Genes and Cellular Resilience
Genome Organisation and Dynamics
We explore how the genome is organized to support healthy cell
function,
how this structure is passed through generations, and how it's affected by external stimuli,
disease, and aging.
Our Experts
- Joanna Bridger
- Ines Castro
- Paola Vagnarelli
- Evgeny Makarov
- Predrag Slijepcevic
- Joseph Hetmanski
Genes and Human Health
Cancer Mechanisms
Our research investigates the genetic, epigenetic, and signaling
pathways
that drive cancer. We aim to understand disease progression, identify early diagnostic
markers,
and develop new, more effective treatments.
Our Experts
- Annabelle Lewis
- Concetta Bubici
- Alessandro Esposito
- Barbara Tanos
- Terry Roberts
Disease and Therapeutics
We focus on preventing and treating hereditary and acquired diseases.
Our
work includes gene therapy, molecular approaches, and the development of functional genomic
tools with a strong emphasis on translational impact.
Our Experts
- Victor Hernandez
- Michael Themis
- Sara Anjomani Virmouni
- Christian Rudolph
- Ruth Mackay
Genomic Informatics and Epidemiology
We are an interdisciplinary group using computational and statistical
methods to analyze genomic data. Our goal is to understand the role of the genome in health
and disease, and to develop new tools for diagnosis, prediction, and intervention.
Our Experts
- Cristina Sisu
- Fotios Drenos
- Michelle Sahai
Tissue Resilience and the Environment
Tissue Homeostasis and Resilience
Investigating how cells and tissues respond to and repair damage from
environmental stressors. We focus on mechanisms protecting against tissue degeneration,
premature aging, and disease.
Our Experts
- Sibylle Ermler
- Gudrun Stenbeck
- Joseph Hetmanski
- Barbara Tanos
- Bin Zhang
- David Tree
- Ahmet Ucar
Space Biology
Studying how the human body adapts to extreme conditions. We perform
experiments mimicking space-flight to understand molecular changes shaped by altered
physical
forces and gravity.
Our Experts
- Emmanouil Karteris
- Joanna Bridger
- Alessandro Esposito
- Paola Vagnarelli
Organ-on-a-Chip Group
This multidisciplinary team develops advanced in-vitro models that
mimic
human physiology, reducing reliance on animal testing and improving drug development
accuracy,
with a focus on women's health.
Visit OOC Group Page
CHRC
The Centre for Health Effects of Radiological and Chemical Agents
studies
the health impacts of external environment agents, identifying genetic markers and
promoting
well-being through engagement.
Visit CHRC Group Page