098/rstb.2023.0052.

DOI BRAD record
NEW Mokbel, K., Kodresko, A., Ghazal, H., Mokbel, R., Trembley, J. and Jouhara, H. (2024). Cryogenic Media in Biomedical Applications: Current Advances, Challenges, and Future Perspectives. Mokbel, K. et al (2023) 'Cryogenic Media in Biomedical Applications: Current Advances, Challenges, and Future Perspectives', In Vivo, 38 (1), pp. 1 - 39. doi: 10.21873/invivo.13407.

DOI BRAD record
NEW Wang, Z., Zhang, B., Yang, R., Guo, C. and Li, M. (2024). DAGCN: Distance-based and Aspect-oriented Graph Convolutional Network for Aspect-based Sentiment Analysis. in Duh, K., Gomez, H. and Bethard, S. (eds.) Findings of the Association for Computational Linguistics: NAACL 2024 - Findings, Mexico City, Mexico, 16-21 June, pp. 1863 - 1876. Available at: https://aclanthology.org/2024.findings-naacl.120/ (Accessed: 26 July 2024).

BRAD record
NEW Morea, A., Saravi, S., Sisu, C., Hall, M., Tosi, S., Karteris, E. and Storlazzi, C. (2024). Effect of MYC and PARP Inhibitors in Ovarian Cancer Using an In Vitro Model. Anticancer Research: international journal of cancer research and treatment, 44 (5) pp. 1817 - 1827. doi: 10.21873/anticanres.16983.

DOI BRAD record
NEW Zagkos, L., Schwinges, A., Amin, H., Dovey, T. and Drenos, F. (2024). Exploring the contribution of lifestyle to the impact of education on the risk of cancer through Mendelian randomization analysis. Scientific Reports, 14 (1), 6074, pp. 1 - 10. doi: 10.1038/s41598-024-54259-7.

DOI BRAD record
NEW Osório, L., Naveenathayalan, A., Silva, E. and Mackay, R. (2024). Fibroblastic tissue growth on polymeric electrospun membranes: a feasibility study. Discover Applied Sciences, 6, 350, pp. 1 - 21. doi: 10.1007/s42452-024-06038-2.

DOI BRAD record
NEW Mudge, J., Carbonell-Sala, S., Diekhans, M., ..., Sisu, C. et al. (2024). GENCODE 2025: reference gene annotation for human and mouse. Mudge, J.M. et al (2025) 'GENCODE 2025: reference gene annotation for human and mouse', Nucleic Acids Research, 53 (D1), pp. D966 - D975. doi: 10.1093/nar/gkae1078.

DOI BRAD record
NEW Kaur, G., Perteghella, T., Carbonell-Sala, S., ..., Sisu, C. et al. (2024). GENCODE: massively expanding the lncRNA catalog through capture long-read RNA sequencing. BioXriv [preprint] 2024.10.29.620654; doi: 10.1101/2024.10.29.620654.

DOI BRAD record
NEW Ogene, L., Woods, S., Hetmanski, J., Lozano, N., Karakasidi, A., Caswell, P., Kostarelos, K., Domingos, M., Vranic, S. and Kimber, S. (2024). Graphene oxide activates canonical TGFβ signalling in a human chondrocyte cell line via increased plasma membrane tension. Nanoscale, 16 (11), pp. 5653 - 5664. doi: 10.1039/d3nr06033k.

DOI BRAD record
NEW Klapwijk, J., Del Rio Espinola, A., Libertini, S., ..., Themis, M. et al. (2024). Improving the assessment of risk factors relevant to potential carcinogenicity of gene therapies: a consensus paper. Human Gene Therapy, 35 (15-16), pp. 527 - 542. doi: 10.1089/hum.2024.033.

DOI BRAD record
NEW Orton, S., Karkia, R., Mustafov, D., ..., Karteris, E. et al. (2024). In Silico and In Vitro Mapping of Receptor-Type Protein Tyrosine Phosphatase Receptor Type D in Health and Disease: Implications for Asprosin Signalling in Endometrial Cancer and Neuroblastoma. Cancers, 16 (3), 582, pp. 1 - 19. doi: 10.3390/cancers16030582.

DOI BRAD record
NEW Amrenova, A., Baudin, C., Ostroumova, E., Stephens, J., Anderson, R. and Laurier, D. (2024). Intergenerational effects of ionizing radiation: review of recent studies from human data (2018–2021). International Journal of Radiation Biology, 100 (9), pp. 1253 - 1263. doi: 10.1080/09553002.2024.2309917.

DOI BRAD record
NEW Stamatiou, K., Huguet, F., Serapinas, L., Spanos, C., Rappsilber, J. and Vagnarelli, P. (2024). Ki-67 is necessary during DNA replication for fork protection and genome stability. Genome Biology, 25 (1), pp. 1 - 33. doi: 10.1186/s13059-024-03243-5.

DOI BRAD record
NEW Lawrence, K., Scholze, M., Seixo, J., Daley, F., Al-Haddad, E., Craenen, K., Gillham, C., Rake, C., Peto, J. and Anderson, R. (2024). M-FISH evaluation of chromosome aberrations to examine for historical exposure to ionising radiation due to participation at British nuclear test sites. Lawrence, K.J. et al. (2024) ‘M-FISH evaluation of chromosome aberrations to examine for historical exposure to ionising radiation due to participation at British nuclear test sites’, Journal of Radiological Protection, 44 (1), 011501, pp. 1 - 18. doi: 10.1088/1361-6498/ad1743.

DOI BRAD record
NEW Baines, S., Otermans, P., Tree, D. and Worsfold, N. (2024). Measuring and mapping authentic assessment with a novel quantitative typology. Baines, S. et al. (2025) 'Measuring and mapping authentic assessment with a novel quantitative typology', Teaching in Higher Education, 30 (3), pp. 663 - 682. doi: 10.1080/13562517.2024.2424823.

DOI BRAD record
NEW Mohamed, A., Fan, M., Bertolesi, E., Chen, H., Fu, Z. and Roberts, T. (2024). Microbial loading and self-healing in cementitious materials: A review of immobilisation techniques and materials. Materials and Design, 249, 113249, pp. 1 - 14. doi: 10.1016/j.matdes.2024.113249.

DOI BRAD record
NEW Kanso, N., Hashimi, M., Amin, H., Day, A. and Drenos, F. (2024). No Evidence That Vitamin D Levels or Deficiency Are Associated with the Risk of Open-Angle Glaucoma in Individuals of European Ancestry: A Mendelian Randomisation Analysis. Genes, 15 (8), 1084, pp. 1 - 12. doi: 10.3390/genes15081084.

DOI BRAD record
NEW Zhang, B., Sui, W., Huang, Z., Li, M. and Qi, M. (2024). Normalizing flow based uncertainty estimation for deep regression analysis. Neurocomputing, 585, 127645, pp. 1 - 9. doi: 10.1016/j.neucom.2024.127645.

DOI BRAD record
NEW Suleman, S., Fawaz, S., Roberts, T., Ellison, S., Bigger, B. and Themis, M. (2024). Optimised protocols to generate high titre lentiviral vectors using a novel transfection agent enabling extended HEK293T culture following transient transfection and suspension culture. Journal of Virological Methods, 325, 114884, pp. 1 - 9. doi: 10.1016/j.jviromet.2024.114884.

DOI BRAD record
NEW Zhang, B., Xu, L., Liu, K., Yang, R., Li, M. and Guo, X. (2024). Piecewise convolutional neural network relation extraction with self-attention mechanism. Pattern Recognition, 159, 111083, pp. 1 - 10. doi: 10.1016/j.patcog.2024.111083.

DOI BRAD record
NEW Rodrigues, A., Silva, S., Dias, I., ..., Pina, C. et al. (2024). Piplartine eliminates CD34+ AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling. Cell Death Discovery, 10, 147, pp. 1 - 16. doi: 10.1038/s41420-024-01909-4..

DOI BRAD record
NEW Perira Torres, R., Samarakone, C., Bridger, J. and de Castro, I. (2024). Pushing the envelope – How the genome interacts with the nuclear envelope in health and disease. Perira Torres, R. et al. (2025) 'Pushing the envelope – How the genome interacts with the nuclear envelope in health and disease', in R. Donev (ed.) Advances in Protein Chemistry and Structural Biology: Nuclear Proteins. Amsterdam: Academic Press, pp. 155 - 190. doi: 10.1016/bs.apcsb.2024.09.007.

DOI BRAD record
NEW Zhang, B., Morgan, M., Teoh, X., Mackay, R., Ermler, S. and Narayan, R. (2024). Recent Advances in 3D printing for in vitro cancer models. Zhang, B. et al. (2024). ‘Recent advances in 3D printing for in vitro cancer models’ in Journal of Applied Physics. Vol.135 (14)., pp.1 - 19. DOI:https://doi.org/10.1063/5.0200726.

DOI BRAD record
NEW Chen, H., Zhang, B. and Huang, J. (2024). Recent advances and applications of artificial intelligence in 3D bioprinting. Biophysics Reviews, 5 (3), 031301. doi: 10.1063/5.0190208.

DOI BRAD record
NEW Lewis, A., Venugopal, B., Gandhi, V., Gibson, O., Swanton, L., Green, M., Bowen, J. and Polkey, M. (2024). Remote Vision-Based Digital Patient Monitoring of Pulse and Respiratory rates in Acute Medical Wards. Thorax, 0 (ahead of print), pp. 1 - 3. doi: 10.1136/thorax-2023-220968.

DOI BRAD record
NEW Mustafov, D., Siddiqui, S., Klena, L., Karteris, E. and Braoudaki, M. (2024). SV2B/miR-34a/miR-128 axis as prognostic biomarker in glioblastoma multiforme. Scientific Reports, 14 (1), 6647, pp. 1 - 13. doi: 10.1038/s41598-024-55917-6.

DOI BRAD record
NEW Philip, K., Buttery, S., Bowen, S., ..., Lewis, A. et al. (2024). Singing for lung health in COPD: a multicentre randomised controlled trial of online delivery. BMJ Open Respiratory Research, 11 (1), e002365, pp. 1 - 12. doi: 10.1136/bmjresp-2024-002365.

DOI BRAD record
NEW Buttery, S., Lewis, A., Alzetani, A. et al. (2024). Survival following lung volume reduction procedures: results from the UK Lung Volume Reduction (UKLVR) registry. BMJ Open Respiratory Research, 11 (1), e002092, pp. 1 - 10 (+ 9 pp. of supplementary materials). doi: 10.1136/bmjresp-2023-002092.

DOI BRAD record
NEW Kaci, F., Lepore, A., Mohammad, A., Almarzouq, A., Craghill, I., Driessen, C., Besse, L., Bubici, C. and Papa, S. (2024). Targeting Fatty Acid Oxidation Pathways to Overcome Proteasome Inhibitor Resistance in Multiple Myeloma. Abstract book of the Josep Carreras Leukaemia Research Institute Symposium 2024: Updates on Genetics and Epigenetics of Haematological Malignancies: From Knowledge to Applications, Badalona, Barcelona, Spain, 20-22 November, pp. 73 - 73. Available at: https://www.carrerasresearch.org/rails/active_storage/blobs/redirect/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaHBBZ1VjIiwiZXhwIjpudWxsLCJwdXIiOiJibG9iX2lkIn19--119e85525af77eb3ffe663cb80141fe11890d039/Abstract%20Book_IJC%20Symposium%202024_compressed.pdf (accessed: 11 December 2024).

BRAD record
NEW Lewis, A., Turner, L., Fryer, S., Smith, R., Dillarstone, H., Patrick, Y. and Bevan-Smith, E. (2024). The acceptability, practicality, implementation and efficacy of a physical and social activity intervention ‘BreatheHappy’ for people with long-term respiratory conditions: A feasibility study. Chronic Respiratory Disease, 21, pp. 1 - 15. doi: 10.1177/14799731241238435.

DOI BRAD record
NEW Britten, O. and Tosi, S. (2024). The role of diet in cancer: the potential of shaping public policy and clinical outcomes in the UK. Genes & Nutrition, 19, 15, pp. 1 - 15. doi: 10.1186/s12263-024-00750-9.

DOI BRAD record
NEW Hablase, R., Kyrou, I., Randeva, H., Karteris, E. and Chatterjee, J. (2024). The “Road” to Malignant Transformation from Endometriosis to Endometriosis-Associated Ovarian Cancers (EAOCs): An mTOR-Centred Review. Cancers, 16 (11), 2160, pp. 1 - 28. doi: 10.3390/cancers16112160.

DOI BRAD record
NEW Mokbel, K., Kodresko, A., Trembley, J. and Jouhara, H. (2024). Therapeutic Effect of Superficial Scalp Hypothermia on Chemotherapy-Induced Alopecia in Breast Cancer Survivors. Journal of Clinical Medicine, 13 (18), 5397, pp. 1 - 17. doi: 10.3390/jcm13185397.

DOI BRAD record
NEW Hashimi, M., Amin, H., Zagkos, L., Day, A. and Drenos, F. (2024). Using genetics to investigate the association between lanosterol and cataract. Frontiers in Genetics, 15, 1231521, pp. 1 - 8. doi: 10.3389/fgene.2024.1231521.

DOI BRAD record
NEW Beausoleil, C., Thébault, A., Andersson, P., ..., Ermler, S. et al. (2024). Weight of evidence evaluation of the metabolism disrupting effects of triphenyl phosphate using an expert knowledge elicitation approach. Toxicology and Applied Pharmacology, 489, 116995, pp. 1 - 16. doi: 10.1016/j.taap.2024.116995.

DOI BRAD record

2023

NEW Cullen, S., Mackay, R., Mohagheghi, A. and Du, X. (2023). 3D Motion Analysis for the Assessment of Dynamic Coupling in Transtibial Prosthetics: A Proof of Concept. IEEE Open Journal of Engineering in Medicine and Biology, 4, pp. 141 - 147. doi: 10.1109/ojemb.2023.3296978.

DOI BRAD record
NEW Zhang, B., Lu, Y., Yong, R., Zou, G., Yang, R., Pan, J. and Li, M. (2023). A spatial correlation prediction model of urban PM2.5 concentration based on deconvolution and LSTM. Neurocomputing, 0 (accepted, in press), pp. [1] - [15].

BRAD record
NEW Schreglmann, S., Goncalves, T., Grant‐Peters, M., Kia, D., Soreq, L., Ryten, M., Wood, N., Bhatia, K. and Tomita, K. (2023). Age‐related telomere attrition in the human putamen. Aging Cell, 0 (ahead-of-print), e13861, pp. 1 - 14. doi: 10.1111/acel.13861.

DOI BRAD record
NEW Lepore, A., Kaci, F., Bubici, C. and Papa, S. (2023). An Integrated Methodology to Quantify the Glycolytic Stress in Plasma Cell Myeloma in Response to Cytotoxic Drugs. in Papa, S. and Bubici, C. (eds.) Methods in Molecular Biology, 2675, pp. 285 - 296. doi: 10.1007/978-1-0716-3247-5_21.

DOI BRAD record
NEW Zhang, B., Belton, P., Teoh, X., Gleadall, A., Bibb, R. and Qi, S. (2023). An investigation into the effects of ink formulations of semi-solid syringe extrusion 3D printing on the performance of the printed solid dosage forms. Zhang, B. et al. (2023) ‘An investigation into the effects of ink formulations of semi-solid syringe extrusion 3D printing on the performance of the printed solid dosage forms', Journal of Materials Chemistry B, 12 (1)., pp. 131 - 144. doi: 10.1039/d3tb01868g.

DOI BRAD record
NEW Drenos, F., Emmett, P., Blakemore, A., Nordström, T., Hurtig, T., Jarvelin, M. and Dovey, T. (2023). Associations of adolescents’ diet and meal patterns with school performance in the Northern Finland Birth Cohort 1986: A Mendelian randomisation study. Appetite, 190, 107036, pp. 1 - 10. doi: 10.1016/j.appet.2023.107036.

DOI BRAD record
NEW Schmidt, A., Joshi, R., Gordillo-Marañón, M., ..., Drenos, F. et al. (2023). Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes. Schmidt, A.F., et al. (2023). 'Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes' in Communications Medicine., Vol. 3 (9)., pp.1 - 10. https://doi.org/10.1038/s43856-022-00234-0.

DOI BRAD record
NEW Box, C., Pennington, C., Hare, S., Porter, S., Edwards, D., Eccles, S., Crompton, M. and Harvey, A. (2023). Brk/PTK6 and Involucrin Expression May Predict Breast Cancer Cell Responses to Vitamin D. International Journal of Molecular Sciences, 2023, 24, 10757, pp. 1 - 14. doi: 10.3390/ijms241310757.

DOI BRAD record
NEW Stamatiou, K., Chmielewska, A., Ohta, S., Earnshaw, W. and Vagnarelli, P. (2023). CCDC86 is a novel Ki-67-interacting protein important for cell division. Journal of Cell Science, 136 (2), pp. 1 - 13. doi: 10.1242/jcs.260391.

DOI BRAD record
NEW Zhang, B. (2023). Computational fluid dynamics analysis of the fluid environment of 3D printed tissue scaffolds within a perfusion bioreactor: the effect of pore shape. Procedia Structural Integrity, 49, pp. 3 - 9. doi: 10.1016/j.prostr.2023.10.002.

DOI BRAD record
NEW Ragusa, D. and Vagnarelli, P. (2023). Contribution of histone variants to aneuploidy: a cancer perspective. Ragusa, D. and Vagnarelli, P. (2023) ‘Contribution of histone variants to aneuploidy: a cancer perspective’, Frontiers in Genetics, 14, 1290903, pp. 1 - 17. doi: 10.3389/fgene.2023.1290903.

DOI BRAD record
NEW Freke, G., Martins, T., Davies, R., ..., Hernandez, V. et al. (2023). De-Suppression of Mesenchymal Cell Identities and Variable Phenotypic Outcomes Associated with Knockout of Bbs1. Cells, 12 (22), 2662, pp. 1 - 21. doi: 10.3390/cells12222662.

DOI BRAD record
NEW Mustafov, D., Karteris, E. and Braoudaki, M. (2023). Deciphering the Role of microRNA Mediated Regulation of Coronin 1C in Glioblastoma Development and Metastasis. Non-coding RNA, 9 (1), pp. 1 - 18. doi: 10.3390/ncrna901000.4.

DOI BRAD record
NEW Ramzi, N., Auvinen, J., Veijola, J., ..., Drenos, F. et al. (2023). Depression mediates the relationship between alexithymia and obesity in the Northern Finland Birth Cohort 1966 (NFBC1966). Journal of Affective Disorders, 331, pp. 1 - 7. doi: 10.1016/j.jad.2023.03.026.

DOI BRAD record
NEW Alizzi, Z., Roxburgh, P., Cartwright, D., ..., Karteris, E. et al. (2023). Description of a Retrospective Cohort of Epithelial Ovarian Cancer Patients with Brain Metastases: Evaluation of the Role of PARP Inhibitors in this Setting. Journal of Clinical Medicine, 12 (7), 2497, pp. 1 - 13. doi: 10.3390/jcm12072497.

DOI BRAD record
NEW Alizzi, Z., Gogbashian, A., Karteris, E. and Hall, M. (2023). Development of a dual energy CT based model to assess response to treatment in patients with high grade serous ovarian cancer: a pilot cohort study. Alizzi, Z. et al. (2023) ‘Development of a dual energy CT based model to assess response to treatment in patients with high grade serous ovarian cancer: a pilot cohort study’, Cancer Imaging, 23 (62), pp.1 - 11. doi: 10.1186/s40644-023-00579-2.

DOI BRAD record
NEW James, E., Sagi-Kiss, V., Bennett, M., Mycielska, M., Karen-Ng, L., Roberts, T., Matta, S., Dokal, I., Bundy, J. and Parkinson, E. (2023). Dyskeratosis Congenita links telomere attrition to age-related systemic energetics. The Journals of Gerontology: Series A, 78 (5), pp. 780 - 789. doi: 10.1093/gerona/glad018.

DOI BRAD record
NEW D’Avino, P., Vagnarelli, P. and Wilde, A. (2023). Editorial: Mechanics and regulation of mitotic exit and cytokinesis. Frontiers in Cell and Developmental Biology, 11, 1191987, pp. 1 - 3. doi: 10.3389/fcell.2023.1191987.

DOI BRAD record
NEW Brown, M., Leon, A., Kedzierska, K., ..., Lewis, A. et al. (2023). Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis. EMBO Molecular Medicine, 15 (10), e17094, pp. 1 - 18. doi: 10.15252/emmm.202217094.

DOI BRAD record
NEW Pairo-Castineira, E., Rawlik, K., Bretherick, A., ..., Harvey, A., Lewis, A. et al. (2023). GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19. Nature, 617 (7962), pp. 764 - 768. doi: 10.1038/s41586-023-06034-3.

