Research Clusters

Our research is organized across three scientific scales—from genes and cellular resilience to human health and the environment. These thematic areas bring together interdisciplinary experts to address the most complex biological and medical challenges of our time.

Genes and Cellular Resilience

Genome Organisation and Dynamics

Genome Organisation and Dynamics

Dr Ines Castro

We explore how the genome is organized to support healthy cell function, how this structure is passed through generations, and how it's affected by external stimuli, disease, and aging.

Our Experts

  • Joanna Bridger
  • Ines Castro
  • Paola Vagnarelli
  • Evgeny Makarov
  • Predrag Slijepcevic
  • Joseph Hetmanski

Genes and Human Health

Cancer Mechanisms

Cancer Mechanisms

Dr Ahmet Ucar

Our research investigates the genetic, epigenetic, and signaling pathways that drive cancer. We aim to understand disease progression, identify early diagnostic markers, and develop new, more effective treatments.

Our Experts

  • Annabelle Lewis
  • Concetta Bubici
  • Alessandro Esposito
  • Barbara Tanos
  • Terry Roberts
Disease and Therapeutics

Disease and Therapeutics

Dr Victor Hernandez

We focus on preventing and treating hereditary and acquired diseases. Our work includes gene therapy, molecular approaches, and the development of functional genomic tools with a strong emphasis on translational impact.

Our Experts

  • Victor Hernandez
  • Michael Themis
  • Sara Anjomani Virmouni
  • Christian Rudolph
  • Ruth Mackay
Genomic Informatics and Epidemiology

Genomic Informatics and Epidemiology

Dr Cristina Sisu

We are an interdisciplinary group using computational and statistical methods to analyze genomic data. Our goal is to understand the role of the genome in health and disease, and to develop new tools for diagnosis, prediction, and intervention.

Our Experts

  • Cristina Sisu
  • Fotios Drenos
  • Michelle Sahai

Tissue Resilience and the Environment

Tissue Homeostasis and Resilience

Tissue Homeostasis and Resilience

Dr Sibylle Ermler

Investigating how cells and tissues respond to and repair damage from environmental stressors. We focus on mechanisms protecting against tissue degeneration, premature aging, and disease.

Our Experts

  • Sibylle Ermler
  • Gudrun Stenbeck
  • Joseph Hetmanski
  • Barbara Tanos
  • Bin Zhang
  • David Tree
  • Ahmet Ucar
Space Biology

Space Biology

Prof Emmanouil Karteris

Studying how the human body adapts to extreme conditions. We perform experiments mimicking space-flight to understand molecular changes shaped by altered physical forces and gravity.

Our Experts

  • Emmanouil Karteris
  • Joanna Bridger
  • Alessandro Esposito
  • Paola Vagnarelli
Organ-on-a-Chip Group

Organ-on-a-Chip Group

Dr Ruth Mackay

This multidisciplinary team develops advanced in-vitro models that mimic human physiology, reducing reliance on animal testing and improving drug development accuracy, with a focus on women's health.
Visit OOC Group Page
CHRC

CHRC

Prof Rhona Anderson

The Centre for Health Effects of Radiological and Chemical Agents studies the health impacts of external environment agents, identifying genetic markers and promoting well-being through engagement.
Visit CHRC Group Page