DOI BRAD record
NEW Ahmed, A., Amin, H., Drenos, F., Sattar, N. and Yaghootkar, H. (2023). Genetic Evidence Strongly Supports Managing Weight and Blood Pressure in Addition to Glycemic Control in Preventing Vascular Complications in People With Type 2 Diabetes. Diabetes Care, 2023, 46 (10), pp. 1783 - 1791. doi: 10.2337/dc23-0855.

DOI BRAD record
NEW Dijkhuis, L., Johns, A., Ragusa, D., van den Brink, S. and Pina, C. (2023). Haematopoietic development and HSC formation in vitro: promise and limitations of gastruloid models. Dijkhuis, L. et al. (2024) ‘M-FISH evaluation of chromosome aberrations to examine for historical exposure to ionising radiation due to participation at British nuclear test sites’ in Journal of Radiological Protection, 7 (4), pp. 439 - 454. doi: 10.1042/ETLS20230091.

DOI BRAD record
NEW Alizzi, Z., Saravi, S., Khalique, S., Mcdonald, T., Karteris, E. and Hall, M. (2023). Identification of RAD51 foci in cancer-associated circulating cells of patients with high-grade serous ovarian cancer: Association with treatment outcomes. International Journal of Gynecological Cancer, 33 (9), pp. 1427 - 1433. doi: 10.1136/ijgc-2023-004483.

DOI BRAD record
NEW Jones, M., Moffatt, F., Harvey, A. and Ryan, J. (2023). Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis. Cochrane Database of Systematic Reviews, 2023 (7), Art. No.: CD013610, pp. 1 - 53. doi: 10.1002/14651858.CD013610.pub2.

DOI BRAD record
NEW Cullen, S., Mackay, R., Mohagheghi, A. and Du, X. (2023). Low-Cost Smartphone Photogrammetry Accurately Digitises Positive Socket and Limb Casts. Prosthesis, 5 (4), pp. 1382 - 1392. doi: 10.3390/prosthesis5040095.

DOI BRAD record
NEW Buttery, S., Banya, W., Boyd, E., ..., Lewis, A. et al. (2023). Lung volume reduction surgery versus endobronchial valves: a randomised controlled trial. European Respiratory Journal, 61 (4), 2202063, pp. 1 - 14. doi: 10.1183/13993003.02063-2022.

DOI BRAD record
NEW Zeka, K., Taylor, A., Samarista, R., ..., Pina, C. et al. (2023). MAT2A inhibition in AML unveils therapeutic potential of combining DNA demethylating agents with UPR targeting. bioRxiv, [preprint], 2023.06.05.543499, pp. 1 - 20. doi: 10.1101/2023.06.05.543499.

DOI BRAD record
NEW Eastwood, M., Marc, S., Gao, X., ..., Karteris, E. et al. (2023). Malignant Mesothelioma subtyping via sampling driven multiple instance prediction on tissue image and cell morphology data. Artificial Intelligence in Medicine, 143, 102628, pp. 1 - 7. doi: 10.1016/j.artmed.2023.102628.

DOI BRAD record
NEW Ragusa, D., Dijkhuis, L., Pina, C. and Tosi, S. (2023). Mechanisms associated with t(7;12) acute myeloid leukaemia: from genetics to potential treatment targets. Bioscience Reports, 43 (1), BSR20220489, pp. 1 - 17. doi: 10.1042/bsr20220489.

DOI BRAD record
NEW Eastwood, M., Sailem, H., Tudor, S., ..., Karteris, E. et al. (2023). MesoGraph: Automatic Profiling of Malignant Mesothelioma Subtypes from Histological Images. arXiv:2302.12653v1 [cs.CV], pp. 1 - 20. doi: 10.48550/arXiv.2302.12653.

DOI BRAD record
NEW Eastwood, M., Sailem, H., Marc, S., ..., Karteris, E. et al. (2023). MesoGraph: Automatic profiling of mesothelioma subtypes from histological images. Cell Reports Medicine, 2023, 4 (10), 101226, pp. 1 - 16. doi: 10.1016/j.xcrm.2023.101226.

DOI BRAD record
NEW Mo, Z., Wang, Q., Shi, H., Zhang, B. and Sui, W. (2023). Pointhuman: Reconstructing Clothed Human From Point Cloud Of Parametric Model. Computing and Informatics, 42 (2), pp. 457 - 479. doi: 10.31577/cai_2023_2_457.

DOI BRAD record
NEW McAuley, H., Evans, R., Brightling, C., ..., Harvey, A. et al. (2023). Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study. eClinicalMedicine, 57, 101896, pp. 1 - x. doi: 10.1016/j.eclinm.2023.101896.

DOI BRAD record
NEW Kaci, F., Lepore, A., Papa, S. and Bubici, C. (2023). Screening Kinase-Dependent Phosphorylation of Key Metabolic Reprogramming Regulators.

BRAD record
NEW Musvosvi, M., Huang, H., Wang, C., ..., Roberts, T. et al. (2023). T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection. Nature Medicine, 29 (1), pp. 258 - 269. doi: 10.1038/s41591-022-02110-9.

DOI BRAD record
NEW Mokbel, K., Kodresko, A., Ghazal, H., Mokbel, R., Trembley, J. and Jouhara, H. (2023). The Evolving Role of Cryosurgery in Breast Cancer Management: A Comprehensive Review. Cancers, 15 (17), 4272, pp. 1 - 13. doi: 10.3390/cancers15174272.

DOI BRAD record
NEW Grillo, L., Russell, A., Shannon, H., Cullinan, P. and Lewis, A. (2023). The Physiotherapy Assessment of Breathing Pattern Disorder: A Qualitative evaluation. BMJ Open Respiratory Research, 10 (1), e001395, pp.1-9. doi: 10.1136/bmjresp-2022-001395.

DOI BRAD record
NEW Knight, M., Pels, N., Yadav, S., Elhelu, O., Parn, S., Rinaldi, G., Grigoriadis, D., Mann, V., Brindley, P. and Bridger, J. (2023). The human pathogen, Schistosoma mansoni, lacks the cognate sequence for human telomerase reverse transcriptase (hTERT) and relies on the snail host, Biomphalaria glabrata homologous enzyme for its intra-molluscan development. Research Square preprint, pp. 1 - xx. doi: 10.21203/rs.3.rs-3069723/v1.

DOI BRAD record
NEW Jerin, S., Harvey, A. and Lewis, A. (2023). Therapeutic Potential of Protein Tyrosine Kinase 6 in Colorectal Cancer. Cancers, 15 (14), 3703, pp. 1 - 17. doi: 10.3390/cancers15143703.

DOI BRAD record
NEW Kerslake, R., Belay, B., Panfilov, S., Hall, M., Kyrou, I., Randeva, H., Hyttinen, J., Karteris, E. and Sisu, C. (2023). Transcriptional Landscape of 3D vs. 2D Ovarian Cancer Cell Models. Cancers, 15 (13), 3350, pp. 1 - 21. doi: 10.3390/cancers15133350.

DOI BRAD record
NEW Steinmann, J., Lewis, A., Ellmers, T., Jones, M., MacBean, V. and Kal, E. (2023). Validating the Breathing Vigilance Questionnaire for use in Dysfunctional Breathing. European Respiratory Journal, 61 (6), 2300031 (23 pp.). doi: 10.1183/13993003.00031-2023.

DOI BRAD record

2022

NEW Kerslake, R., Belay, B., Panfilov, S., Hall, M., Kyrou, I., Randeva, H., Hyttinen, J., Karteris, E. and Sisu, C. (2022). A Meta-analysis of 2D vs. 3D Ovarian Cancer Cellular Models. bioRxiv, (preprint), pp. 1 - 31. doi: 10.1101/2022.12.05.519144.

DOI BRAD record
NEW Abdelhalim, M., Patel, A., Moquet, J., Saha, P., Smith, A., Badie, C., Anderson, R., Ainsbury, E. and Modarai, B. (2022). A higher incidence of chromosomal aberrations in operators performing a large volume of endovascular procedures. Abdelhalim, M.A., Patel, A., Moquet, J., Saha, P., Smith, A., Badie, C., Anderson, R., Ainsbury, E.A., and Modarai, B. (2022). 'A higher incidence of chromosomal aberrations in operators performing a large volume of endovascular procedures', Circulation., 145 (24), pp. 1808-1810. doi: 10.1161/CIRCULATIONAHA.121.058139.

DOI BRAD record
NEW Houghton-Gisby, J., Kerslake, R., Karteris, E., Mokbel, K. and Harvey, A. (2022). ACBD3 bioinformatic analysis and protein expression in breast cancer cells. International Journal of Molecular Sciences. 23 (16), 8881, pp. 1 - 22. doi: 10.3390/ijms23168881.

DOI BRAD record
NEW Bridger, J., Torres Pereira, R., Pina, C., Tosi, S. and Lewis, A. (2022). Alterations to Genome Organisation in Stem Cells, their Differentiation and Associated Diseases. in: Kloc, M. and Kubiak, J.Z. (eds.) Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine (Results and Problems in Cell Differentiation, vol. 70). Cham, Switzerland: Springer Nature, pp. 71 - 102. doi: 10.1007/978-3-031-06573-6_3.

DOI BRAD record
NEW Philip, K., Owles, H., McVey, S., ..., Lewis, A. et al. (2022). An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms following COVID-19: a parallel-group, single-blind, randomised controlled trial. The Lancet Respiratory Medicine, 10 (9), pp. 851 - 862. doi: 10.1016/S2213-2600(22)00125-4.

DOI BRAD record
NEW Suleman, S., Fawaz, S., Roberts, T., Bigger, B., Ellison, S. and Themis, M. (2022). An optimised protocol to generate high titre lentiviral vectors by extended HEK293T culture following transient transfection and suspension culture. Human Gene Therapy, 33 (23-24), pp. A103 - A103. doi: 10.1089/hum.2022.29225.abstracts

BRAD record
NEW Shabir, K., Gharanei, S., Orton, S., Patel, V., Chauhan, P., Karteris, E., Randeva, H., Brown, J. and Kyrou, I. (2022). Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway. Shabir, K. et al. (2023) 'Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway', International Journal of Molecular Sciences, 24 (1), 227, pp. 1 - 16. doi: 10.3390/ijms24010227.

DOI BRAD record
NEW Zagkos, L., Dib, M., Pinto, R., ..., Drenos, F. et al. (2022). Associations of genetically predicted fatty acid levels across the phenome: A mendelian randomisation study. PLoS Medicine, 19 (12), e1004141, pp. 1 - 20. doi: 10.1371/journal.pmed.1004141.

DOI BRAD record
NEW Abascal, F., Acosta, R., Addleman, N., ..., Sisu, C. et al. (2022). Author Correction: Perspectives on ENCODE (Nature, (2020), 583, 7818, (693-698), 10.1038/s41586-020-2449-8). Nature, 605 (7909), E4, pp.1 - 1. doi: 10.1038/s41586-021-04213-8.

DOI BRAD record
NEW Kortenkamp, A., Martin, O., Ermler, S., Baig, A. and Scholze, M. (2022). Bisphenol A and declining semen quality: A systematic review to support the derivation of a reference dose for mixture risk assessments. Journal of Hygiene and Environmental Health, 241, 113942, pp. 1 - 12. doi: 10.1016/j.ijheh.2022.113942.

DOI BRAD record
NEW Nsamba, J., Eroju, P., Drenos, F. and Mathews, E. (2022). Body Composition Characteristics of Type 1 Diabetes Children and Adolescents: A Hospital-Based Case-Control Study in Uganda. Children, 9 (11), 1720, pp. 1 - 12. doi: 10.3390/children9111720.

DOI BRAD record
NEW Burmi, R., Box, G., Wazir, U., Hussain, H., Davies, J., William, C., Eccles, S., Jiang, W., Mokbel, K. and Harvey, A. (2022). Breast Tumour Kinase (Brk/PTK6) Contributes to Breast Tumour Xenograft Growth and Modulates Chemotherapeutic Responses In Vitro. Genes, 13, 402, pp. 1 - 13.. doi: 10.3390/genes13030402.

DOI BRAD record
NEW Rake, C., Gilham, C., Scholze, M., Bukasa, L., Stephens, J., Simpson, J., Peto, J. and Anderson, R. (2022). British nuclear test veteran family trios for the study of genetic risk. Journal of Radiological Protection, 42, 021528, pp. 1-11. doi: 10.1088/1361-6498/ac6e10.

DOI BRAD record
NEW Kortenkamp, A., Scholze, M., Ermler, S., Priskorn, L., Jørgensen, N., Andersson, A. and Frederiksen, H. (2022). Combined exposures to bisphenols, polychlorinated dioxins, paracetamol, and phthalates as drivers of deteriorating semen quality. Environment International, 165, 107322, pp. 1 - 14. doi: 10.1016/j.envint.2022.107322.

DOI BRAD record
NEW Ermler, S. and Kortenkamp, A. (2022). Declining semen quality and polybrominated diphenyl ethers (PBDEs): Review of the literature to support the derivation of a reference dose for a mixture risk assessment. Ermler, S. and Kortenkamp, A. (2022) ‘Declining semen quality and polybrominated diphenyl ethers (PBDEs): Review of the literature to support the derivation of a reference dose for a mixture risk assessment’, International Journal of Hygiene and Environmental Health, 242, 113953, pp. 1-10. doi: 10.1016/j.ijheh.2022.113953.

DOI BRAD record
NEW Perera, M., Suleman, S., Al Haque, S., ..., Payne, A., Themis, M. et al. (2022). Development of a human-based platform to assess adeno-associated viral vector genotoxicity. Human Gene Therapy, 33 (23-24), pp. A39 - A40. doi: 10.1089/hum.2022.29225.abstracts.

DOI BRAD record
NEW Zhang, B., Teoh, X., Yan, J., Gleadall, A., Belton, P., Bibb, R. and Qi, S. (2022). Development of combi-pills using the coupling of semi-solid syringe extrusion 3D printing with fused deposition modelling. Zhang, B. et al. (2022) ‘Development of combi-pills using the coupling of semi-solid syringe extrusion 3D printing with fused deposition modelling’, International Journal of Pharmaceutics, 625, 122140, pp. 1 - 14, doi: 10.1016/j.ijpharm.2022.122140.

DOI BRAD record
NEW Karkia, R., Wali, S., Payne, A., Karteris, E. and Chatterjee, J. (2022). Diagnostic Accuracy of Liquid Biomarkers for the Non-Invasive Diagnosis of Endometrial Cancer: A Systematic Review and Meta-Analysis. Cancers, 2022, 14 (19), pp. 1 - 28. doi: 10.3390/cancers14194666.

DOI BRAD record
NEW Filipe, A., Chudasama, D., Kerslake, R., Jeyaneethi, J., Anikin, V., Kyrou, I., Randeva, H., Sisu, C., Hall, M. and Karteris, E. (2022). Differential Expression of RAD51AP1 in Ovarian Cancer: Effects of siRNA In Vitro. Journal of Personalized Medicine, 12 (2), 201, pp. 1-13. doi: 10.3390/jpm12020201.

DOI BRAD record
NEW Kerslake, R., Sisu, C., Panfilov, S., Hall, M., Khan, N., Jeyaneethi, J., Randeva, H., Kyrou, I. and Karteris, E. (2022). Differential Regulation of Genes by the Glucogenic Hormone Asprosin in Ovarian Cancer. Journal of Clinical Medicine, 11 (19), 5942, pp. 1 - 18. doi: 10.3390/jcm11195942.

DOI BRAD record
NEW Ragusa, D., Suen, C., Torregrosa Cortes, G., ..., Pina, C. et al. (2022). Dissecting infant leukemia developmental origins with a hemogenic gastruloid model. bioRxiv, [preprint]. 2022.10.07.511362, pp. 1 - 43. doi: 10.1101/2022.10.07.511362.

DOI BRAD record
NEW Zhang, B., Mi, Y., Zhang, L., Zhang, Y., Li, M., Zhai, Q. and Li, M. (2022). Dynamic Community Detection Method of a Social Network Based on Node Embedding Representation. Mathematics, 10 (24), 4738, pp. 1 - 22. doi: 10.3390/math10244738.

DOI BRAD record
NEW Kerslake, R., Panfilov, S., Mustafa, N., Hall, M., Kyrou, I., Randeva, H., Karteris, E. and Godfrey, R. (2022). Elevated Circulating Lactate Levels and Widespread Expression of Its Cognate Receptor, Hydroxycarboxylic Acid Receptor 1 (HCAR1), in Ovarian Cancer. Journal of Clinical Medicine, 12 (1), 217, pp. 1 - 13. doi: 10.3390/jcm12010217.

DOI BRAD record
NEW Ragusa, D., Cicirò, Y., Federico, C., Saccone, S., Bruno, F., Saeedi, R., Sisu, C., Pina, C., Sala, A. and Tosi, S. (2022). Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles. Oncogenesis, 11 (1), 50, pp. 1-7. doi: 10.1038/s41389-022-00426-2.

DOI BRAD record
NEW Frankish, A., Carbonell-Sala, S., Diekhans, M., ..., Sisu, C. et al. (2022). GENCODE: reference annotation for the human and mouse genomes in 2023. Frankish, A. et al. (2023) 'GENCODE: reference annotation for the human and mouse genomes in 2023', Nucleic acids research, 51 (D1), pp. D942 - D949. doi: 10.1093/nar/gkac1071.

DOI BRAD record
NEW Suleman, S., Payne, A., Bowden, J., ..., Themis, M. et al. (2022). HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival. Gene Therapy, 29 (12), pp. 720 - 729 (10). doi: 10.1038/s41434-022-00335-4.

DOI BRAD record
NEW Suleman, S., Payne, A., Bowden, J., ..., Themis, M. et al. (2022). HIV-1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival. Human Gene Therapy, 33 (23-24), pp. A48 - A48. doi: 10.1089/hum.2022.29225.abstracts.

DOI BRAD record
NEW Ragusa, D., Suen, C., Torregrosa, G., ..., Pina, C. et al. (2022). Haemogenic Gastruloids Recapitulate Developmental Haematopoiesis and Provide an Ontogeny-Relevant Context to Dissect the Origins of Infant Leukemia. Blood, 140 (Supplement 1), pp. 1684 - 1685. doi: 10.1182/blood-2022-169733.

DOI BRAD record
NEW Payoe, S., Safa, A., Payne, A. and Stenbeck, G. (2022). Identification of differentially expressed immune receptor genes in osteosarcoma. Bone Reports, 16 (Supplement), 101489, pp. 78 - 78. doi: 10.1016/j.bonr.2022.101489.

DOI BRAD record
NEW Zahra, A., Kerslake, R., Kyrou, I., Randeva, H., Sisu, C. and Karteris, E. (2022). Impact of environmentally relevant concentrations of Bisphenol A (BPA) on the gene expression profile in an in vitro model of the normal human ovary. Zahra, A., Kerslake, R., Kyrou, I., Randeva, H.S., Sisu, C. and Karteris. E. (2022) ‘Impact of Environmentally Relevant Concentrations of Bisphenol A (BPA) on the Gene Expression Profile in an In Vitro Model of the Normal Human Ovary’, International Journal of Molecular Sciences, 23(10), 5334, pp. 1 - 14. doi:10.3390/ijms23105334.

DOI BRAD record
NEW Zahra, A., Hall, M., Chatterjee, J., Sisu, C. and Karteris, E. (2022). In Silico Study to predict the structural and functional consequences of SNPs on biomarkers of ovarian cancer (OC) and BPA exposure-associated OC. Zahra, A., Hall, M, Chatterjee, J., Sisu, C. and Karteris, E. (2022) ‘In Silico Study to Predict the Structural and Functional Consequences of SNPs on Biomarkers of Ovarian Cancer (OC) and BPA Exposure-Associated OC’, International Journal of Molecular Sciences, 23 (3), 1725, p. 1-14. doi: 10.3390/ijms23031725.

DOI BRAD record
NEW Nsamba, J., Nabirye, G., Hense, S., Drenos, F. and Mathews, E. (2022). Lived Experiences of Newly Diagnosed Type 1 Diabetes Mellitus Children and Adolescents in Uganda. Journal of Multidisciplinary Healthcare, 15, pp. 2647 - 2665. doi: 10.2147/jmdh.s389265.

DOI BRAD record
NEW Wang, R., Lei, T., Cui, R., Zhang, B., Meng, H. and Nandi, A. (2022). Medical Image Segmentation Using Deep Learning: A Survey. IET Image Processing, 16 (5), pp. 1243 - 1267. doi: 10.1049/ipr2.12419.

DOI BRAD record
NEW Amin, H., Kaewsri, P., Yiorkas, A., Cooke, H., Blakemore, A. and Drenos, F. (2022). Mendelian randomisation analyses of UK Biobank and published data suggest that increased adiposity lowers risk of breast and prostate cancer. Scientific Reports, 12 (1), 909, pp. 1-10. doi: 10.1038/s41598-021-04401-6.

DOI BRAD record
NEW Gomes, S., Baltazar, F., Silva, E. and Preto, A. (2022). Microbiota-Derived Short-Chain Fatty Acids: New Road in Colorectal Cancer Therapy. Gomes S. et. al.(2022) 'Microbiota-Derived Short-Chain Fatty Acids: New Road in Colorectal Cancer Therapy' in Pharmaceutics, 14 (11), 2359, pp. 1 - 22. doi: 10.3390/pharmaceutics14112359.

DOI BRAD record
NEW Gharanei, S., Ramanjaneya, M., Patel, A., Patel, V., Shabir, K., Auld, C., Karteris, E., Kyrou, I. and Randeva, H. (2022). NUCB2/Nesfatin-1 Reduces Obesogenic Diet Induced Inflammation in Mice Subcutaneous White Adipose Tissue. Nutrients, 2022, 14 (7), 1409, pp. 1-17. doi: 10.3390/nu14071409.

DOI BRAD record
NEW Meier, S., Seddon, J., Maasdorp, E., ..., Roberts, T. et al. (2022). Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis. PLoS ONE, 17 (12), e0278295, pp. 1 - 24. doi: 10.1371/journal.pone.0278295.

DOI BRAD record
NEW Moorhouse, A., Scholze, M., Sylvius, N., Gilham, C., Rake, C., Peto, J., Anderson, R. and Dubrova, Y. (2022). No evidence of increased mutations in the germline of a group of British nuclear test veterans. Scientific Reports, 12, 10830, pp. 1-8. doi: 10.1038/s41598-022-14999-w.

DOI BRAD record
NEW Steele, E., Gorczynski, R., Lindley, R., ..., Slijepcevic, P. et al. (2022). Overview SARS-CoV-2 Pandemic as January-February 2022: Likely Cometary Origin, Global Spread, Prospects for Future Vaccine Efficacy. Infectious Diseases and Therapeutics, 3 (1), pp. 260 - 275. doi: 10.31038/IDT.2022311.

DOI BRAD record
NEW Ragusa, D., Tosi, S. and Sisu, C. (2022). Pan-Cancer Analysis Identifies MNX1 and Associated Antisense Transcripts as Biomarkers for Cancer. Cells, 11 (22), 3577, pp. 1 - 21. doi: 10.3390/cells11223577.

DOI BRAD record
NEW Grillo, L., Lewis, A., Shannon, H. and Russell, A. (2022). Physiotherapists’ opinions of the physiotherapy assessment of Breathing Pattern Dysfunction: a qualitative study. Thorax, 77 (Suppl. 1), pp. A13 - A13. doi: 10.1136/thorax-2022-BTSabstracts.20.

DOI BRAD record
NEW Lewis, A., Kal, E., Nolan, C., Cave, P., Grillo, L., Conway, J. and Jones, M. (2022). Pilot study of physiotherapist-led versus music therapist-led breathing control exercises for young adults living with breathing pattern disorder: a randomised controlled trial protocol. BMJ Open Respiratory Research, 9, e001414, pp. 1 - 7. doi: 10.1136/bmjresp-2022-001414.

DOI BRAD record
NEW Lewis, A., Conway, J., Middleton, J., Startup, C. and Wyatt, J. (2022). Playing the Harmonica with Chronic Obstructive Pulmonary Disease. A qualitative study. Chronic Respiratory Disease, 19 (1), pp. 1-9. doi: 10.1177/14799731221083315.

DOI BRAD record
NEW Kerslake, R., Randeva, H., Jonigk, D., Werlein, C., Robertus, J., Katopodis, P., Jasker, P., Spandidos, D., Kyrou, I. and Karteris, E. (2022). Protein expression of transmembrane protease serine 4 in the gastrointestinal tract and in healthy, cancer, and SARS‑CoV‑2 infected lungs. Molecular medicine reports, 25 (4), 138, pp. 1 - 6. doi: 10.3892/mmr.2022.12654.

DOI BRAD record
NEW Huguet, F., Gokhan, E., Foster, H., Amin, H. and Vagnarelli, P. (2022). Repo-Man/PP1 SUMOylation mediates binding to lamin A and Serine 22 dephosphorylation. Open Biology, 12 (4), 220017, pp. 1-12. doi: 10.1098/rsob.220017.

DOI BRAD record
NEW Valls, P. and Esposito, A. (2022). Signalling dynamics, cell decisions, and homeostatic control in health and disease. Current Opinion in Cell Biology, 75, 102066, pp. 1 - 9. doi: 10.1016/j.ceb.2022.01.011.

DOI BRAD record
NEW Ermler, S. and Kortenkamp, A. (2022). Systematic review of associations of polychlorinated biphenyl (PCB) exposure with declining semen quality in support of the derivation of reference doses for mixture risk assessments. Ermler, S., Kortenkamp, A. (2022) Systematic review of associations of polychlorinated biphenyl (PCB) exposure with declining semen quality in support of the derivation of reference doses for mixture risk assessments. Environ Health Vol. 21. https://doi.org/10.1186/s12940-022-00904-5

DOI BRAD record
NEW Teoh, X., Zhang, B., Belton, P., Chan, S. and Qi, S. (2022). The Effects of Solid Particle Containing Inks on the Printing Quality of Porous Pharmaceutical Structures Fabricated by 3D Semi-Solid Extrusion Printing. Qi, S. et al. (2022) The Effects of Solid Particle Containing Inks on the Printing Quality of Porous Pharmaceutical Structures Fabricated by 3D Semi-Solid Extrusion Printing. Pharm Res., vol. 39 (6), pp. 1267 - 1279. https://doi.org/10.1007/s11095-022-03299-7

DOI BRAD record
NEW Buhigas, C., Warren, A., Leung, W., ..., Haberland, V. et al. (2022). The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates. Molecular Cancer, 21 (1), 183, pp. 1 - 13. doi: 10.1186/s12943-022-01644-3.

DOI BRAD record
NEW Anas, S., Kyrou, I., Rand-Weaver, M. and Karteris, E. (2022). The effect of online and in-person team-based learning (TBL) on undergraduate endocrinology teaching during COVID-19 pandemic. BMC Medical Education, 22 (1), 120, pp. 1-9. doi: 10.1186/s12909-022-03173-5.

DOI BRAD record
NEW Steinmann, J., Lewis, A., Ellmers, T., Jones, M., MacBean, V. and Kal, E. (2022). The validity and reliability of the Breathing Vigilance Questionnaire (Breathe-VQ). Thorax, 77 (Suppl 1), pp. A12 - A13. doi: 10.1136/thorax-2022-BTSabstracts.19.

DOI BRAD record
NEW Gupta, S., Dovey, O., Domingues, A., ..., Hernandez, V., Pina, C. et al. (2022). Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis. Science Advances, 8, eabn4886, pp. 1 - 15. doi: 10.1126/sciadv.abn4886.

DOI BRAD record
NEW Jiang, X., Anasanti, M., Drenos, F., Blakemore, A. and Pazoki, R. (2022). Urinary Sodium Excretion Enhances the Effect of Alcohol on Blood Pressure. Jiang, X., Anasanti, M.D., Drenos, F., Blakemore, A.J. and Pazoki, R. (2022) ''Urinary Sodium Excretion Enhances the Effect of Alcohol on Blood Pressure, Healthcare, 10 (7), 1296, pp. 1 - 13. doi: 10.3390/healthcare10071296.

DOI BRAD record
NEW Steinmann, J., Lewis, A., Ellmers, T., Jones, M., MacBean, V. and Kal, E. (2022). Validating the Breathing Vigilance Questionnaire for use in Dysfunctional Breathing. medRxiv, (preprint), pp. 1 - 24. doi:10.1101/2022.07.11.22277501.

DOI BRAD record
NEW Lewis, A. and Osadnik, C. (2022). changing practice by changing pressures: A role for oscillating positive expiratory pressure in chronic obstructive pulmonary disease. Thorax, 78 (2), pp. 113 - 115. doi: 10.1136/thorax-2022-219451.

DOI BRAD record
NEW Panraksa, P., Zhang, B., Rachtanapun, P., Jantanasakulwong, K., Qi, S. and Jantrawut, P. (2022). ‘Tablet-in-Syringe’: A Novel Dosing Mechanism for Dysphagic Patients Containing Fast-Disintegrating Tablets Fabricated Using Semisolid Extrusion 3D Printing. Pharmaceutics, 14 (2), 443, pp. 1-18. doi: 10.3390/pharmaceutics14020443.

DOI BRAD record

2021

NEW Osório, L., Silva, E. and Mackay, R. (2021). A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip (OOAC) Systems. Osório, L. A., Silva, E. and Mackay, R. E. (2021) ‘A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip (OOAC) Systems’, Bioengineering, 8(8), 113, p. 1-.31 doi: 10.3390/bioengineering8080113.

DOI BRAD record
NEW Kerslake, R., Hall, M., Vagnarelli, P., Jeyaneethi, J., Randeva, H., Pados, G., Kyrou, I. and Karteris, E. (2021). A pancancer overview of FBN1, asprosin and its cognate receptor OR4M1 with detailed expression profiling in ovarian cancer. Kerslake, R., Hall, M., Vagnarelli, P., Jeyaneethi, J., Randeva, H.S., Pados, G. ... Karteris, E. (2021). A pancancer overview of FBN1, asprosin and its cognate receptor OR4M1 with detailed expression profiling in ovarian cancer. Oncology Letters, 22, 650. doi: 10.3892/ol.2021.12911

DOI BRAD record
NEW Scott, D., Francis-Newton, N., Marsh, M., ..., Esposito, A. et al. (2021). A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death. Cell Chemical Biology, 28 (6), pp. 835 - 847 (+ e1 - e5). doi: 10.1016/j.chembiol.2021.02.006.

DOI BRAD record
NEW Zagkos, L., Drenos, F., Emmett, P., Blakemore, A., Nordstrom, T., Hurtig, T., Jarvelin, M. and Dovey, T. (2021). Adolescents’ dietary habits and meal patterns influence school performance in the Northern Finland Birth Cohort 1986: mendelian randomisation study. Zagkos L, Drenos F, Emmett P, Blakemore AI, Nordstrom T, Hurtig T, Jarvelin MR, Dovey TM. Adolescents’ dietary habits and meal patterns influence school performance in the Northern Finland Birth Cohort 1986: mendelian randomisation study. bioRxiv. 2021 Jan 1. doi: 10.1101/2021.04.30.442179

DOI BRAD record
NEW Philip, K., Lewis, A., Buttery, S., McCabe, C., Fancourt, D., Orton, C., Polkey, M. and Hopkinson, N. (2021). Aerosol transmission of SARS-CoV-2: inhalation as well as exhalation matters. American Journal of Respiratory and Critical Care Medicine, 203 (8), pp. 1041 - 1042. doi: 10.1164/rccm.202012-4445LE.

DOI BRAD record
NEW Roa-Díaz, Z., Asllanaj, E., Amin, H., ..., Drenos, F. et al. (2021). Age at natural menopause and blood pressure traits: Mendelian randomization study. Roa-Díaz, Z.M., Asllanaj, E., Amin, H.A., Rojas, L.Z., Nano, J., Ikram, M.A., Drenos, F., Franco, O.H., Pazoki R., Marques-Vidal, P., Voortman, T. and Muka, T. (2021) ‘Age at Natural Menopause and Blood Pressure Traits: Mendelian Randomization Study’, Journal of Clinical Medicine, 10 (19), 4299, pp. 1-13. doi:10.3390/jcm10194299.

DOI BRAD record
NEW Themis, M., Al-Haque, S., Wang, W. et al. (2021). Application of InGetox to assess the genotoxicity of LV and AAV vectors. Human Gene Therapy, 32 (19-20), pp. A136 - A136. doi: 10.1089/hum.2021.29180.abstracts.

BRAD record
NEW Vagnarelli, P. (2021). Back to the new beginning: Mitotic exit in space and time. Seminars in Cell & Developmental Biology, 117, pp. 140 - 148. doi: 10.1016/j.semcdb.2021.03.010

DOI BRAD record
NEW Trinh, A. and Esposito, A. (2021). Biochemical resolving power of fluorescence lifetime imaging: untangling the roles of the instrument response function and photon-statistics. Biomedical Optics Express, 12 (7), 428070, pp. 3775 - 3788. doi: 10.1364/BOE.428070.

DOI BRAD record
NEW Katopodis, P., Kerslake, R., Davies, J., ..., Karteris, E. et al. (2021). COVID‑19 and SARS‑CoV‑2 host cell entry mediators: Expression profiling of TMRSS4 in health and disease. International Journal of Molecular Medicine, 47 (4), 64, pp. 1-7. doi: 10.3892/ijmm.2021.4897.

DOI BRAD record
NEW Houlden, A. and Mackay, R. (2021). Can microfluidics be used to create a more realistic in vitro model of the vaginal ectocervix to better understand bacterial vaginosis?. Houlden, A. and Mackay, R. (2022) 'Can microfluidics be used to create a more realistic in vitro model of the vaginal ectocervix to better understand bacterial vaginosis?' Sexually Transmitted Infections, 98, pp. 74 - 74 (1). doi: 10.1136/sextrans-2021-055225.

DOI BRAD record
NEW Roupakia, E., Chavdoula, E., Karpathiou, G., ..., Karteris, E. et al. (2021). Canonical NF-κB promotes lung epithelial cell tumour growth by downregulating the metastasis suppressor CD82 and enhancing epithelial-to-mesenchymal cell transition. Roupakia, E., Chavdoula, E., Karpathiou, G., Vatsellas, G., Chatzopoulos, D., Mela, A., Gillette, J.M., Kriegsmann, K., Kriegsmann, M., Batistatou, A., Goussia, A., Marcu, K.B., Karteris, E., Klinakis, A. and Kolettas, E. (2021) ‘Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition’, Cancers. MDPI AG, 13 (17), 4302, pp. 1-26. doi: 10.3390/cancers13174302.

DOI BRAD record
NEW Schmidt, A., Hunt, N., Gordillo-Marañón, M., ..., Drenos, F. et al. (2021). Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease. Nature Communications, 12, 5640, pp. 1-10. doi: 10.1038/s41467-021-25703-3.

DOI BRAD record
NEW Federico, C., Bruno, F., Ragusa, D., Clements, C., Brancato, D., Henry, M., Bridger, J., Tosi, S. and Saccone, S. (2021). Chromosomal Rearrangements and Altered Nuclear Organization: Recent Mechanistic Models in Cancer. Federico, C., Bruno, F., Ragusa, D., Clements, C. S., Brancato, D., Henry, M. P., Bridger, J. M., Tosi, S. and Saccone, S. (2021) ‘Chromosomal Rearrangements and Altered Nuclear Organization: Recent Mechanistic Models in Cancer’, Cancers, 13 (22), 5860, pp. 1-13. doi: 10.3390/cancers13225860.

DOI BRAD record
NEW Stamatiou, K. and Vagnarelli, P. (2021). Chromosome Clustering in mitosis by the nuclear protein Ki-67. Stamatiou, K. and Vagnarelli, P. (2021) 'Chromosome Clustering in mitosis by the nuclear protein Ki-67;, Biochemical Society Transactions, 49 (6), pp. 2767 - 2776 (10). doi: 10.1042/BST20210717.

DOI BRAD record
NEW Katopodis, P., Anikin, V., Kishore, U., Carter, T., Hall, M., Asadi, N., Polychronis, A. and Karteris, E. (2021). Circulating tumour cells and circulating cell-free DNA in lung cancer patients: A comparison between Thoracotomy and Video-Assisted Thoracoscopic Surgery. BMJ Open Respiratory Research 8, e000917, pp. 1 - 10. doi: 10.1136/bmjresp-2021-000917.

DOI BRAD record
NEW Esposito, A. (2021). Cooperation of partially transformed clones: An invisible force behind the early stages of carcinogenesis. Royal Society Open Science, 8 (2), 201532, pp. 1 - 12. doi: 10.1098/rsos.201532.

DOI BRAD record
NEW Lewis, A., Pavitt, M., Buttery, S., Fernandez, B., Mikus-Lelinska, M., Banya, W., Feelisch, M., Polkey, M. and Hopkinson, N. (2021). Dietary nitrate supplementation to enhance exercise capacity in hypoxic COPD: EDEN-OX a double-blind, placebo-controlled, randomised crossover study. Pavitt, M.J. et al. (2022) 'Dietary nitrate supplementation to enhance exercise capacity in hypoxic COPD: EDEN-OX, a double-blind, placebo-controlled, randomised cross-over study', Thorax, 77 (10), pp. 968 - 975 (+ 15 suppl. pp.). doi: 10.1136/thoraxjnl-2021-217147

DOI BRAD record
NEW Zhang, B., Nguyen, A., Narayan, R. and Huang, J. (2021). Direct ink writing of vancomycin-loaded polycaprolactone/ polyethylene oxide/ hydroxyapatite 3D scaffolds. Journal of the American Ceramic Society, 105 (3), pp. 1821 - 1840. doi: 10.1111/jace.18048.

DOI BRAD record
NEW Bastiani, I., McMahon, S., Turner, P., Redmond, K., McGarry, C., Cole, A., O'Sullivan, J., Prise, K., Ainsbury, L. and Anderson, R. (2021). Dose estimation after a mixed field exposure: Radium-223 and intensity modulated radiotherapy. Bastiani, I. et al. (2022) 'Dose estimation after a mixed field exposure: Radium-223 and intensity modulated radiotherapy', Nuclear Medicine and Biology, 106-107, pp. 10 - 20. doi: 10.1016/j.nucmedbio.2021.12.002.

DOI BRAD record
NEW Zhang, B., Nasereddin, J., McDonagh, T., von Zeppelin, D., Gleadall, A., Alqahtani, F., Bibb, R., Belton, P. and Qi, S. (2021). Effects of porosity on drug release kinetics of swellable and erodible porous pharmaceutical solid dosage forms fabricated by hot melt droplet deposition 3D printing. Zhang, B. et al. (2021) ‘Effects of porosity on drug release kinetics of swellable and erodible porous pharmaceutical solid dosage forms fabricated by hot melt droplet deposition 3D printing’, International Journal of Pharmaceutics. 604, 120626, pp.1-11. https://doi.org/10.1016/j.ijpharm.2021.120626.

DOI BRAD record
NEW Garner, J., Biddiscombe, M., Meah, S., Lewis, A., Buttery, S., Hopkinson, N., Kemp, S., Usmani, O., Shah, P. and Verbanck, S. (2021). Endobronchial Valve Lung Volume Reduction and Small Airways Function. Garner J, Biddiscombe MF, Meah S, Lewis A, Buttery SC, Hopkinson NS, Kemp SV, Usmani OS, Shah PL, Verbanck S. Endobronchial Valve Lung Volume Reduction and Small Airways Function. American Journal of Respiratory and Critical Care Medicine. doi: 10.1164/rccm.202010-3939le

DOI BRAD record
NEW Yin, S., Wang, Y., Zhang, B., Qu, Y., Liu, Y., Dai, S., Zhang, Y., Wang, Y. and Bi, J. (2021). Engineered human heavy-chain ferritin with half-life extension and tumor targeting by PAS and RGDK peptide functionalization. Yin, S. et al. (2021) ‘Engineered Human Heavy-Chain Ferritin with Half-Life Extension and Tumor Targeting by PAS and RGDK Peptide Functionalization’, Pharmaceutics, 13 (4), 521, pp. 1 - 16. doi: 10.3390/pharmaceutics13040521.

DOI BRAD record
NEW Liu, Y., Elsworth, B., Erola, P., Haberland, V., Hemani, G., Lyon, M., Zheng, J., Lloyd, O., Vabistsevits, M. and Gaunt, T. (2021). Erratum: EpiGraphDB: A database and data mining platform for health data science (Bioinformatics (2020) DOI: 10.1093/bioinformatics/btaa961). Bioinformatics, 37 (2), pp. 288 - 288. doi: 10.1093/bioinformatics/btab104.

DOI BRAD record
NEW Beymer, D., Rajan, D., Coy, A., ..., Karteris, E. et al. (2021). Erratum: On the role of artificial intelligence in medical imaging of COVID-19 (Patterns (2021) 2(6), (S2666389921000957), (10.1016/j.patter.2021.100269)). Patterns, 2021, 2 (8), 100330, pp. 1 - 1. doi: 10.1016/j.patter.2021.100330.

DOI BRAD record
NEW Collett, G., Young, W., Martin, W. and Anderson, R. (2021). Exposure Worry: The Psychological Impact of Perceived Ionizing Radiation Exposure in British Nuclear Test Veterans. Collett, G., Young, W.R., Martin, W. and Anderson, R.M. (2021) ‘Exposure Worry: The Psychological Impact of Perceived Ionizing Radiation Exposure in British Nuclear Test Veterans’, International Journal of Environmental Research and Public Health, 18 (22), 12188, pp. 1-xx. doi: 10.3390/ijerph182212188.

DOI BRAD record
NEW Gulino, G., Bruno, F., Sturiale, V., Brancato, D., Ragusa, D., Tosi, S., Saccone, S. and Federico, C. (2021). From FISH to Hi-C: the chromatin architecture of the chromosomal region 7q36.3, frequently rearranged in leukemic cells, is evolutionary conserved. Gulino, G. M., Bruno, F., Sturiale, V., Brancato, D., Ragusa, D., Tosi, S., Saccone, S. and Federico, C. (2021) ‘From FISH to Hi-C: The Chromatin Architecture of the Chromosomal Region 7q36.3, Frequently Rearranged in Leukemic Cells, Is Evolutionary Conserved’, International Journal of Molecular Sciences, 22(5), 2338, pp. 1-16. doi: 10.3390/ijms22052338.

DOI BRAD record
NEW Frankish, A., Diekhans, M., Jungreis, I., ..., Sisu, C. et al. (2021). GENCODE 2021. Nucleic acids research, 2021, 49 (D1), pp. D916 - D923 doi: 10.1093/nar/gkaa1087

DOI BRAD record
NEW Brooke-Hollidge, A., Conway, J. and Lewis, A. (2021). Gender Differences in Non-Cystic Fibrosis Bronchiectasis Severity and Bacterial Load: The Potential Role of Hormones. Brooke-Hollidge, A., Conway, J. and Lewis, A. (2021) ‘Gender differences in non-cystic fibrosis bronchiectasis severity and bacterial load: the potential role of hormones’, Therapeutic Advances in Respiratory Disease, 15, pp. 1-9. doi: 10.1177/17534666211035311.

DOI BRAD record
NEW Katopodis, P., Randeva, H., Spandidos, D., Saravi, S., Kyrou, I. and Karteris, E. (2021). Host cell entry mediators implicated in the cellular tropism of SARS‑CoV‑2, the pathophysiology of COVID‑19 and the identification of microRNAs that can modulate the expression of these mediators (Review). Katopodis, P., Randeva, H.S., Spandidos, D.A., Saravi, S., Kyrou, I. and Karteris, E. (2022) 'Host cell entry mediators implicated in the cellular tropism of SARS‑CoV‑2, the pathophysiology of COVID‑19 and the identification of microRNAs that can modulate the expression of these mediators (Review)', International Journal of Molecular Medicine, 49 (2), 20, pp. 1-12. doi: 10.3892/ijmm.2021.5075.

DOI BRAD record
NEW Zahra, A., Dong, Q., Hall, M., Jeyaneethi, J., Silva, E., Karteris, E. and Sisu, C. (2021). Identification of Potential Bisphenol A (BPA) Exposure Biomarkers in Ovarian Cancer. Zahra, A., Dong, Q., Hall, M., Jeyaneethi, J., Silva, E., Karteris, E. and Sisu, C. (2021) ‘Identification of Potential Bisphenol A (BPA) Exposure Biomarkers in Ovarian Cancer’, Journal of Clinical Medicine, 10(9), 1979, pp. 1-20. doi: 10.3390/jcm10091979.

DOI BRAD record
NEW Mehta, I., Riyahi, K., Torres Pereira, R., Meaburn, K., Figgitt, M., Kill, I., Eskiw, C. and Bridger, J. (2021). Interphase Chromosomes in Replicative Senescence: chromosome positioning as a senescence biomarker and the lack of nuclear motor-driven chromosome repositioning in senescent cells. Frontiers in Cell and Developmental Biology, 9, 640200, pp. 1-18. doi: 10.3389/fcell.2021.640200.

DOI BRAD record
NEW Arede, L., Foerner, E., Wind, S., ..., Pina, C. et al. (2021). KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia. Arede, L., Foerner, E., Sterre Wind, S., Kulkarni, R., Domingues, A.F., Giotopoulos, G., Kleinwächter,S., Mollenhauer-Starkl, M., Davison, H., Chandru, A., Asby, R., Samarista, R., Gupta, S., Forte, D., Curti, A., Scheer, E., James, B., Huntly, P., Tora, L. and Pina, C. (2022) 'KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia', Blood Advances, 6 (1), pp. 165 - 180 (16). doi: 10.1182/bloodadvances.2020002842.

DOI BRAD record
NEW Suleman, S., Payne, A., Bowden, J., ..., Themis, M. et al. (2021). Lentivirus tethering to the genome is associated with transcription factor binding sites that favour virus survival. Human Gene Therapy, 32 (19-20), pp. A138 - A139. doi: 10.1089/hum.2021.29180.abstracts.

DOI BRAD record
NEW Tsakaneli, A., Carregari, V., Morini, M., ..., Makarov, E. et al. (2021). MYC regulates metabolism through vesicular transfer of glycolytic kinases. Open Biology, 11(12), 210276, pp. 1-15. doi: 10.1098/rsob.210276.

DOI BRAD record
NEW Sirunyan, A., Tumasyan, A., Adam, W., ..., Tosi, S. et al. (2021). Measurements of pp -> ZZ production cross sections and constraints on anomalous triple gauge couplings at root s=13 TeV. Sirunyan, A.M., Tumasyan, A., Adam, W. et al. Measurements of pp→ZZ production cross sections and constraints on anomalous triple gauge couplings at s√=13TeV. Eur. Phys. J. C 81, 200 (2021). https://doi.org/10.1140/epjc/s10052-020-08817-8

DOI BRAD record
NEW Yin, S., Liu, Y., Dai, S., Zhang, B., Qu, Y., Zhang, Y., Choe, W. and Bi, J. (2021). Mechanism Study of Thermally Induced Anti-Tumor Drug Loading to Engineered Human Heavy-Chain Ferritin Nanocages Aided by Computational Analysis. Yin, S. et al. (2021) ‘Mechanism Study of Thermally Induced Anti-Tumor Drug Loading to Engineered Human Heavy-Chain Ferritin Nanocages Aided by Computational Analysis’, Biosensors, 11 (11), 444, pp. 1 - 17. doi: 10.3390/bios11110444.

DOI BRAD record
NEW Barravecchia, I., De Cesari, C., Forcato, M., ..., Bridger, J. et al. (2021). Microgravity and space radiation inhibit autophagy in human capillary endothelial cells, through either opposite or synergistic effects on specific molecular pathways. Barravecchia, I. et al. (2022) 'Microgravity and space radiation inhibit autophagy in human capillary endothelial cells, through either opposite or synergistic effects on specific molecular pathways', Cellular and Molecular Life Sciences, 79, 28, pp. 1 - 29. doi: 10.1007/s00018-021-04025-z.

DOI BRAD record
NEW Lau, D., McLean, M., Priest, A., ..., Lewis, A. et al. (2021). Multiparametric MRI of early tumor response to immune checkpoint blockade in metastatic melanoma. Journal for ImmunoTherapy of Cancer, 9 (9), e003125, pp. 1 - 14. doi: 10.1136/jitc-2021-003125.

DOI BRAD record
NEW O’Cathail, S., Wu, C., Thomas, R., Hawkins, M., Maughan, T. and Lewis, A. (2021). NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch. O’Cathail, S. M., Wu, C.-H., Thomas, R., Hawkins, M. A., Maughan, T. S. and Lewis, A. (2021) ‘NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch’, Antioxidants, 10 (9), 1380, pp. 1-14. doi: 10.3390/antiox10091380.

DOI BRAD record
NEW Zhang, B., Gleadall, A., Belton, P., Mcdonagh, T., Bibb, R. and Qi, S. (2021). New insights into the effects of porosity, pore length, pore shape and pore alignment on drug release from extrusionbased additive manufactured pharmaceuticals. Additive Manufacturing, 2021, 46, 102196, pp. 1 - 18. doi: 10.1016/j.addma.2021.102196.

DOI BRAD record
NEW Amin, H., Cordell, H., Martin-Ruiz, C., Robinson, L., Kirkwood, T., Blakemore, A. and Drenos, F. (2021). No Evidence That Genetic Variation at the Klotho Locus Is Associated With Longevity in Caucasians from the Newcastle 85+ Study and the UK Biobank. Amin, H.A. et al. (2022) 'No Evidence That Genetic Variation at the Klotho Locus Is Associated With Longevity in Caucasians from the Newcastle 85+ Study and the UK Biobank', The Journals of Gerontology: Series A, 77 (3), pp. 457 - 461. doi: 10.1093/gerona/glab361.

DOI BRAD record
NEW Amin, H. and Drenos, F. (2021). No evidence that vitamin D is able to prevent or affect severity of COVID-19 in individuals with European ancestry: A Mendelian randomisation study of open data. BMJ Nutrition, Prevention & Health, 4 (1), pp. 42 - 48 (7) + suppl. doi: 10.1136/bmjnph-2020-000151.

DOI BRAD record
NEW Sales Gil, R., Kommer, D., de Castro, I., Amin, H., Vinciotti, V., Sisu, C. and Vagnarelli, P. (2021). Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression. EMBO reports, 22 (11), e52061, pp. 1-18. doi: 10.15252/embr.202052061.

DOI BRAD record
NEW Kyrou, I., Randeva, H., Spandidos, D. and Karteris, E. (2021). Not only ACE2—the quest for additional host cell mediators of SARS-CoV-2 infection: Neuropilin-1 (NRP1) as a novel SARS-CoV-2 host cell entry mediator implicated in COVID-19. Signal Transduction and Targeted Therapy, 6 (1), 21, pp. 1-3. doi: 10.1038/s41392-020-00460-9.

DOI BRAD record
NEW Born, J., Beymer, D., Rajan, D., ..., Karteris, E. et al. (2021). On the role of artificial intelligence in medical imaging of COVID-19. Patterns, 2 (6), pp. 1 - 18. doi: 10.1016/j.patter.2021.100269.

DOI BRAD record
NEW Erady, C., Boxall, A., Puntambekar, S., ..., Pina, C. et al. (2021). Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions. npj Genomic Medicine, 6 (1), pp. 1-17. doi: 10.1038/s41525-020-00167-4.

DOI BRAD record
NEW Azizi Machekposhti, S., Zhang, B., Sachan, R., Vanderwal, L., Stafslien, S. and Narayan, R. (2021). Patterned surfaces with the controllable drug doses using inkjet printing. Journal of Materials Research, 36 (19), pp. 3865 - 3876. doi: 10.1557/s43578-021-00135-3.

DOI BRAD record
NEW Lepore, A., Choy, P., Lee, N., ..., Bubici, C. et al. (2021). Phosphorylation and stabilization of PIN1 by JNK promote intrahepatic cholangiocarcinoma growth. Hepatology, 74 (5), pp. 2561 - 2579. doi: 10.1002/hep.31983.

DOI BRAD record
NEW Philip, K., Lewis, A., Buttery, S., McCabe, C., Manivannan, B., Fancourt, D., Orton, C., Polkey, M. and Hopkinson, N. (2021). Physiological demands of singing for lung health compared with treadmill walking. BMJ Open Respiratory Research, 8 (1), e000959, pp. 1-7. doi: 10.1136/bmjresp-2021-000959.

DOI BRAD record
NEW Lewis, A., Conway, J., Middleton, J., Startup, C. and Wyatt, J. (2021). Playing the Harmonica with Chronic Obstructive Pulmonary Disease. A qualitative study. medRxiv 2021.08.01.21261448, pp. 1-22. doi: 10.1101/2021.08.01.21261448.

DOI BRAD record
NEW Saravi, S., Alizzi, Z., Tosi, S., Hall, M. and Karteris, E. (2021). Preclinical Studies on the Effect of Rucaparib in Ovarian Cancer: Impact of Brca2 Status. Saravi, S., Alizzi, Z., Tosi, S., Hall, M. and Karteris, E. (2021) ‘Preclinical Studies on the Effect of Rucaparib in Ovarian Cancer: Impact of BRCA2 Status’, Cells, 10(9), 2434, pp. 1-13. doi: 10.3390/cells10092434.

DOI BRAD record
NEW Suleman, S., Schrubaji, K., Filippou, C., Ignatova, S., Hewitson, P., Huddleston, J., Karda, R., Waddington, S. and Themis, M. (2021). Rapid and inexpensive purification of adenovirus vectors using an optimised aqueous two-phase technology. Suleman, S., Schrubaji, K., Filippou, C., Ignatova, S., Hewitson, P., Huddleston, J., Karda, R., Waddington, S.N. and Themis, M. (2022) 'Rapid and inexpensive purification of adenovirus vectors using an optimised aqueous two-phase technology', Journal of Virological Methods, 299, 114305, pp. 1-9. doi: 10.1016/j.jviromet.2021.114305.

DOI BRAD record
NEW Slijepcevic, P. and Wickramasinghe, C. (2021). Reconfiguring SETI in the microbial context: Panspermia as a solution to Fermi's paradox. BioSystems, 206, 104441, pp. 1 - 8. doi: 10.1016/j.biosystems.2021.104441.

DOI BRAD record
NEW Kassotis, C., Hoffman, K., Völker, J., ..., Ermler, S. et al. (2021). Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study. Toxicology, 461, 152900, pp. 1-13. doi: 10.1016/j.tox.2021.152900.

DOI BRAD record
NEW Papa, S., Bubici, C. and Syn, W. (2021). STARD1: a new rising StAR in cholesterol-mediated hepatocarcinogenesis. Papa S, Bubici C, Syn WK. STARD1: a new rising StAR in cholesterol-mediated hepatocarcinogenesis. HepatoBiliary Surg Nutr 2021;10(6):910-912. doi: 10.21037/ hbsn-21-374

DOI BRAD record
NEW Slijepcevic, P. (2021). Serial Endosymbiosis Theory: From biology to astronomy and back to the origin of life. BioSystems, 202, 104353, pp. 1 - 9. doi: 10.1016/j.biosystems.2021.104353.

DOI BRAD record
NEW Haas, K., Fries, M., Venkitaraman, A. and Esposito, A. (2021). Single-Cell Biochemical Multiplexing by Multidimensional Phasor Demixing and Spectral Fluorescence Lifetime Imaging Microscopy. Frontiers in Physics, 9, 637123, pp. 1 - 14. doi: 10.3389/fphy.2021.637123.

DOI BRAD record
NEW Hutt, S., Mihaies, D., Karteris, E., Michael, A., Payne, A. and Chatterjee, J. (2021). Statistical Meta-Analysis of Risk Factors for Endometrial Cancer and Development of a Risk Prediction Model Using an Artificial Neural Network Algorithm. Cancers, 13 (15), 3689, pp. 1 - 22. doi: 10.3390/cancers13153689.

DOI BRAD record
NEW Drenos, F. (2021). Systems epidemiology of metabolomics measures reveals new relationships between lipoproteins and other small molecules. Drenos, F. (2022) 'Systems epidemiology of metabolomics measures reveals new relationships between lipoproteins and other small molecules', Metabolomics 18, 1, pp. 1-11. doi: 10.1007/s11306-021-01856-6.

DOI BRAD record
NEW Costa, J., Mackay, R., de Aguiar Greca, S., Corti, A., Silva, E., Karteris, E. and Ahluwalia, A. (2021). The Role of the 3Rs for Understanding and Modeling the Human Placenta. Costa, J., Mackay, R., de Aguiar Greca, S.-C., Corti, A., Silva, E., Karteris, E. and Ahluwalia, A. (2021) ‘The Role of the 3Rs for Understanding and Modeling the Human Placenta’, Journal of Clinical Medicine, 10 (15), 10(15), 3444, pP. 1-xx. doi: 10.3390/jcm10153444.

DOI BRAD record
NEW Lewis, A., Knight, E., Bland, M., Middleton, J., Mitchell, E., McCrum, K., Conway, J. and Bevan-Smith, E. (2021). The feasibility of an online platform delivery of pulmonary rehabilitation for individuals with chronic respiratory disease. BMJ Open Respiratory Research, 8, e000880, pp. 1-8. doi:10.1136/bmjresp-2021-000880.

DOI BRAD record
NEW Lewis, A., Philip, EJ, P, Lound, A., Cave, P., Russell, J. and Hopkinson, N. (2021). The physiology of singing and implications for 'Singing for Lung Health' as a therapy for individuals with Chronic Obstructive Pulmonary Disease. BMJ Open Respiratory Research 8, e000996, pp. 1 - 7. doi: 10.1136/bmjresp-2021-000996.

DOI BRAD record
NEW Cullen, S., Mackay, R., Mohagheghi, A. and Du, X. (2021). The use of smartphone photogrammetry to digitise transtibial sockets: Optimisation of method and quantitative evaluation of suitability. Cullen, S. et al. (2021) ‘The Use of Smartphone Photogrammetry to Digitise Transtibial Sockets: Optimisation of Method and Quantitative Evaluation of Suitability’, Sensors, 21 (24), 8405, pp. 1 - 16. doi: 10.3390/s21248405.

DOI BRAD record
NEW Gupta, S., Dovey, O., Domingues, A., ..., Hernandez, V., Pina, C. et al. (2021). Transcriptional variability accelerates pre-leukemia by cell diversification and 2 perturbation of protein synthesis. Gupta, S., Dovey, O.M., Domingues, A.F., Cyran, O.W., Cash, C.M., Giotopoulos, G., Rak, J., Cooper, J., Gozdecka, M., Asby, R.J., Al-Jabery, N., Hernandez, V., Prabakaran, S., Huntly, B.J., Vassiliou, G.S. and Pina C. (2021) biorXiv preprint, 2021.10.18.464824, pp. 1-15. doi: 10.1101/2021.10.18.464824.

DOI BRAD record
NEW Gordillo-Marañón, M., Zwierzyna, M., Charoen, P., ..., Drenos, F. et al. (2021). Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics. Nature Communications, 12, 6120, pp. 1-12. doi: 10.1038/s41467-021-25731-z.

DOI BRAD record

2020

NEW Arede, L. and Pina, C. (2020). Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and development. Arede, L. and Pina, C. (2021) 'Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and development', Experimental hematology, 93, pp. 25-37. doi: 10.1016/j.exphem.2020.10.003.

DOI BRAD record
NEW Camilleri, M., Zhang, X., Norris, M., ..., Harvey, A. et al. (2020). Covid-19 ICU Remote-Learning Course (CIRLC): Rapid ICU remote training for frontline health professionals during the COVID-19 pandemic in the UK. Camilleri, M. et al. (2022) ‘Covid-19 ICU remote-learning course (CIRLC): Rapid ICU remote training for frontline health professionals during the COVID-19 pandemic in the UK’, Journal of the Intensive Care Society, 23 (2), pp. 183 - 190. doi: 10.1177/1751143720972630.

DOI BRAD record
NEW Kerslake, R., Hall, M., Randeva, H., Spandidos, D., Chatha, K., Kyrou, I. and Karteris, E. (2020). Co‑expression of peripheral olfactory receptors with SARS‑CoV‑2 infection mediators: Potential implications beyond loss of smell as a COVID‑19 symptom. International Journal of Molecular Medicine doi: 10.3892/ijmm.2020.4646

DOI BRAD record
NEW Philip, K., Lewis, A., Williams, S., Buttery, S., Polkey, M., Man, W., Fancourt, D. and Hopkinson, N. (2020). Dance for people with chronic respiratory disease: A qualitative study. Philip KEJ, Lewis A, Williams S, et alDance for people with chronic respiratory disease: a qualitative studyBMJ Open 2020;10:e038719. doi: 10.1136/bmjopen-2020-038719

DOI BRAD record
NEW Martin, O., Ermler, S., Baynes, A. and McPhie, J. (2020). Data collection in support of the Endocrine Disruption (ED) assessment for non-target vertebrates. EFSA supporting publication, 17 (5), EN-1849, pp. 1 - 131. doi: 10.2903/sp.efsa.2020.EN-1849.

DOI BRAD record
NEW Zhang, B., Chung, S., Barker, S., Craig, D., Narayan, R. and Huang, J. (2020). Direct ink writing of polycaprolactone / polyethylene oxide based 3D constructs. Zhang, B. et al. (2021) 'Direct ink writing of polycaprolactone / polyethylene oxide based 3D constructs', Progress in Natural Science: Materials International, 31 (2), pp. 180 - 191. doi: 10.1016/j.pnsc.2020.10.001.

DOI BRAD record
NEW Surendran, P., Feofanova, E., Lahrouchi, N., ..., Drenos, F. et al. (2020). Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nature Genetics 52, pp. 1314 - 1332. doi: 10.1038/s41588-020-00713-x.

DOI BRAD record
NEW Li, J., Dong, W., Zhang, B. and Zhou, X. (2020). Effects of creep recovery on the fracture properties of concrete. Theoretical and Applied Fracture Mechanics, 109, 102694, pp. 1 - 9. doi: 10.1016/j.tafmec.2020.102694.

DOI BRAD record
NEW Klonos, E., Katopodis, P., Karteris, E., Papanikolaou, E., Tarlatzis, B. and Pados, G. (2020). Endometrial changes in estrogen and progesterone receptor expression during implantation in an oocyte donation program. Klonos, E., Katopodis, P., Karteris, E., Papanikolaou, E., Tarlatzis, B., & Pados, G. (2020). Endometrial changes in estrogen and progesterone receptor expression during implantation in an oocyte donation program. Experimental and Therapeutic Medicine, 20, 178. doi: 10.3892/etm.2020.9308

DOI BRAD record
NEW Liu, Y., Elsworth, B., Erola, P., Haberland, V., Hemani, G., Lyon, M., Zheng, J., Lloyd, O., Vabistsevits, M. and Gaunt, T. (2020). EpiGraphDB: A database and data mining platform for health data science. Liu, Y. et al. (2021) 'EpiGraphDB: A database and data mining platform for health data science', Bioinformatics, 37 (9), pp. 1304 - 1311. doi: 10.1093/bioinformatics/btaa961.

DOI BRAD record
NEW The ENCODE Project Consortium, Moore, J., Weng, Z. and Sisu, C. (2020). Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature,, 583, pp. 699 - 710. doi: 10.1038/s41586-020-2493-4.

DOI BRAD record
NEW Saravi, S., Katsuta, E., Jeyaneethi, J., Amin, H., Kaspar, M., Takabe, K., Pados, G., Drenos, F. and Hall, M. (2020). H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival. Saravi, S., Katsuta, E., Jeyaneethi, J., Amin, H. A., Kaspar, M., Takabe, K., Pados, G., Drenos, F., Hall, M. and Karteris, E. (2020) ‘H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival’, Journal of Clinical Medicine. MDPI AG, 9(9), 2844, pp. 1-14. doi: 10.3390/jcm9092844.

DOI BRAD record
NEW Sales Gil, R. and Vagnarelli, P. (2020). How HP1 post-translational modifications regulate heterochromatin formation and maintenance. Cells, 9 (6), 1460, pp. 1-13. doi: 10.3390/cells9061460.

DOI BRAD record
NEW Murugaiah, V., Agostinis, C., Varghese, P., ..., Roberts, T. et al. (2020). Hyaluronic Acid Present in the Tumor Microenvironment Can Negate the Pro-apototic Effect of a Recombinant Fragment of Human Surfactant Protein D on Breast Cancer Cells. Frontiers in Immunology, 11, 1171, pp. 1-17. doi: 10.3389/fimmu.2020.01171.

DOI BRAD record
NEW Carter, T., Jeyaneethi, J., Kumar, J., Karteris, E., Glynne-Jones, R. and Hall, M. (2020). Identification of Cancer-Associated Circulating Cells in Anal Cancer Patients. Carter, T.J.; Jeyaneethi, J.; Kumar, J.; Karteris, E.; Glynne-Jones, R.; Hall, M. Identification of Cancer-Associated Circulating Cells in Anal Cancer Patients. Cancers 2020, 12, 2229. doi: 10.3390/cancers12082229

DOI BRAD record
NEW Katopodis, P., Dong, Q., Halai, H., Fratila, C., Polychronis, A., Anikin, V., Sisu, C. and Karteris, E. (2020). In silico and in vitro analysis of lncRNA XIST reveals a panel of possible lung cancer regulators and a five-gene diagnostic signature. Katopodis, P., Dong, Q., Halai, H., Fratila, C. I., Polychronis, A., Anikin, V., Sisu, C. and Karteris, E. (2020) ‘In Silico and In Vitro Analysis of lncRNA XIST Reveals a Panel of Possible Lung Cancer Regulators and a Five-Gene Diagnostic Signature’, Cancers, 12 (12), 3499 , pp. 1 - 16. doi: 10.3390/cancers12123499.

DOI BRAD record
NEW Axson, E., Lewis, A., Potts, J., Pang, M., Dickinson, S., Vioix, H. and Quint, J. (2020). Inhaled therapies for chronic obstructive pulmonary disease: a systematic review and meta-analysis. BMJ Open 10 (9), e036455, pp. 1 - 11. doi: 10.1136/bmjopen-2019-036455.

DOI BRAD record
NEW Jones, M., Moffatt, F., Harvey, A. and Ryan, J. (2020). Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis. Cochrane Database of Systematic Reviews, 2020 (5), Article no. CD013610, pp. 1 - 11. doi: 10.1002/14651858.CD013610.

DOI BRAD record
NEW de Aguiar Greca, S., Kyrou, I., Pink, R., Randeva, H., Grammatopoulos, D., Silva, E. and Karteris, E. (2020). Involvement of the Endocrine-Disrupting Chemical Bisphenol A (BPA) in Human Placentation. de Aguiar Greca, S.-C.; Kyrou, I.; Pink, R.; Randeva, H.; Grammatopoulos, D.; Silva, E.; Karteris, E. Involvement of the Endocrine-Disrupting Chemical Bisphenol A (BPA) in Human Placentation. J. Clin. Med. 2020, 9, 405. doi: 10.3390/jcm9020405

DOI BRAD record
NEW Zahra, A., Sisu, C., Silva, E., De Aguiar Greca, S., Randeva, H., Chatha, K., Kyrou, I. and Karteris, E. (2020). Is there a link between bisphenol A (BPA), a key endocrine disruptor, and the risk for SARS-CoV-2 infection and severe COVID-19?. Zahra, A., Sisu, C., Silva, E., De Aguiar Greca, S.-C., Randeva, H. S., Chatha, K., Kyrou, I. and Karteris, E. (2020) ‘Is There a Link between Bisphenol A (BPA), a Key Endocrine Disruptor, and the Risk for SARS-CoV-2 Infection and Severe COVID-19?’, Journal of Clinical Medicine. MDPI AG, 9(10), 3296, pp. 1-15. doi: 10.3390/jcm9103296.

DOI BRAD record
NEW Bomer, M., Perez Salamo, I., Florance, H., Salmon, D., Dudenhoffer, J., Finch, P., Cinar, A., Smirnoff, N., Harvey, A. and Devoto, A. (2020). Jasmonates induce Arabidopsis bioactivities selectively inhibiting the growth of breast cancer cells through CDC6 and mTOR. New Phytologist, in press, pp. 1-15. doi:10.1111/nph.17031.

DOI BRAD record
NEW Barr, J., Chudasama, D., Rice, A., Karteris, E. and Anikin, V. (2020). Lack of association between screencell-detected circulating tumour cells and long-term survival of patients undergoing surgery for non-small cell lung cancer: A pilot clinical study. Barr, J., Chudasama, D., Rice, A., Karteris, E., & Anikin, V. (2020). Lack of association between Screencell-detected circulating tumour cells and long‑term survival of patients undergoing surgery for non‑small cell lung cancer: A pilot clinical study. Molecular and Clinical Oncology, 12, 191-195. https://doi.org/10.3892/mco.2020.1981

DOI BRAD record
NEW Domingues, A., Kulkarni, R., Giotopoulos, G., ..., Pina, C. et al. (2020). Loss of Kat2a Enhances Transcriptional Noise and depletes Acute Myeloid Leukaemia Stem-like Cells. Elife, 9, e51754, pp. 1-29. doi: 10.7554/eLife.51754.

DOI BRAD record
NEW Buttery, S., Lewis, A., Kemp, S., Banya, W., Quint, J., Steiner, M. and Hopkinson, N. (2020). Lung volume reduction eligibility in patients with COPD completing pulmonary rehabilitation: results from the UK National Asthma and COPD Audit Programme. BMJ Open, 10 (11), e040942, pp. 1-5. doi: 10.1136/bmjopen-2020-040942.

DOI BRAD record
NEW Corner, E., Zhang, X., Van Willigan, Z., ..., Harvey, A. et al. (2020). Mixed methods evaluation of the impact of the COVID-19 ICU remote-learning rehabilitation course for frontline health professionals during the COVID-19 pandemic in the UK. Corner, E.J. et al. (2022) ‘Mixed methods evaluation of the impact of the COVID-19 ICU remote-learning rehabilitation course for frontline health professionals during the COVID-19 pandemic in the UK’, Journal of the Intensive Care Society, 23 (4), pp. 485 - 491. doi: 10.1177/17511437211043043.

DOI BRAD record
NEW Philip, K., Lewis, A., Jeffery, E. et al. (2020). Moving singing for lung health online in response to COVID-19: experience from a randomised controlled trial. BMJ Open Respiratory Research, 2020, 7 (1), e000737, pp. 1 - 11. doi:10.1136/bmjresp-2020-000737.

DOI BRAD record
NEW O'Cathail, S., Wu, C., Lewis, A., Holmes, C., Hawkins, M. and Maughan, T. (2020). NRF2 metagene signature is a novel prognostic biomarker in colorectal cancer. Cancer Genetics, 248-249 pp. 1 - 10. doi: 10.1016/j.cancergen.2020.08.006.

DOI BRAD record
NEW Slijepcevic, P. (2020). Natural Intelligence and Anthropic Reasoning. . Biosemiotics, 13, pp. 285 - 307. doi: 10.1007/s12304-020-09388-7.

DOI BRAD record
NEW Davies, J., Randeva, H., Chatha, K., Hall, M., Spandidos, D., Karteris, E. and Kyrou, I. (2020). Neuropilin‑1 as a new potential SARS‑CoV‑2 infection mediator implicated in the neurologic features and central nervous system involvement of COVID‑19. Molecular Medicine Reports, 22 (5), pp. 4221 - 4226. doi: 10.3892/mmr.2020.11510.

DOI BRAD record
NEW Pavitt, M., Tanner, R., Lewis, A. et al. (2020). Oral nitrate supplementation to enhance pulmonary rehabilitation in COPD: ON-EPIC a multi-centre, double-blind, placebo-controlled, randomised parallel group study. Thorax

BRAD record
NEW Katopodis, P., Anikin, V., Randeva, H., Spandidos, D., Chatha, K., Kyrou, I. and Karteris, E. (2020). Pan‑cancer analysis of transmembrane protease serine 2 and cathepsin L that mediate cellular SARS‑CoV‑2 infection leading to COVID-19. International Journal of Oncology, 2020, 57(2): 533 - 539 doi: 10.3892/ijo.2020.5071

DOI BRAD record
NEW Snyder, M., Gingeras, T., Abascal, F., ..., Sisu, C. et al. (2020). Perspectives on ENCODE. Nature, 2020, 583 (7818), pp. 693 - 698. doi:10.1038/s41586-020-2449-8.

DOI BRAD record
NEW Zheng, J., Haberland, V., Baird, D. et al. (2020). Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases. Nature Genetics, 52 (10), pp. 1122 - 1131. doi: 10.1038/s41588-020-0682-6.

DOI BRAD record
NEW Kyrou, I., Karteris, E., Robbins, T., Chatha, K., Drenos, F. and Randeva, H. (2020). Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic. Kyrou, I., Karteris, E., Robbins, T. et al. Polycystic ovary syndrome (PCOS) and COVID-19: an overlooked female patient population at potentially higher risk during the COVID-19 pandemic. BMC Med 18, 220 (2020). https://doi.org/10.1186/s12916-020-01697-5

DOI BRAD record
NEW Lewis, A., Nolan, C., Man, W., Kon, S. and Conway, J. (2020). Prognostication in COPD using physical function measures: Let's walk before we run away with conclusions. Respiratory Medicine, 167, 105942, pp. 1 - 2. doi 10.1016/j.rmed.2020.105942. doi: 10.1016/j.rmed.2020.105942

DOI BRAD record
NEW Balogh, E., Chandler, J., Varga, M., ..., Tomita, K. et al. (2020). Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. Eszter Balogh, Jennifer C. Chandler, Máté Varga, Mona Tahoun, Dóra K. Menyhárd, Gusztáv Schay, Tomas Goncalves, Renáta Hamar, Regina Légrádi, Ákos Szekeres, Olivier Gribouval, Robert Kleta, Horia Stanescu, Detlef Bockenhauer, Andrea Kerti, Hywel Williams, Veronica Kinsler, Wei-Li Di, David Curtis, Maria Kolatsi-Joannou, Hafsa Hammid, Anna Szőcs, Kristóf Perczel, Erika Maka, Gergely Toldi, Florentina Sava, Christelle Arrondel, Magdolna Kardos, Attila Fintha, Ahmed Hossain, Felipe D’Arco, Mario Kaliakatsos, Jutta Koeglmeier, William Mifsud, Mariya Moosajee, Ana Faro, Eszter Jávorszky, Gábor Rudas, Marwa H. Saied, Salah Marzouk, Kata Kelen, Judit Götze, George Reusz, Tivadar Tulassay, François Dragon, Géraldine Mollet, Susanne Motameny, Holger Thiele, Guillaume Dorval, Peter Nürnberg, András Perczel, Attila J. Szabó, David A. Long, Kazunori Tomita, Corinne Antignac, Aoife M. Waters, Kálmán Tory; Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis; Proceedings of the National Academy of Sciences Jun 2020, 202002328; doi: 10.1073/pnas.2002328117

DOI BRAD record
NEW Tomlinson, A., Lane, J., Julier, G., ..., Payne, A. et al. (2020). Qualitative findings from a systematic review: Visual arts engagement for adults with mental health conditions. Journal of Applied Arts & Health, 11 (3), pp. 281-297. doi: 10.1386/jaah_00042_1.

DOI BRAD record
NEW Scholze, M., Taxvig, C., Kortenkamp, A., ..., Ermler, S. et al. (2020). Quantitative in Vitro to in Vivo Extrapolation (QIVIVE) for Predicting Reduced Anogenital Distance Produced by Anti-Androgenic Pesticides in a Rodent Model for Male Reproductive Disorders. Environmental health perspectives, 2020, 128 (11), 117005, pp. 1-17. doi: 10.1289/EHP6774.

DOI BRAD record
NEW Penn-Nicholson, A., Mbandi, S., Thompson, E., ..., Roberts, T. et al. (2020). RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response. Scientific Reports, 10 (1), 8629, pp. 1 - 21. doi: 10.1038/s41598-020-65043-8.

DOI BRAD record
NEW Goncalves, T., Zoumpoulidou, G., Alvarez-Mendoza, C., Mancusi, C., Collopy, L., Strauss, S., Mittnacht, S. and Tomita, K. (2020). Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by ATR Inhibitors. ACS Pharmacology and Translational Science, 3(6): 1253–1264. doi: 10.1021/acsptsci.0c00125.

DOI BRAD record
NEW Goncalves, T., Zoumpoulidou, G., Alvarez-Mendoza, C., Mancusi, C., Collopy, L., Strauss, S., Mittnacht, S. and Tomita, K. (2020). Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by ATR Inhibitors. ACS Pharmacology & Translational Science, in press (12 pp.). doi: 10.1021/acsptsci.0c00125.

DOI BRAD record
NEW Zhang, B., Cristescu, R., Chrisey, D. and Narayan, R. (2020). Solvent-based extrusion 3D printing for the fabrication of tissue engineering scaffolds. International Journal of Bioprinting, 6 (1), pp. 28 - 42. doi: 10.18063/ijb.v6i1.211.

DOI BRAD record
NEW Chong, W., Wang, W., Lo, C., ..., Tanos, B. et al. (2020). Super-resolution microscopy reveals coupling between mammalian centriole subdistal appendages and distal appendages. eLife, 9, e53580, pp. 1-xx. doi: 10.7554/eLife.53580.

DOI BRAD record
NEW Martin, O., Scholze, M., Ermler, S., McPhie, J., Bopp, S., Kienzler, A., Parissis, N. and Kortenkamp, A. (2020). Ten years of research on synergisms and antagonisms in chemical mixtures: A systematic review and quantitative reappraisal of mixture studies. Martin, O. et al. (2021) 'Ten years of research on synergisms and antagonisms in chemical mixtures: A systematic review and quantitative reappraisal of mixture studies', Environment international, 146, 106206, pp. 1 - 17. doi:10.1016/j.envint.2020.106206.

DOI BRAD record
NEW Lewis, A., Russell, H., Kedzierska, K. et al. (2020). The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability. Clinical Epigenetics 12, 102, pp. 1-9. https://doi.org/10.1186/s13148-020-00889-3

BRAD record
NEW Legler, J., Zalko, D., Jourdan, F., ..., Ermler, S. et al. (2020). The goliath project: Towards an internationally harmonised approach for testing metabolism disrupting compounds. Legler, J., Zalko, D., Jourdan, F., Jacobs, M., Fromenty, B., Balaguer, P., Bourguet, W., Munic Kos, V., Nadal, A., Beausoleil, C., Cristobal, S., Remy, S., Ermler, S., Margiotta-Casaluci, L., Griffin, J. L., Blumberg, B., Chesné, C., Hoffmann, S., Andersson, P. L. and Kamstra, J. H. (2020) ‘The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds’, International Journal of Molecular Sciences, 21(10), 3480, pp. 1-18. doi: 10.3390/ijms21103480.

DOI BRAD record
NEW Philip, K., Lewis, A., Buttery, S., McCabe, C., Manivannan, B., Fancourt, D., Orton, C., Polkey, M. and Hopkinson, N. (2020). The physiological demands of Singing for Lung Health compared to treadmill walking. Philip, K.E.J., Lewis, A., Buttery, S.C., McCabe, C., Manivannan, B., Fancourt, D., Orton, C., Polkey, M.I. and Hopkinson, N.S. 'The physiological demands of Singing for Lung Health compared to treadmill walking', medRxiv, in press, pp. 1-17. doi: 10.1101/2020.12.08.20245746.

DOI BRAD record
NEW Collett, G., Kai, C., William, Y., Mary, G. and Anderson, R. (2020). The psychological consequences of (perceived) ionizing radiation exposure: a review on its role in radiation-induced cognitive dysfunction. International Journal of Radiation Biology, 96 (9), pp. 1104 - 1118, doi: 10.1080/09553002.2020.1793017.

DOI BRAD record
NEW Syeda, A., Dimude, J., Skovgaard, O. and Rudolph, C. (2020). Too much of a good thing: how ectopic DNA replication affects bacterial replication dynamics. Frontiers in Microbiology, 11, 534, pp. 1-21. doi: 10.3389/fmicb.2020.00534.

DOI BRAD record
NEW Sisu, C., Muir, P., Frankish, A. et al. (2020). Transcriptional activity and strain-specific history of mouse pseudogenes. Nature Communications, 11, 3695, pp. 1-14. doi: 10.1038/s41467-020-17157-w.

DOI BRAD record

2019

NEW Meagher, N., Wang, L., Rambau, P., ..., Zhang, B. et al. (2019). A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases. Modern Pathology, 32 (12), pp. 1834 - 1846. doi: 10.1038/s41379-019-0302-0.

DOI BRAD record
NEW Barravecchia, I., De Cesari, C., Pyankova, O., Scebba, F., Pè, M., Forcato, M., Bicciato, S., Foster, H., Bridger, J. and Angeloni, D. (2019). A comprehensive molecular and morphological study of the effects of space flight on human capillary endothelial cells: sample quality assessment and preliminary results. Frontiers in Physiology. Conference Abstract: 39th ISGP Meeting & ESA Life Sciences Meeting. abstract 50, pp. [1-2]. doi: 10.3389/conf.fphys.2018.26.00050.

DOI BRAD record
NEW Deelen, J., Kettunen, J., Fischer, K., ..., Drenos, F. et al. (2019). A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals. Nature Communications, 2019, 10 (1), 3346, pp. 1 - 6. doi: 10.1038/s41467-019-11311-9.

DOI BRAD record
NEW Bubici, C., Lepore, A. and Papa, S. (2019). ASKing No More: The Emerging Role of Dual-Specific Phosphatase 12 in the Regulation of Hepatic Lipid Metabolism. Hepatology, 2019, 70 (4), pp. 1091 - 1094 doi: 10.1002/hep.30851

DOI BRAD record
NEW Ingold, N., Amin, H. and Drenos, F. (2019). Alcohol causes an increased risk of head and neck but not breast cancer in individuals from the UK Biobank study: A Mendelian randomisation analysis. medRxiv, 19002832, pp. 1 - 20. doi: 10.1101/19002832.

DOI BRAD record
NEW Mansell, S., Harvey, A. and Thomas, A. (2019). An exploratory study considering the potential impacts of high-fidelity simulation training on self-evaluated confidence of non-respiratory physiotherapists providing an on-call respiratory physiotherapy service - a mixed methods study. Mansell, S.K., Harvey, A. and Thomas, A.J. (2020) 'An exploratory study considering the potential impacts of high-fidelity simulation training on self-evaluated confidence of non-respiratory physiotherapists providing an on-call respiratory physiotherapy service - a mixed methods study', BMJ Simulation and Technology Enhanced Learning, 6 (4), pp. 199 - 205 (7). doi: 10.1136/bmjstel-2019-000444.

DOI BRAD record
NEW Lewis, A., Dullaghan, D., Townes, H., Green, A., Potts, J. and Quint, J. (2019). An observational cohort study of exercise and education for people with chronic obstructive pulmonary disease not meeting criteria for formal pulmonary rehabilitation programmes. Chronic Respiratory Disease, 2019, 16: (12) doi: 10.1177/1479973119838283

DOI BRAD record
NEW Ghorbani, M., Pousset, F., Tucker, A., Swift, S., Giunti, P., Parkinson, M., Gilbert, D., Liu, X. and Payne, A. (2019). Analysis of Friedreich's ataxia patient clinical data reveals importance of accurate GAA repeat determination in disease prognosis and gender differences in cardiac measures. Ghorbani, Mohammadmersad; Pousset, Françoise; Tucker, Allan; Swift, Stephen; Giunti, Paola; Parkinson, Michael; Gilbert, David; Liu, XiaoHui; Payne, Annette; Analysis of Friedreich's ataxia patient clinical data reveals importance of accurate GAA repeat determination in disease prognosis and gender differences in cardiac measures, Informatics in Medicine Unlocked, 17, 2019, 100266 doi: 10.1016/j.imu.2019.100266

DOI BRAD record
NEW Lewis, A. (2019). CRISPR-Cas9 causes chromosomal instability and re-arrangements in cancer cell lines, detectable by cytogenetic methods. The CRISPR-Journal

BRAD record
NEW Federico, C., Owoka, T., Ragusa, D., ..., Sisu, C. et al. (2019). Deletions of Chromosome 7q Affect Nuclear Organization and HLXB9Gene Expression in Hematological Disorders. Federico, C., Owoka, T., Ragusa, D., Sturiale, V., Caponnetto, D., Leotta, C. G., Bruno, F., Foster, H. A., Rigamonti, S., Giudici, G., Cazzaniga, G., Bridger, J. M., Sisu, C., Saccone, S. and Tosi, S. (2019) ‘Deletions of Chromosome 7q Affect Nuclear Organization and HLXB9Gene Expression in Hematological Disorders’, Cancers, 11(4), 585, pp. 1-19. doi: 10.3390/cancers11040585.

DOI BRAD record
NEW Kumar, J., Chudasama, D., Charlotee, R., Kubista, M., Sjoback, R., Chatterjee, J., Anikin, V., Karteris, E. and Hall, M. (2019). Detection of Abundant Non-Haematopoietic Circulating Cancer-Related Cells in Patients with Advanced Epithelial Ovarian Cancer. Cells, 2019

BRAD record
NEW Vidotto, L., Carvalho, C., Harvey, A. and Jones, M. (2019). Dysfunctional breathing: what do we know?. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2019, 45 (1), pp. 1 - 9 doi: 10.1590/1806-3713/e20170347

DOI BRAD record
NEW Bubici, C. and Papa, S. (2019). Editorial: The Warburg effect regulation under siege: The intertwined pathways in health and disease. Frontiers in Cell and Developmental Biology, 2019, 7 (May) doi: 10.3389/fcell.2019.00080

DOI BRAD record
NEW Karteris, E., Nieddu, V., Piredda, R., Bexel, D., Barton, J., Anderson, J., Sebire, N., Kolluri, K., Janes, S. and Sala, A. (2019). Engineered human mesenchymal stem cells for neuroblastoma therapeutics. Oncology Reports

BRAD record
NEW Al-Qahtani, A., Murugaiah, V., Bashir, H., Pathan, A., Abozaid, S., Makarov, E., Nal, B., Kishore, U. and Al-Ahdal, M. (2019). Full-length human Surfactant Protein A inhibits Influenza A Virus infection of A549 lung epithelial cells: a recombinant form containing neck and lectin domains promotes infectivity. Immunobiology

BRAD record
NEW Tachmazidou, I., Hatzikotoulas, K., Southam, L., ..., Haberland, V. et al. (2019). Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

BRAD record
NEW Apps, M., Pavitt, M., Lewis, A., Orton, C., Sadaka, A., Garner, J., Hind, M., Hopkinson, N., Polkey, M. and Hull, J. (2019). Increasing CPAP (continuous positive airway pressure) leads to increasing transpulmonary pressure with increased activity of the abdominal wall muscles to aid expiration. European Respiratory Society International Congress. Madrid, Spain, 28 September - 2 October 2019.

BRAD record
NEW Katopodis, P., Chudasama, D., Wander, G., Sales, L., Kumar, J., Pandhal, M., Anikin, V., Chatterjee, J., Hall, M. and Karteris, E. (2019). Kinase inhibitors and ovarian cancer. Cancers, 2019, 11 (9), 1357 (17) doi: 10.3390/cancers11091357

DOI BRAD record
NEW Chudasama, D., Katopodis, P., Stone, N., ..., Sisu, C., Karteris, E. et al. (2019). Liquid biopsies in lung cancer: Four emerging technologies and potential clinical applications. Cancers doi: 10.3390/cancers11030331

DOI BRAD record
NEW Britten, O., Ragusa, D., Tosi, S. and Kamel, Y. (2019). MLL-rearranged acute leukemia with t(4;11)(q21;q23) - current treatment options. Is there a role for CAR-T cell therapy?. Britten, O., Ragusa, D., Tosi, S. and Kamel, Y.M. (2019) ‘MLL-Rearranged Acute Leukemia with t(4;11)(q21;q23)—Current Treatment Options. Is There a Role for CAR-T Cell Therapy?’, Cells, 8 (11), 1341, p. 1-22. doi: 10.3390/cells8111341.

DOI BRAD record
NEW Philip, K., Lewis, A. and Hopkinson, N. (2019). Music and dance in chronic lung disease. Breathe, 2019, 15 (2), pp. 116 - 120 doi: 10.1183/20734735.0007-2019

DOI BRAD record
NEW Zhang, B., Huang, Z., Rahi, B., Wang, Q. and Li, M. (2019). Online semi-supervised multi-person tracking with gaussian process regression. (from the Proceedings of the 2018 International Joint Conference on Metallurgical and Materials Engineering (JCMME 2018), Wellington, New Zealand, 10-12 December 2018) MATEC Web of Conferences, 277, 01003, pp. 1-8. doi: 10.1051/matecconf/201927701003.

DOI BRAD record
NEW Clements, C., Bikkul, M., Ofosu, W., Eskiw, C., Tree, D., Makarov, E., Kill, I. and Bridger, J. (2019). Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways. Biogerontology 20 (3), pp. 337 - 358. doi: 10.1007/s10522-019-09807-4.

DOI BRAD record
NEW Gruffydd-Jones, K., Keeley, D., Knowles, V., ..., Harvey, A. et al. (2019). Primary care implications of the British Thoracic Society Guidelines for bronchiectasis in adults 2019. npj Primary Care Respiratory Medicine, 2019, pp. 1 - 7 doi: 10.1038/s41533-019-0136-8

DOI BRAD record
NEW Slijepcevic, P. (2019). Principles of information processing and natural learning in biological systems. Journal for General Philosophy of Science, 2019, pp. 1 - 19 (19) doi: 10.1007/s10838-019-09471-9

DOI BRAD record
NEW Justice, A., Karaderi, T., Highland, H., ..., Drenos, F. et al. (2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics, 51, pp. 452 - 469. doi: 10.1038/s41588-018-0334-2.

DOI BRAD record
NEW Lewis, A., Axson, E., Potts, J., Tarnowska, R., Vioix, H. and Quint, J. (2019). Protocol for a systematic literature review and network meta-analysis of the clinical benefit of inhaled maintenance therapies in chronic obstructive pulmonary disease. BMJ Open, 9 (2), e025048, pp. 1 - 7. doi: 10.1136/bmjopen-2018-025048.

DOI BRAD record
NEW Lightbody, G., Haberland, V., Browne, F., Taggart, L., Zheng, H., Parkes, E. and Blayney, J. (2019). Review of applications of high-throughput sequencing in personalized medicine: Barriers and facilitators of future progress in research and clinical application. Briefings in Bioinformatics, 20 (5), pp. 1795 - 1811. doi: 10.1093/bib/bby051.

DOI BRAD record
NEW Lucendo-Villarin, B., Rashidi, H., Alhaque, S., Fischer, L., Meseguer-Ripolles, J., Wang, Y., O'Farrelly, C., Themis, M. and Hay, D. (2019). Serum free production of three-dimensional human hepatospheres from pluripotent stem cells. Journal of visualized experiments : JoVE, 149, e59965, pp. 1-8. doi: 10.3791/59965.

DOI BRAD record
NEW Karteris, E., Kumar, J., Murugaiah, V. et al. (2019). Surfactant Protein D as a Potential Biomarker and Therapeutic Target in Ovarian Cancer. Frontiers in Oncology, 9, 542, pp. 1-14. doi: 10.3389/fonc.2019.00542

DOI BRAD record
NEW Lewis, A. and Hopkinson, N. (2019). Tai Chi Movements for Wellbeing – evaluation of a British Lung Foundation pilot. Perspectives in Public Health, 2019, 20 (11), pp. 1 - 9 doi: 10.1177/1757913919872515

DOI BRAD record
NEW Rudolph, C., Corocher, T., Grainge, I. and Duggin, I. (2019). Termination of DNA Replication in Prokaryotes. eLS, 2019 doi: 10.1002/9780470015902.a0001056.pub3

DOI BRAD record
NEW Ragusa, D., Makarov, E., Britten, O., Moralli, D., Green, C. and Tosi, M. (2019). The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): revised characterisation of cytogenetic features. Cancer Reports doi: 10.1002/cnr2.1207

DOI BRAD record
NEW Huguet, F., Flynn, S. and Vagnarelli, P. (2019). The Role of Phosphatases in Nuclear Envelope Disassembly and Reassembly and Their Relevance to Pathologies. Cells, 8 (7), pp. 687 - 687 doi: 10.3390/cells8070687

DOI BRAD record
NEW Thomas, R., Trapani, D., Goodyer-Sait, L., ..., Lewis, A. et al. (2019). The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression. Scientific Reports, 2019, 9 (1), Article number: 13463 (10) doi: 10.1038/s41598-019-49952-x

DOI BRAD record
NEW Lewis, A., Bruton, A. and Donovan-Hall, M. (2019). Uncertainty prior to pulmonary rehabilitation in primary care. Chronic Respiratory Disease, 2014, 11 (3), pp. 173 - 180 doi: 10.1177/1479972314539981

DOI BRAD record
NEW Amin, H., Drenos, F. and Blakemore, A. (2019). Variation at the Klotho gene locus does not affect cognitive function in up to 335,074 British Caucasians in the UK Biobank. bioRxiv, 838409, pp. 1 - 24. doi: 10.1101/838409.

DOI BRAD record

2018

NEW Yao, H., Zhang, B., Zhang, P. and Li, M. (2018). A novel kernel for text classification based on semantic and statistical information. Computing and Informatics, 37 (4), pp. 992 - 1010. doi: 10.4149/cai_2018_4_992.

DOI BRAD record
NEW Midgley-Smith, S., Dimude, J. and Rudolph, C. (2018). A role for 3’ exonucleases at the final stages of chromosome duplication in Escherichia coli. Nucleic Acids Research

BRAD record
NEW Hernandez, V. and Seda, M. (2018). An FDA-Approved Drug Screen for Compounds Influencing Craniofacial Skeletal Development and Craniosynostosis. Seda M, Geerlings M, Lim P, Jeyabalan-Srikaran J, Cichon AC, Scambler PJ, Beales PL, Hernandez-Hernandez V, Stoker AW, Jenkins D. An FDA-Approved Drug Screen for Compounds Influencing Craniofacial Skeletal Development and Craniosynostosis. Molecular syndromology. 2019;10(1-2):98-114.

BRAD record
NEW Hill, A., Sullivan, A., Chalmers, J., ..., Harvey, A. et al. (2018). British Thoracic Society Guideline for bronchiectasis in adults. Hill, A.T., Sullivan, A.L., Chalmers, J.D., De Soyza, A., Elborn, J.S., Floto, R.A., Grillo, L., Gruffydd-Jones, K., Harvey, A., S Haworth, C., Hiscocks, E., R Hurst, J., Johnson, C., Kelleher, W.P., Bedi, P., Payne, K., Saleh, H., Screaton, N.J., Smith, M., Tunney, M., Whitters, D., Wilson, R. and Loebinger, M.R. (2019) 'British Thoracic Society Guideline for bronchiectasis in adults', Thorax, 74 (Suppl 1), pp. 1-69. doi: 10.1136/thoraxjnl-2018-212463.

DOI BRAD record
NEW Hill, A., Sullivan, A., Chalmers, J., ..., Harvey, A. et al. (2018). British Thoracic Society guideline for bronchiectasis in adults (BMJ Open). Hill AT, Sullivan AL, Chalmers JD, et al. (2018) 'British Thoracic Society guideline for bronchiectasis in adults', BMJ Open Respiratory Research 5:e000348, pp. 1-16. doi:10.1136/bmjresp-2018-000348

DOI BRAD record
NEW Lewis, A. and Thomas, J. (2018). COPD and Singing for Lung Health: A Patient and Clinician Perspective. Pulmonary Therapy, 2018, 4 (2), pp. 121 - 124 doi: 10.1007/s41030-018-0063-9

DOI BRAD record
NEW Harvey, A., Domislic, B. and Shannon, H. (2018). Developmental outcome measures in neonatal physiotherapy services of the United Kingdom: a survey of current use, and facilitators and barriers to their implementation. Association of Paediatric Chartered Physiotherapists Journal, 9 (1)

BRAD record
NEW Rogers‑Broadway, K., Kumar, J., Sisu, C., ..., Karteris, E. et al. (2018). Differential expression of mTOR components in endometriosis and ovarian cancer: Effects of rapalogues and dual kinase inhibitors on mTORC1 and mTORC2 stoichiometry. International Journal of Molecular Medicine, 2019, 43, pp. 47-56

BRAD record
NEW Papa, S. and Bubici, C. (2018). Feeding the Hedgehog: A new meaning for JNK signalling in liver regeneration. Journal of Hepatology, 2018 doi: 10.1016/j.jhep.2018.05.026

DOI BRAD record
NEW Karteris, E., Patel, V., Chen, J. et al. (2018). Functional Cardiac Orexin Receptors: Role of Orexin-B/Orexin 2 Receptor in Myocardial Protection. Clinical Science doi: 10.1042/CS20180150.

DOI BRAD record
NEW Frankish, A., Diekhans, M., Ferreira, A., ..., Sisu, C. et al. (2018). GENCODE reference annotation for the human and mouse genomes. Nucleic Acids Research, 2018 doi: 10.1093/nar/gky955

DOI BRAD record
NEW Slijepcevic, P. (2018). Genome dynamics over evolutionary time: “C-value enigma” in light of chromosome structure. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2018 doi: 10.1016/j.mrgentox.2018.05.005

DOI BRAD record
NEW Lee, N., Carella, M., Papa, S. and Bubici, C. (2018). High expression of glycolytic genes in Cirrhosis correlates with the risk of developing liver cancer. Frontiers in Cell and Developmental Biology, 2018, 6 (OCT) doi: 10.3389/fcell.2018.00138

DOI BRAD record
NEW Moris, N., Edri, S., Seyres, D., Kulkarni, R., Domingues, A., Balayo, T., Frontini, M. and Pina, C. (2018). Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity. Stem Cells, 36 (12), pp. 1828 - 1838. doi: 10.1002/stem.2919.

DOI BRAD record
NEW Tummala, H., Collopy, L., Walne, A., ..., Tomita, K. et al. (2018). Homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita–like phenotypes. Hemanth Tummala, Laura C. Collopy, Amanda J. Walne, Alicia Ellison, Shirleny Cardoso, Tekin Aksu, Nese Yarali, Deniz Aslan, Rüştü Fikret Akata, Juliana Teo, Zhou Songyang, Nikolas Pontikos, Jude Fitzgibbon, Kazunori Tomita, Tom Vulliamy, Inderjeet Dokal; Homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita–like phenotypes. Blood 2018; 132 (12): 1349–1353. doi: 10.1182/blood-2018-03-837799

DOI BRAD record
NEW Kouser, L., Paudyal, B., Kaur, A., Stenbeck, G., Jones, L., Abozaid, S., Stover, C., Flauhat, E., Sim, R. and Kishore, U. (2018). Human Properdin Opsonizes Nanoparticles and Triggers a Potent Pro-inflammatory Response by Macrophages without Involving Complement Activation. Kouser L, Paudyal B, Kaur A, Stenbeck G, Jones LA, Abozaid SM, Stover CM, Flahaut E, Sim RB and Kishore U (2018) Human Properdin Opsonizes Nanoparticles and Triggers a Potent Pro-inflammatory Response by Macrophages without Involving Complement Activation. Front. Immunol. 9:131. doi: 10.3389/fimmu.2018.00131

DOI BRAD record
NEW Karteris, E., Kawan, M., Kyrou, I., Ramanjaneya, M., Williams, K., Jeyaneethi, J. and Randeva, H. (2018). Involvement of the glutamine RF-amide peptide (QRFP) and its cognate receptor GPR103 in prostate cancer. Journal of Oncology doi: 10.3892/or.2018.6893

DOI BRAD record
NEW Vagnarelli, P. and Sales Gil, R. (2018). Ki-67: More Hidden behind a ‘Classic Proliferation Marker. Trends in Biochemical Sciences, 2018, 43(10): 747 - 748 doi: 10.1016/j.tibs.2018.08.004

DOI BRAD record
NEW Tijani, M., Munis, A., Perry, C., ..., Themis, M. et al. (2018). Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes. Molecular Therapy - Methods and Clinical Development, 2018, 10 pp. 303 - 312 doi: 10.1016/j.omtm.2018.07.013

DOI BRAD record
NEW Dalke, C., Neff, F., Bains, S., ..., Slijepcevic, P. et al. (2018). Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk. Dalke, C., Neff, F., Bains, S.K. et al. Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk. Radiat Environ Biophys doi: 10.1007/s00411-017-0728-z

DOI BRAD record
NEW Domingues, A., Kulkarni, R., Giotopoulos, G., ..., Pina, C. et al. (2018). Loss of Kat2A Enhances Transcriptional Noise and Depletes Acute Myeloid Leukemia Stem-Like Cells. bioRxiv, 2018 446096 doi: 10.1101/446096

DOI BRAD record
NEW Yue, W., Wang, Z., Chen, H., Payne, A. and Liu, X. (2018). Machine Learning with Applications in Breast Cancer Diagnosis and Prognosis. Designs, 2018, 2 (2), pp. 13 - 13 doi: 10.3390/designs2020013

DOI BRAD record
NEW Al-Allaf, F., Abduljaleel, Z., Athar, M., ..., Themis, M. et al. (2018). Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia. Non-coding RNA Research, 2018, 4 (1), pp. 1 - 14 doi: 10.1016/j.ncrna.2018.11.005

DOI BRAD record
NEW Aveyard, P., Lindson, N., Tearne, S., ..., Anderson, R. et al. (2018). Nicotine preloading for smoking cessation: the Preloading RCT. Health Technology Assessment, 22(41). doi: 10.3310/hta22410.

DOI BRAD record
NEW Sirunyan, A., Tumasyan, A., Adam, W., ..., Tosi, S. et al. (2018). Observation of the chi(b1)(3P) and chi(b2)(3P) and Measurement of their Masses. PHYSICAL REVIEW LETTERS, 2018, 121 (9), pp. ? - ? (17) doi: 10.1103/PhysRevLett.121.092002

DOI BRAD record
NEW Dimude, J., Stein, M., Andrzejewska, E., Khalifa, M., Gajdosova, A., Retkute, R., Skovgaard, O. and Rudolph, C. (2018). Origins Left, Right, and Centre: Increasing the Number of Initiation Sites in the Escherichia coli Chromosome. Dimude, J., Stein, M., Andrzejewska, E., Khalifa, M., Gajdosova, A., Retkute, R., Skovgaard, O. and Rudolph, C. (2018) ‘Origins Left, Right, and Centre: Increasing the Number of Initiation Sites in the Escherichia coli Chromosome’, Genes, 9 (8), 376, pp. 1-21. doi: 10.3390/genes9080376.

DOI BRAD record
NEW Vagnarelli, P. and Alessi, D. (2018). PP1 Phosphatase Complexes: Undruggable No Longer. Cell, 2018, 174 pp. 1049 - 1051 doi: 10.1016/j.cell.2018.08.007

DOI BRAD record
NEW Sirunyan, A., Tumasyan, A., Adam, W., ..., Tosi, S. et al. (2018). Precision measurement of the structure of the CMS inner tracking system using nuclear interactions.

BRAD record
NEW Karteris, E. (2018). Prognostic value of the DNA Integrity Index in patients with malignant lung tumours.

BRAD record
NEW Chudasama, D., Aladag, Z., Felicien, M., Hall, M., Beeson, J., Asadi, N., Gidron, Y., Karteris, E. and Anikin, V. (2018). Prognostic value of the DNA integrity index in patients with malignant lung tumors. Oncotarget, 2018, 9 (30), pp. 21281 - 21288 doi: 10.18632/oncotarget.25086

DOI BRAD record
NEW Vagnarelli, P. and Sales Gil, R. (2018). Protein Phosphatases in chromatin structure and function. BBA Molecular Cell Research, 2019, 1866(1): 90 - 101 doi: 10.1016/j.bbamcr.2018.07.016

DOI BRAD record
NEW Quint, J., Moore, E., Lewis, A. et al. (2018). Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research. npj Primary Care Respiratory Medicine, 2018, 28 (1): 21 doi: 10.1038/s41533-018-0089-3

DOI BRAD record
NEW Roller, M., Navarro, F., Fiddes, I., ..., Sisu, C. et al. (2018). Repeat associated mechanisms of genome evolution and function revealed by theMus caroliandMus paharigenomes. Genome Res, 2018 doi: 10.1101/gr.234096.117

DOI BRAD record
NEW Tzelepis, K., De Braekeleer, E., Aspris, D., ..., Pina, C. et al. (2018). SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Tzelepis, K., De Braekeleer, E., Aspris, D. et al. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nat Commun 9, 5378 (2018). doi: 10.1038/s41467-018-07620-0

DOI BRAD record
NEW Lewis, A., Cave, P. and Hopkinson, N. (2018). Singing for Lung Health: service evaluation of the British Lung Foundation programme. Perspectives in Public Health, 2018, 138 (4), pp. 215 - 222 doi: 10.1177/1757913918774079

DOI BRAD record
NEW Lilue, J., Doran, A., Fiddes, I., ..., Sisu, C. et al. (2018). Sixteen diverse laboratory mouse reference genomes define strain specific haplotypes and novel functional loci. Nature Genetics, 2018 doi: 10.1038/s41588-018-0223-8

DOI BRAD record
NEW Mansfield, L., Kay, T., Meads, C., ..., Payne, A. et al. (2018). Sport and dance interventions for healthy young people (15-24 years) to promote subjective wellbeing: A systematic review. Mansfield, L., Kay, T., Meads, C., Grigsby Duffy, L., Lane, J., John, A., Daykin, N., Dolan, P., Testoni, S., Julier, G., Payne, A., Tomlinson, A. and Victor, C. (2018) Sport and dance interventions for healthy young people (15–24 years) to promote subjective well-being: a systematic review BMJ Open 8, e020959, pp. 1-6. doi: 10.1136/bmjopen-2017-020959.

DOI BRAD record
NEW Vidotto, L., Bigliassi, M., Jones, M., Harvey, A. and Carvalho, C. (2018). Stop Thinking! I Can't! Do Attentional Mechanisms Underlie Primary Dysfunctional Breathing?. Frontiers in Physiology. 9, 782, pp. 1-4. doi: 10.3389/fphys.2018.00782.

DOI BRAD record
NEW Yang, T., Chong, W., Wang, W., ..., Tanos, B. et al. (2018). Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components. Yang, T.T., Chong, W., Wang, W.-J. Mazo, G., Tanos, B., Chen, Y.D., Weng, R.R., Huang, C.-E., ,Jane, W.N., Tsou, M-F.B. and Liao, J.-C. (2018) 'Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components. Nature Communications, 9 (1), 2023, pp. 1-11.. doi: 10.1038/s41467-018-04469-1.

DOI BRAD record
NEW Bikkul, M., Faragher, R., Worthington, G., ..., Slijepcevic, P., Makarov, E. et al. (2018). Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform. Bikkul, M.U., Faragher, R.G.A., Worthington, G., Meinke, P., Kerr, A.R.W., Sammy, A., Riyahi, K., Horton, D., Schirmer, E.C., Hubank, M., Kill, I.R., Anderson, R.M., Slijepcevic, P., Makarov, E. and Bridger, J.M. (2019) 'Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform', Genes, Chromosomes and Cancer, 58(6), pp. 341-356. doi: 10.1002/gcc.22711.

DOI BRAD record
NEW Papa, S., Choy, P. and Bubici, C. (2018). The ERK and JNK pathways in the regulation of metabolic reprogramming. Oncogene doi: 10.1038/s41388-018-0582-8

DOI BRAD record
NEW Lewis, A., Platt, J., Gent, P., Cave, P. and Young, R. (2018). The Lung Cycle – a day of creative investigation into singing for breathing. [rb&hArts newspaper], 2018, pp. 1 - 8

BRAD record
NEW Hemani, G., Zheng, J., Elsworth, B., ..., Haberland, V. et al. (2018). The MR-base platform supports systematic causal inference across the human phenome. eLife, 7, e34408, pp. 1 - 29. doi: 10.7554/eLife.34408.

DOI BRAD record
NEW Themis, M. (2018). Three-dimensional cell culture: From evolution to revolution. Philos Trans R Soc Lond B Biol Sci, 2018, 373 pp. 1750 - 1750 doi: 10.1098/rstb.2017.0216

DOI BRAD record
NEW Zhang, B., Li, S., Huang, Z., Rahi, B., Wang, Q. and Li, M. (2018). Transfer learning-based online multiperson tracking with Gaussian process regression. Concurrency Computation, 2018, 30 (23):e4917 (11) doi: 10.1002/cpe.4917

DOI BRAD record

2017

NEW Maund, P., Ermler, S., Widschwendter, M. and Silva, E. (2017). Abstract P1-04-09: The missing link: Chemicals, epigenetics and breast cancer. Poster Session Abstracts, 2017 doi: 10.1158/1538-7445.sabcs16-p1-04-09

DOI BRAD record
NEW Irshad, S., Bansal, M., Guarnieri, P., ..., Lewis, A. et al. (2017). Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer. Irshad S, Bansal M, Guarnieri P, Davis H, Al Haj Zen A, Baran B, Pinna CM, Rahman H, Biswas S, Bardella C, Jeffery R. Bone morphogenetic protein and Notch signalling crosstalk in poor‐prognosis, mesenchymal‐subtype colorectal cancer. The Journal of pathology. 2017 Jun;242(2):178-92. doi: 10.1002/path.4891

DOI BRAD record
NEW Castro, I., Sales Gil, R., Ligammari, L., Di Giacinto, M. and Vagnarelli, P. (2017). CDK1 and PLK1 co-ordinate the disassembly and re-assembly of the Nuclear Envelope in vertebrate mitosis. Castro I. et al. (20180 'CDK1 and PLK1 coordinate the disassembly and reassembly of the nuclear envelope in vertebrate mitosis', Oncotarget, 9, pp. 7763-7773. doi: 10.18632/oncotarget.23666.

DOI BRAD record
NEW van der Laan, S., Fall, T., Soumaré, A., ..., Drenos, F. et al. (2017). Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. Journal of the American College of Cardiology, 2016, 68 (9), pp. 934 - 945 doi: 10.1016/j.jacc.2016.05.092

DOI BRAD record
NEW Holzinger, E., Verma, S., Moore, C., ..., Drenos, F. et al. (2017). Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals. BioData Mining, 2017, 10 (1) doi: 10.1186/s13040-017-0145-5

DOI BRAD record
NEW Cantarella, C., Ragusa, D., Giammanco, M. and Tosi, S. (2017). Folate deficiency as predisposing factor for childhood leukaemia: A review of the literature.

BRAD record
NEW Linne, H., Yasaei, H., Marriott, A., Harvey, A., Mokbel, K., Newbold, R. and Roberts, T. (2017). Functional role of SETD2, BAP1, PARP-3 and PBRM1 candidate genes on the regulation of hTERT gene expression. Linne H, Yasaei H, Marriott A, Harvey A, Mokbel K, Newbold R, Roberts T. Functional role of SETD2, BAP1, PARP-3 and PBRM1 candidate genes on the regulation of hTERT gene expression. Oncotarget. 2017 Sep 5;8(37):61890. doi: 10.18632/oncotarget.18712

DOI BRAD record
NEW Federico, C., Pappalardo, A., Ferrito, V., Tosi, S. and Saccone, S. (2017). Genomic properties of chromosomal bands are linked to evolutionary rearrangements and new centromere formation in primates. Chromosome Research, (2017)

BRAD record
NEW Chudasama, D., Bo, V., Hall, M., ..., Harvey, A., Karteris, E. et al. (2017). Identification of novel cancer biomarkers of prognostic value using specific gene regulatory networks (GRN): a novel role of RAD51AP1 for ovarian and lung cancers. Chudasama D, Bo V, Hall M, Anikin V, Jeyaneethi J, Gregory J, Pados G, Tucker A, Harvey A, Pink R, Karteris E. Identification of cancer biomarkers of prognostic value using specific gene regulatory networks (GRN): a novel role of RAD51AP1 for ovarian and lung cancers. Carcinogenesis. 2018 Mar 8;39(3):407-17. doi: 10.1093/carcin/bgx122

DOI BRAD record
NEW Tumasyan, A., Adam, W., Asilar, E., ..., Tosi, S. et al. (2017). Measurements of the pp -> W gamma gamma and pp -> Z gamma gamma cross sections and limits on anomalous quartic gauge couplings at root s=8 TeV. JOURNAL OF HIGH ENERGY PHYSICS, 2017, (10), pp. ? - ? (36) doi: 10.1007/JHEP10(2017)072

DOI BRAD record
NEW Vagnarelli, P., Zhiteneva, A., Bonfiglio, J., Makarov, A., Colby, T., Schirmer, E., Matic, I. and Earnshaw, W. (2017). Mitotic post-translational modifications of histones promote chromatin compaction in vitro. Open Biology

BRAD record
NEW Wagner, R., Stubiger, G., Veigel, D., ..., Karteris, E. et al. (2017). Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells. Oncotarget, 2017

BRAD record
NEW de Castro, I., Amin, H., Vinciotti, V. and Vagnarelli, P. (2017). Network of phosphatases and HDAC complexes at repressed chromatin. Cell Cycle, 16 (21), pp. 2011-2017. doi: 10.1080/15384101.2017.1371883.

DOI BRAD record
NEW Kraja, A., Cook, J., Warren, H., ..., Drenos, F. et al. (2017). New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circulation. Cardiovascular genetics, 10 (5), (2017) doi: 10.1161/circgenetics.117.001778

DOI BRAD record
NEW Federico, C., Leotta, C., Bruno, F., Longo, A., Owoka, T., Tosi, S. and Saccone, S. (2017). Nuclear repositioning of the non-translocated HLXB9 allele in the leukaemia cell line GDM-1 harbouring a t(6;7)(q23;q36). Cytogenetic and Genome Research

BRAD record
NEW Tumasyan, A., Adam, W., Asilar, E., ..., Tosi, S. et al. (2017). Particle-flow reconstruction and global event description with the CMS detector. Journal of Instrumentation, 2017, 12 (10), pp. P10003 - P10003 doi: 10.1088/1748-0221/12/10/P10003

DOI BRAD record
NEW Buttery, S., Lewis, A., Oey, I., Hargrave, J., Waller, D., Steiner, M., Shah, P., Kemp, S., Jordan, S. and Hopkinson, N. (2017). Patient experience of lung volume reduction procedures for emphysema: a qualitative service improvement project. ERJ Open Research, 2017, 3 (3): 00031 (7 pp.) doi: 10.1183/23120541.00031-2017

DOI BRAD record
NEW Chudasama, D., Burnside, N., Beeson, J., Karteris, E., Rice, A. and Anikin, V. (2017). Perioperative detection of circulating tumour cells in patients with lung cancer. Oncology Letters, 2017, 14(2), pp. 1281 - 1286 doi: 10.3892/ol.2017.6366

DOI BRAD record
NEW Vasu, V., Turner, K., George, S., Greenall, J., Slijepcevic, P. and Griffin, D. (2017). Preterm infants have significantly longer telomeres than their term born counterparts. PLOS ONE, 12(6), e0180082, pp. 1-16, doi: 10.1371/journal.pone.0180082.

DOI BRAD record
NEW Sales Gil, R., Castro, I., Berihun, J. and Vagnarelli, P. (2017). Protein Phosphatases at the Nuclear Envelope. Sales Gil, R. et al. (2018 ) 'Protein phosphatases at the nuclear envelope', Biochemical Society Transactions, 46(1), pp. 173 - 182. doi: 10.1042/BST20170139.

DOI BRAD record
NEW Turcot, V., Lu, Y., Highland, H., ..., Drenos, F. et al. (2017). Protein-altering Variants Associated with Body Mass Index Implicate Pathways that Control Energy Intake and Expenditure in Obesity. Nature genetics, 2018, 50 (1), pp. 26 - 41 doi: 10.1038/s41588-017-0011-x

DOI BRAD record
NEW Marouli, E., Graff, M., Medina-Gomez, C., ..., Drenos, F. et al. (2017). Rare and low-frequency coding variants alter human adult height. Nature, 2017, 542 (7640), pp. 186 - 190 doi: 10.1038/nature21039

DOI BRAD record
NEW de Castro, I., Budzak, J., Di Giacinto, M., ..., Vagnarelli, P. et al. (2017). Repo-Man/PP1 regulates heterochromatin formation in interphase. de Castro, I., Budzak, J., Di Giacinto, M. et al. Repo-Man/PP1 regulates heterochromatin formation in interphase. Nat Commun 8, 14048 doi: 10.1038/ncomms14048

DOI BRAD record
NEW Russell, A., Cave, P., Taylor, K., Lewis, A., Hopkinson, N. and Wells, A. (2017). Rhythm and song: Breath management in Idiopathic Interstitial Pneumonias (IIP's). Pilot study. Physiotherapists, 2017 doi: 10.1183/1393003.congress-2017.pa2536

DOI BRAD record
NEW Baker, A., Huang, W., Wang, X., ..., Lewis, A. et al. (2017). Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Baker, A., Huang, W., Wang, X.M. et al. Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Nat Commun 8, 1998 (2017). https://doi.org/10.1038/s41467-017-02295-5

DOI BRAD record
NEW Lewis, A., Cave, P. and Hopkinson, N. (2017). Singing for Lung Health: a qualitative assessment of a British Lung Foundation programme for group leaders. BMJ Open Respiratory Research, 2017, 4 (1), pp. e000216 - e000216 doi: 10.1136/bmjresp-2017-000216

DOI BRAD record
NEW Aubert, B., Barate, R., Bona, M., ..., Tosi, S. et al. (2017). Study of the D*(sJ)(2317)(+) and D-sJ(2460)(+) mesons in inclusive cc(-) production near root s=10.6 GeV. Physical Review D, 2006, 74 (3) doi: 10.1103/PhysRevD.74.032007

DOI BRAD record
NEW Kortenkamp, A., Martin, O., Baynes, A., Silva, E., Petersen, M. and Hass, U. (2017). Supporting the organisation of a workshop on thyroid disruption – final report. Kortenkamp, A., Martin, O., Baynes, A., Silva, E., Petersen, M.A. and Hass, U. (2017) Supporting the organisation of a workshop on thyroid disruption – final report. Luxembourg : Publications Office of the European Union, 162 pp. ISBN: 978-92-79-73427-4. doi: 10.2779/921523

DOI BRAD record
NEW Thain, A., Silva Vidotto, L., Harvey, A. and Jones, M. (2017). The Prevalence of Dysfunctional Breathing and its Association with Personality Type in a University Population. Thorax 72, pp. A161-A162. doi: 10.1136/thoraxjnl-2017-210983.286.

DOI BRAD record
NEW Makarov, E., Shtam TA, Kovalev RA, Pantina RA, Varfolomeeva EY and Filatov MV (2017). The rare nonsense mutation in p53 triggers alternative splicing to produce a protein capable of inducing apoptosis. Makarov EM, Shtam TA, Kovalev RA, Pantina RA, Varfolomeeva EY, et al. (2017) The rare nonsense mutation in p53 triggers alternative splicing to produce a protein capable of inducing apoptosis. PLOS ONE 12(9): e0185126. doi: 10.1371/journal.pone.0185126

DOI BRAD record
NEW Moiseeva, V., Amelina, H., Collopy, L., Armstrong, C., Pearson, S. and Tomita, K. (2017). The telomere bouquet facilitates meiotic prophase progression and exit in fission yeast. Cell Discovery, 2017, 3 doi: 10.1038/celldisc.2017.41

DOI BRAD record
NEW Daykin, N., Mansfield, L., Meads, C., ..., Payne, A. et al. (2017). What Works for Wellbeing? A systematic review of wellbeing outcomes for music and singing in adults. Daykin N. et al. (2018) 'What works for wellbeing? A systematic review of wellbeing outcomes for music and singing in adults', Perspectives in Public Health, 138 (1), pp. 39 - 46. doi: 10.1177/1757913917740391.

DOI BRAD record

2016

NEW Tzelepis, K., Koike-Yusa, H., De Braekeleer, E., ..., Pina, C. et al. (2016). A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia. Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M. A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia. Cell reports. 2016 Oct 18;17(4):1193-205. doi: 10.1016/j.celrep.2016.09.079

DOI BRAD record
NEW Altshuler, D., Durbin, R., Abecasis, G., ..., Sisu, C. et al. (2016). A global reference for human genetic variation. NATURE, 2015, 526 (7571), pp. 68 - + (20) doi: 10.1038/nature15393

DOI BRAD record
NEW Silva, E., Ermler, S., Widschwendter, M. and Maund, P. (2016). Abstract P6-05-03: Investigating the effects of low-dose mixtures of environmental contaminants on breast cancer initiation. Poster Session Abstracts, 2017 doi: 10.1158/1538-7445.sabcs16-p6-05-03

DOI BRAD record
NEW Kargaran, P., Yasaei, H., Anjomani-Virmouni, S., Mangiapane, G. and Slijepcevic, P. (2016). Analysis of alternative lengthening of telomere markers in BRCA1 defective cells. Genes Chromosomes and Cancer, 55 (11): pp. 864 - 876, (2016) doi: 10.1002/gcc.22386

DOI BRAD record
NEW Pednekar, L., Pathan, A., Paudyal, B., ..., Stenbeck, G. et al. (2016). Analysis of the interaction between globular head modules of candidate receptor gC1qR. Pednekar, L., Pathan, A.A., Paudyal, B., Tsolaki, A.G., Kaur, A., Abozaid, S.M., Kouser, L., Khan, H,A., Peerschke, E.I., Shamji, M.H., Stenbeck, G., Ghebrehiwet, B. and Kishore, U. (2016) 'Analysis of the Interaction between Globular Head Modules of Human C1q and Its Candidate Receptor gC1qR', Frontiers in Immunology, 7, 567, pp. 1-12. doi: 10.3389/fimmu.2016.00567.

DOI BRAD record
NEW Beaney, K., Cooper, J., Drenos, F. and Humphries, S. (2016). Assessment of the clinical utility of adding common single nucleotide polymorphism genetic scores to classical risk factor algorithms in coronary heart disease risk prediction in UK men. Clinical Chemistry and Laboratory Medicine, 2017, 55 (10), pp. 1605 - 1613 doi: 10.1515/cclm-2016-0984

DOI BRAD record
NEW Wijesuriya, S., Burugapalli, K., Mackay, R., Ajaezi, G. and Balachandran, W. (2016). Chemically roughened solid silver: A simple, robust and broadband SERS substrate. Sensors, 16(10): 1742, (2016) doi: 10.3390/s16101742

DOI BRAD record
NEW Rogers-Broadway, K., Chudasama, D., Pados, G., Tsolakidis, D., Goumenou, A., Hall, M. and Karteris, E. (2016). Differential effects of rapalogues, dual kinase inhibitors on human ovarian carcinoma cells in vitro. International Journal of Oncology, 49(1): pp. 133 - 143, (2016) doi: 10.3892/ijo.2016.3531

DOI BRAD record
NEW Bourton, E. (2016). EP-2069: CDC73 deficiency: a syndrome with multiple tumours is predicted to show excessive radiosensitivity. ESTRO 35, (2016)

BRAD record
NEW Slijepcevic, P. (2016). Evolutionary Epistemology: Reviewing and Reviving with New Data the Research Programme for Distributed Biological Intelligence. BioSystems

BRAD record
NEW Dong, W., Yang, D., Zhou, X., Kastiukas, G. and Zhang, B. (2016). Experimental and numerical investigations on fracture process zone of rock-concrete interface. Dong, W. et al. (2017) 'Experimental and numerical investigations on fracture process zone of rock-concrete interface', Fatigue and Fracture of Engineering Materials and Structures, 40 (5), pp 820 - 835. doi: 10.1111/ffe.12558.

DOI BRAD record
NEW Cheng, T., Thompson, D., O'Mara, T., ..., Lewis, A. et al. (2016). Five endometrial cancer risk loci identified through genome-wide association analysis. Cheng, T., Thompson, D., O'Mara, T. et al. Five endometrial cancer risk loci identified through genome-wide association analysis. Nat Genet 48, 667–674 (2016). doi: 10.1038/ng.3562

DOI BRAD record
NEW Corda, G., Sala, G., Lattanzio, R., ..., Ermler, S., Silva, E., Vagnarelli, P. et al. (2016). Functional and prognostic significance of the genomic amplification of frizzled receptor 6 ( FZD6 ) in breast cancer. Corda G, Sala G, Lattanzio R, Iezzi M, Sallese M, Fragassi G, Lamolinara A, Mirza H, Barcaroli D, Ermler S, Silva E. Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer. The Journal of pathology. 2017 Feb;241(3):350-61. doi: 10.1002/path.4841

DOI BRAD record
NEW Ghorbani, M., Payne, A. and Themis, M. (2016). Genome wide classification and characterisation of CpG sites in cancer and normal cells. Computers in Biology and Medicine, 68, pp. 57-66, (2016) doi: 10.1016/j.compbiomed.2015.09.023

DOI BRAD record
NEW Warren, H., Evangelou, E., Cabrera, C., ..., Drenos, F. et al. (2016). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature Genetics, 2017, 49 (3), pp. 403 - 415 doi: 10.1038/ng.3768

DOI BRAD record
NEW Kaur, A., Sultan, S., Murugaiah, V., Pathan, A., Alhamlan, F., Karteris, E. and Kishore, U. (2016). Human C1q Induces Apoptosis in an Ovarian Cancer Cell Line via Tumor Necrosis Factor. Frontiers in Immunology, 7, 599, pp. 1- 13. doi: 10.3389/fimmu.2016.00599.

DOI BRAD record
NEW De, R., Verma, S., Holzinger, E., ..., Drenos, F. et al. (2016). Identifying gene–gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts. Human Genetics, 2017, 136 (2), pp. 165 - 178 doi: 10.1007/s00439-016-1738-7

DOI BRAD record
NEW Chudasama, D., Freydina, M., Freidin, M., Leung, M., Fernandez, A., Rice, A., Nicholson, A., Karteris, E., Anikin, V. and Lim, E. (2016). Inertia based microfluidic capture and characterisation of circulating tumour cells for the diagnosis of lung cancer. Annals of Translational Medicine, 4 (24), 2016 doi: 10.21037/atm.2016.12.28

DOI BRAD record
NEW Khonsari, H., Schneider, M., Al-Mahdawi, S., Chianea, Y., Themis, M., Parris, C., Pook, M. and Themis, M. (2016). Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblasts. Khonsari, H., Schneider, M., Al-Mahdawi, S. et al. Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblasts. Gene Ther 23, 846–856 (2016). doi: 10.1038/gt.2016.61

DOI BRAD record
NEW Papa, S. and Bubici, C. (2016). Linking apoptosis to cancer metabolism: Another missing piece of JuNK. Salvatore Papa & Concetta Bubici (2016) Linking apoptosis to cancer metabolism: Another missing piece of JuNK, Molecular & Cellular Oncology, 3:2, doi: 10.1080/23723556.2015.1103398

DOI BRAD record
NEW Morris, R., Cooper, J., Shah, T., ..., Drenos, F. et al. (2016). Marginal role for 53 common genetic variants in cardiovascular disease prediction. Heart, 2016, 102 (20), pp. 1640 - 1647 doi: 10.1136/heartjnl-2016-309298

DOI BRAD record
NEW Slijepcevic, P. (2016). Mechanisms of the evolutionary chromosome plasticity: Integrating the ‘Centromere-from-Telomere' hypothesis with telomere length regulation. Cytogenetic and Genome Research, 148(4): pp. 268-278, (2016) doi: 10.1159/000447415

DOI BRAD record
NEW Liu, C., Kraja, A., Smith, J., ..., Drenos, F. et al. (2016). Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nature Genetics, 2016, 48 (10), pp. 1162 - 1170 doi: 10.1038/ng.3660

DOI BRAD record
NEW Drenos, F., Smith, G., Ala-Korpela, M. et al. (2016). Metabolic characterization of a rare genetic variation within APOC3 and its lipoprotein lipase-independent effects. Drenos F, Davey Smith G, Ala-Korpela M, Kettunen J, Würtz P, Soininen P, Kangas AJ, Dale C, Lawlor DA, Gaunt TR, Casas JP. Metabolic characterization of a rare genetic variation within APOC3 and its lipoprotein lipase–independent effects. Circulation: Cardiovascular Genetics. 2016 Jun;9(3):231-9. doi: 10.1161/CIRCGENETICS.115.001302

DOI BRAD record
NEW Wang, Q., Niironen, M., Tynkkynen, T., ..., Drenos, F. et al. (2016). Metabolic signatures of birthweight in 18 288 adolescents and adults. International Journal of Epidemiology, 45 (5), pp. 1539 - 1550, doi: 10.1093/ije/dyw255.

DOI BRAD record
NEW Martin, C., Murray, J., Carroll, P., ..., Vagnarelli, P. et al. (2016). Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis. Genes & Development, 30(19), pp. 2158-72. doi: 10.1101/gad.286351.116.

DOI BRAD record
NEW Pondman, K., Paudyal, B., Sim, R., ..., Stenbeck, G. et al. (2016). Pulmonary surfactant protein SP-D opsonises carbon nanotubes and augments their phagocytosis and subsequent pro-inflammatory immune response. Pondman KM, Paudyal B, Sim RB, Kaur A, Kouser L, Tsolaki AG, Jones LA, Salvador-Morales C, Khan HA, ten Haken B, Stenbeck G. Pulmonary surfactant protein SP-D opsonises carbon nanotubes and augments their phagocytosis and subsequent pro-inflammatory immune response. Nanoscale. 2017;9(3):1097-109. doi: 10.1039/C6NR08807D

DOI BRAD record
NEW McLachlan, S., Giambartolomei, C., White, J., ..., Drenos, F. et al. (2016). Replication and characterization of association between ABO SNPs and red blood cell traits by meta-analysis in Europeans. PLoS ONE, 2016, 11 (6), pp. 1 - 18 doi: 10.1371/journal.pone.0156914

DOI BRAD record
NEW Dimude, J., Midgley-Smith, S., Stein, M. and Rudolph, C. (2016). Replication termination: Containing fork fusion-mediated pathologies in escherichia coli. Genes, 7(8):40, pp. 1-22, (2016) doi: 10.3390/genes7080040

DOI BRAD record
NEW de Castro, I., Gokhan, E. and Vagnarelli, P. (2016). Resetting a functional G1 nucleus after mitosis. Chromosoma 125, pp. 607 - 619. doi: 10.1007/s00412-015-0561-6.

DOI BRAD record
NEW Khachatryan, V., Sirunyan, A., Tumasyan, A., ..., Tosi, S. et al. (2016). Search for Narrow Resonances in Dijet Final States at root s=8 TeV with the Novel CMS Technique of Data Scouting.

BRAD record
NEW Tulasidas, S., Mackay, R., Hudson, C. and Balachandran, W. (2016). Security Framework for Managing Data Security within Point of Care Tests. Journal of Software Engineering and Applications

BRAD record
NEW Lewis, A., Cave, P., Stern, M. et al. (2016). Singing for Lung Health—a systematic review of the literature and consensus statement. Lewis, A., Cave, P., Stern, M. et al. Singing for Lung Health—a systematic review of the literature and consensus statement. npj Prim Care Resp Med 26, 16080 (2016). doi: 10.1038/npjpcrm.2016.80

DOI BRAD record
NEW Hoefken, T., Kennedy, H., Haack, T., ..., Mackay, R. et al. (2016). Sudden cardiac death due to deficiency of the mitochondrial inorganic pyrophosphatase PPA2. Kennedy H, Haack TB, Hartill V, Mataković L, Baumgartner ER, Potter H, Mackay R, Alston CL, O’Sullivan S, McFarland R, Connolly G. Sudden cardiac death due to deficiency of the mitochondrial inorganic pyrophosphatase PPA2. The American Journal of Human Genetics. 2016 Sep 1;99(3):674-82. doi: 10.1016/j.ajhg.2016.06.027

DOI BRAD record
NEW Motevalli, A., Yasaei, H., Virmouni, S., Mirabdulhagh, M., Slijepcevic, P. and Roberts, T. (2016). Telomere elongation in the breast cancer cell line 21NT after treatment with an epigenetic modifying drug. Journal of Cancer Therapy, 07 (10): pp. 700 - 711,(2016) doi: 10.4236/jct.2016.710072

DOI BRAD record
NEW Ganesan, K., Gokhan, E., De Munter, S., Bollen, M., Vagnarelli, P., Peti, W. and Page, R. (2016). The Ki-67 and Repoman mitotic phosphatases assemble via an identical, yet novel mechanism. Kumar GS, Gokhan E, De Munter S, Bollen M, Vagnarelli P, Peti W, Page R. The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism. Elife. 2016 Aug 30;5:e16539. doi: 10.7554/eLife.16539.001

DOI BRAD record
NEW Ehret, G., Ferreira, T., Chasman, D., ..., Drenos, F. et al. (2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Ehret, G., Ferreira, T., Chasman, D. et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet 48, 1171–1184 (2016). doi: 10.1038/ng.3667

DOI BRAD record
NEW Mankarious, A., Dave, F., Pados, G., Tsolakidis, D., Gidron, Y., Pang, Y., Thomas, P., Hall, M. and Karteris, E. (2016). The pro-social neurohormone oxytocin reverses the actions of the stress hormone cortisol in human ovarian carcinoma cells in vitro. International Journal of Oncology, 48: pp.1805-1814. doi: 10.3892/ijo.2016.3410.

DOI BRAD record
NEW Seifert, W., Posor, Y., Schu, P., Stenbeck, G., Mundlos, S., Klaassen, S., Nürnberg, P., Haucke, V., Kornak, U. and Kühnisch, J. (2016). The progressive ankyloses protein ANK facilitates clathrin- and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface. Seifert W, Posor Y, Schu P, Stenbeck G, Mundlos S, Klaassen S, Nürnberg P, Haucke V, Kornak U, Kühnisch J. The progressive ankylosis protein ANK facilitates clathrin-and adaptor-mediated membrane traffic at the trans-Golgi network-to-endosome interface. Human molecular genetics. 2016 Sep 1;25(17):3836-48. doi: 10.1093/hmg/ddw230

DOI BRAD record
NEW Surendran, P., Drenos, F., Young, R. et al. (2016). Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Surendran, P., Drenos, F., Young, R. et al. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet 48, 1151–1161 (2016). doi: 10.1038/ng.3654

DOI BRAD record
NEW Beaney, K., Cooper, J., McLachlan, S., ..., Drenos, F. et al. (2016). Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids. Cardiovascular diabetology, 2016, 15 (1), pp. 115 - 115 doi: 10.1186/s12933-016-0435-0

DOI BRAD record
NEW Daykin, N., Mansfield, L., Payne, A. et al. (2016). What works for wellbeing in culture and sport? Report of a DELPHI process to support coproduction and establish principles and parameters of an evidence review. Perspectives in Public Health, (2016) doi: 10.1177/1757913916674038

DOI BRAD record

2015

NEW Davies, J., Chen, J., Pink, R., ..., Payne, A., Karteris, E. et al. (2015). (Under review) Orexin receptors exert a neuroprotective effect in Alzheimer's disease (AD) via heterodimerization with GPR103. Scientific Reports: Nature, 2015, Under review

BRAD record
NEW Sanghera, S., Frew, E. and Roberts, T. (2015). Adapting the CHEERS statement for reporting cost-benefit analysis. Pharmacoeconomics, 33(5): 533-534, (May 2015) doi: 10.1007/s40273-015-0265-z

DOI BRAD record
NEW Iansante, V., Choy, P., Chokshi, S., Williams, R., Anders, R., Bubici, C. and Papa, S. (2015). Addressing the interplay between apoptosis and glucose metabolism in liver cirrhosis and hcc. GUT, 64: pp. A12 - A12 (1),(2015) doi: 10.1136/gutjnl-2015-309861.22

DOI BRAD record
NEW Nüesch, E., Dale, C., Palmer, T., ..., Drenos, F. et al. (2015). Adult height, coronary heart disease and stroke: A multi-locus Mendelian randomization meta-analysis. International Journal of Epidemiology, 2016, 45 (6), pp. 1927 - 1937 doi: 10.1093/ije/dyv074

DOI BRAD record
NEW Rogers-Broadway, K. and Karteris, E. (2015). Amplification efficiency and thermal stability of qPCR instrumentation: Current landscape and future perspectives. Experimental and Therapeutic Medicine, 10: pp. 1261-1264, (2015) doi: 10.3892/etm.2015.2712

DOI BRAD record
NEW Beaney, K., Cooper, J., Shahid, S., Ahmed, W., Qamar, R., Drenos, F., Crockard, M. and Humphries, S. (2015). Clinical utility of a coronary heart disease risk prediction gene score in UK healthy middle aged men and in the Pakistani population. Beaney, K.E., Cooper, J.A., Shahid, S.U., Ahmed, W., Qamar, R., Drenos, F., Crockard, M.A. and Humphries, S.E. (2015) PLoS ONE, 10 (7), e0130754, pp. 1-13. doi: 10.1371/journal.pone.0130754.

DOI BRAD record
NEW Gérard, C., Mestdagt, M., Tskitishvili, E., ..., Silva, E. et al. (2015). Combined estrogenic and anti-estrogenic properties of estetrol on breast cancer may provide a safe therapeutic window for the treatment of menopausal symptoms. Oncotarget, 2015, 6 (19), pp. 17621 - 17636

BRAD record
NEW Beaney, K., Cooper, J., Shahid, S., Ahmed, W., Qamar, R., Drenos, F., Crockard, M. and Humphries, S. (2015). Correction: Clinical utility of a coronary heart disease risk prediction gene score in UK healthy middle aged men and in the Pakistani population PLoS ONE 10 (7). doi: 10.1371/journal.pone.0130754. PLoS ONE, 10 (9), pp. 1-1. doi: 10.1371/journal.pone.0139651.

DOI BRAD record
NEW Rinaldi, G., Yan, H., Nacif-Pimenta, R., Matchimakul, P., Bridger, J., Mann, V., Smout, M., Brindley, P. and Knight, M. (2015). Cytometric analysis, genetic manipulation and antibiotic selection of the snail embryonic cell line Bge from Biomphalaria glabrata, the intermediate host of Schistosoma mansoni. International Journal of Parasitology Research, 2015, 45 (8), pp. 527 - 535

BRAD record
NEW Owoka, T., Vetter, M., Federico, C., Saccone, S. and Tosi, S. (2015). Detection of t(7;12)(q36;p13) in paediatric leukaemia using dual colour fluorescence in situ hybridisation. Hematology and Leukemia, 3:4, (2015) doi: 10.7243/2052-434X-3-4

DOI BRAD record
NEW Kugathas, S., Audouze, K., Ermler, S., Orton, F., Rosivatz, E., Scholze, M. and Kortenkamp, A. (2015). Effects of common pesticides on prostaglandin D2 (PGD2) inhibition in SC5 mouse sertoli cells, evidence of binding at the cox-2 active site, and implications for endocrine disruption. Environmental Health Perspectives,124, (4): pp. 452 - 459, (2015) doi: 10.1289/ehp.1409544

DOI BRAD record
NEW Bikkul, M., Slijepcevic, P., Anderson, R., Faragher, R., Kill, I. and Bridger, J. (2015). Genome Organisation is affected in immortalised control and Hutchinson-Gilford Progeria Cells. 20th International Chromosome Conference (ICC), Canterbury, Kent University, England, 23, (2): pp. 392 - 393, 1-4 Septemebr 2015

BRAD record
NEW Anjomani-Virmouni, S., Al-Mahdawi, S., Sandi, C., Yasaei, H., Slijepcevic, P. and Pook, M. (2015). Identification of telomere dysfunction in Friedreich ataxia. EMBO Conference on Telomeres, Telomerase and Disease, Brussels, Belgium, 1-4 May, pp. 1-1.

BRAD record
NEW Anjomani-Virmouni, S., Al-Mahdawi, S., Sandi, C., Yasaei, H., Giunti, P., Slijepcevic, P. and Pook, M. (2015). Identification of telomere dysfunction in Friedreich ataxia. Molecular Neurodegeneration, 10, 22, pp. 1-11. doi: 10.1186/s13024-015-0019-6.

DOI BRAD record
NEW Iansante, V., Choy, P., Chokshi, S., Williams, R., Anders, R., Bubici, C. and Papa, S. (2015). Increased aerobic glycolysis is associated with poor outcome and suppression of apoptosis in human liver cirrhosis and hcc. Journal Of Hepatology,62: pp. S427 - S427 (1),(2015)

BRAD record
NEW Choy, P., Sufi, J., Glaser, S., Alpini, G., Heaton, N., Williams, R., Quaglia, A., Syn, W., Bubici, C. and Papa, S. (2015). Inhibition of mapk signalling promotes cell cycle arrest and sensitises intrahepatic cholangiocarcinoma cells to chemotherapy. GUT, 64: pp. A458 - A458 (1),(2015) doi: 10.1136/gutjnl-2015-309861.1003

DOI BRAD record
NEW Pondman, K., Pednekar, L., Paudyal, B., ..., Stenbeck, G. et al. (2015). Innate immune humoral factors, C1q and factor H, with differential pattern recognition properties, alter macrophage response to carbon nanotubes.

BRAD record
NEW Burugapalli, K., Wijesuriya, S., Mackay, R. and Balachandran, W. (2015). Insoluble electrospun membranes for analyte pre-concentration in saliva. Proc. ESA Annual Meeting on Electrostatics 2015

BRAD record
NEW Yan, K., Sisu, C., Cheng, C., Rozowsky, J., Meyerson, W. and Gerstein, M. (2015). Loregic: A Method to Characterize the Cooperative Logic of Regulatory Factors. PLOS COMPUTATIONAL BIOLOGY, 2015, 11 (4), pp. ? - ? (21) doi: 10.1371/journal.pcbi.1004132

DOI BRAD record
NEW Drenos, F., Grossi, E., Buscema, M. and Humphries, S. (2015). Networks in coronary heart disease genetics as a step towards systems epidemiology. PLoS ONE, 2015, 10 (5) doi: 10.1371/journal.pone.0125876

DOI BRAD record
NEW Davies, J., Chen, J., Pink, R., ..., Payne, A., Karteris, E. et al. (2015). Orexin receptors exert a neuroprotective effect in Alzheimer's disease (AD) via heterodimerization with GPR103. Scientific Reports, 5: 12584, (2015) doi: 10.1038/srep12584

DOI BRAD record
NEW Iansante, V., Choy, P., Fung, S., ..., Bubici, C. et al. (2015). PARP14 promotes the warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation. Nature Communications, ARTN 7882, 6, (2015) doi: 10.1038/ncomms8882

DOI BRAD record
NEW Tosi, S., Mostafa Kamel, Y., Owoka, T., Federico, C., Truong, T. and Saccone, S. (2015). Paediatric acute myeloid leukaemia with the t(7;12)(q36;p13) rearrangement: a review of the biological and clinical management aspects. Biomarker Research, 3(1),21, (2015) doi: 10.1186/s40364-015-0041-4

DOI BRAD record
NEW Oldoni, F., Palmen, J., Giambartolomei, C., Howard, P., Drenos, F., Plagnol, V., Humphries, S., Talmud, P. and Smith, A. (2015). Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3. Oldoni, F., Palmen, J., Giambartolomei, C., Howard, P., Drenos, F., Plagnol, V., Humphries, S.E., Talmud, P.J. and Smith, A.J.P. (2016) 'Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3', Atherosclerosis, 246, pp. 193-201. doi: 10.1016/j.atherosclerosis.2015.12.009.

DOI BRAD record
NEW Castro, I., Budzak, J., Di Giacinto, M. and Vagnarelli, P. (2015). Repo-Man as a chromatin organiser in the interphase nuclei. Gordon Reseach conference on Genome Architecture in Cell Fate & Disease, Hong Kong, 7-12 Jun 2015

BRAD record
NEW Sotiriadis, G., Dodagatta-Marri, E., Kouser, L., Alhamlan, F., Kishore, U. and Karteris, E. (2015). Surfactant proteins SP-A and SP-D modulate uterine contractile events in ULTR myometrial cell line. PLoS ONE, 10(12): pp 1-18, (2015) doi: 10.1371/journal.pone.0143379

DOI BRAD record
NEW Amelina, H., Subramaniam, S., Moiseeva, V., Armstrong, C., Pearson, S. and Tomita, K. (2015). Telomere protein Rap1 is a charge resistant scaffolding protein in chromosomal bouquet formation. BMC Biology, 2015, 13 (1), 37 (9 pp.) doi: 10.1186/s12915-015-0149-x

DOI BRAD record
NEW Fennell, A., Fernández-Álvarez, A., Tomita, K. and Cooper, J. (2015). Telomeres and centromeres have interchangeable roles in promoting meiotic spindle formation. Journal of Cell Biology, 2015, 208 (4), pp. 415 - 428 doi: 10.1083/jcb.201409058

DOI BRAD record
NEW Makarov, E. and Makarova, O. (2015). The 35S U5 snRNP is generated from the activated spliceosome during In vitro splicing. PLoS One, 10(5): e0128430, (2015) doi: 10.1371/journal.pone.0128430

DOI BRAD record
NEW Abbasi, M., Vassilopoulou, P., Stergioulas, L., Matich, M., Payne, A. and Smith, C. (2015). Use of creative tools, technologies, processes and practices in the sectors of Art, Media, and Architecture: State-of the-Art and desired future scenarios. Proceedings of the Digital Research in the Humanities and Arts conference, DRHA2014, London

BRAD record
NEW Gravells, P., Ahrabi, S., Vangala, R., ..., Tomita, K. et al. (2015). Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.

BRAD record